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Falcons vs 49ers Prediction 10/19/2025 Today’s NFL Picks
Pick details
Atlanta (3-2) vs San Francisco (4-2)
October 19, 2025 at 08:20 PM EDT
The Line: Betting Odds: San Francisco -2.5 — Over/Under: +47
In this article we will formulate a Falcons vs 49ers prediction for this NFL game on Sunday, October 19th at Levi’s Stadium in Santa Clara, California. Let’s take a look at the prediction for this week 7 matchup.
Atlanta also has wins against the Commanders and Vikings, while losing to the Panthers and Buccaneers. The Falcons have won three of their last four games and they are currently second in the NFC South standings. Atlanta has scored 20.0 points per game with 227.6 passing yards and 151.2 rushing yards per game, while they have allowed 20.0 points against per game this season. Michael Penix Jr has thrown for 1,168 yards, four touchdowns, and three interceptions, while Bijan Robinson has rushed for 484 yards and two scores on 83 carries this year.
San Francisco also has a loss against the Jaguars, but they have wins against the Rams, Cardinals, Saints, and Seahawks. The 49ers have lost two of their last three games and they are currently tied for first in the NFC West standings. San Francisco has scored 20.8 points per game with 291.5 passing yards and 82.2 rushing yards per game, while they have allowed 21.3 points against per game this season. Brock Purdy is questionable for this game, so we may see Mac Jones under center once again. Christian McCaffrey has led the team with 336 rushing yards, 444 receiving yards, and four total touchdowns.
The Falcons have lost each of their last eight games as road underdogs following a home win.
The Falcons have failed to cover the spread in seven of their last eight Sunday games as underdogs.
The 49ers have covered the spread in five of their last six games as favorites following a loss.
The Falcons have lost the first quarter in four of their last five Week 7 games.
The Falcons have lost the first half in four of their last five Week 7 games as underdogs.
The road team has won nine of the 49ers’ last 10 Week 7 games.
The 49ers have failed to cover the spread in each of their last nine home games against teams that held a winning record.
The underdogs have covered the spread in each of the 49ers’ last six Week 7 games.
The 49ers have lost the first quarter in three of their last four Week 7 home games against NFC opponents.
The Falcons have won the first half in each of their last four games against teams that held a winning record.
Each of the Falcons’ last four October games against NFC West opponents have gone UNDER the total points line.
Demarcus Robinson has scored a touchdown in four of his last five appearances with his team as a home favorite against NFC South opponents.
Brian Robinson has recorded 18+ rushing yards in 14 of his last 15 home appearances.
Brian Robinson has recorded 24+ rushing and receiving yards in each of his nine previous appearances with his team as a favorite following a loss.
Heading into Week 7, Eddy Pineiro has recorded the most made field goals without a failed attempt this season (15).
Bijan Robinson has recorded 90+ rushing yards in each of the Falcons’ last four games as road underdogs against NFC opponents.
Bijan Robinson has recorded 111+ rushing and receiving yards in each of the Falcons’ last five games against NFC opponents.
Kirk Cousins has recorded 274+ passing yards in four of his last five October appearances with his team as an underdog against NFC opponents.
Bijan Robinson has recorded 39+ receiving yards in four of the Falcons’ last five games.
Kirk Cousins has recorded 24+ completions in each of his last seven October appearances against NFC West opponents.
Heading into Week 7, Bijan Robinson has recorded the longest rush of the season (81 yards vs Bills, Week 6).
49ers – four different players have recorded 80+ receiving yards in a game this season – equal-most in the NFL, heading into Week 7.
Heading into Week 7, the Falcons rank 1st in the NFL in passing yards allowed per game (139.4) this season.
Heading into Week 7, the Falcons rank 1st in the NFL in 1st downs against (75) this season.
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Atlanta Falcons Betting Preview
The Atlanta Falcons are 3-2 this year after they defeated Buffalo by a score of 24-14 last week. Atlanta led 21-7 at halftime and added a field goal with 1:43 left to seal the victory. The Falcons out gained Buffalo by a total of 443-291, went 5-12 on third downs, and won the turnover battle by a total of 2-0 in the game. Michael Penix Jr went 20-32 for 250 yards and one touchdown, while Bijan Robinson rushed for 170 yards and one score on 19 carries. Drake London led the receivers with 10 receptions for 158 yards and one touchdown in the win. The Atlanta defense recorded four sacks and three tackles for loss in the game.Atlanta also has wins against the Commanders and Vikings, while losing to the Panthers and Buccaneers. The Falcons have won three of their last four games and they are currently second in the NFC South standings. Atlanta has scored 20.0 points per game with 227.6 passing yards and 151.2 rushing yards per game, while they have allowed 20.0 points against per game this season. Michael Penix Jr has thrown for 1,168 yards, four touchdowns, and three interceptions, while Bijan Robinson has rushed for 484 yards and two scores on 83 carries this year.
San Francisco 49ers Betting Preview
The San Francisco 49ers are 4-2 this season after they lost to Tampa Bay by a score of 30-19 last week. San Francisco trailed 20-16 at halftime and only managed three points in the second half for the loss. The 49ers out gained Tampa Bay by a total of 363-352, went 7-16 on third downs, and lost the turnover battle by a total of 2-0 in the game. Mac Jones went 27-39 for 347 yards and two interceptions, while Christian McCaffrey rushed 17 times for 54 yards and one score. Kendrick Bourne led the receivers with five catches for 142 yards in the loss. The SF defense recorded one sack and four tackles for loss in the game.San Francisco also has a loss against the Jaguars, but they have wins against the Rams, Cardinals, Saints, and Seahawks. The 49ers have lost two of their last three games and they are currently tied for first in the NFC West standings. San Francisco has scored 20.8 points per game with 291.5 passing yards and 82.2 rushing yards per game, while they have allowed 21.3 points against per game this season. Brock Purdy is questionable for this game, so we may see Mac Jones under center once again. Christian McCaffrey has led the team with 336 rushing yards, 444 receiving yards, and four total touchdowns.
Why the San Francisco 49ers will win
The 49ers have won each of their last nine games at Levi’s Stadium when playing with a rest advantage.The Falcons have lost each of their last eight games as road underdogs following a home win.
The Falcons have failed to cover the spread in seven of their last eight Sunday games as underdogs.
The 49ers have covered the spread in five of their last six games as favorites following a loss.
The Falcons have lost the first quarter in four of their last five Week 7 games.
The Falcons have lost the first half in four of their last five Week 7 games as underdogs.
Why the Atlanta Falcons will win
The 49ers have lost each of their last four Week 7 games as favorites.The road team has won nine of the 49ers’ last 10 Week 7 games.
The 49ers have failed to cover the spread in each of their last nine home games against teams that held a winning record.
The underdogs have covered the spread in each of the 49ers’ last six Week 7 games.
The 49ers have lost the first quarter in three of their last four Week 7 home games against NFC opponents.
The Falcons have won the first half in each of their last four games against teams that held a winning record.
Total Points Facts
Seven of the 49ers’ last eight games at Levi’s Stadium following a loss have gone OVER the total points line.Each of the Falcons’ last four October games against NFC West opponents have gone UNDER the total points line.
San Francisco 49ers Player Prop Facts
Demarcus Robinson has recorded 23+ receiving yards in each of his last five appearances against NFC opponents.Demarcus Robinson has scored a touchdown in four of his last five appearances with his team as a home favorite against NFC South opponents.
Brian Robinson has recorded 18+ rushing yards in 14 of his last 15 home appearances.
Brian Robinson has recorded 24+ rushing and receiving yards in each of his nine previous appearances with his team as a favorite following a loss.
Heading into Week 7, Eddy Pineiro has recorded the most made field goals without a failed attempt this season (15).
Atlanta Falcons Player Prop Facts
Bijan Robinson has scored at least one touchdown in each of the Falcons’ last four games following a home win.Bijan Robinson has recorded 90+ rushing yards in each of the Falcons’ last four games as road underdogs against NFC opponents.
Bijan Robinson has recorded 111+ rushing and receiving yards in each of the Falcons’ last five games against NFC opponents.
Kirk Cousins has recorded 274+ passing yards in four of his last five October appearances with his team as an underdog against NFC opponents.
Bijan Robinson has recorded 39+ receiving yards in four of the Falcons’ last five games.
Kirk Cousins has recorded 24+ completions in each of his last seven October appearances against NFC West opponents.
Heading into Week 7, Bijan Robinson has recorded the longest rush of the season (81 yards vs Bills, Week 6).
Matchup/League Facts
Heading into Week 7, the 49ers rank 1st in the NFL in passing yards per game (291.5) this season.49ers – four different players have recorded 80+ receiving yards in a game this season – equal-most in the NFL, heading into Week 7.
Heading into Week 7, the Falcons rank 1st in the NFL in passing yards allowed per game (139.4) this season.
Heading into Week 7, the Falcons rank 1st in the NFL in 1st downs against (75) this season.
Falcons vs 49ers Prediction
Atlanta is coming off of a dominating performance against Buffalo last week and they will look to keep that momentum here, but they will be on the road. The Falcons have scored 58 points in their last two games, but they did drop their last road game by a score of 30-0. San Francisco continues to deal with injuries and they lost last week against Tampa Bay. The 49ers have done a decent job offensively, but their defense has allowed 30, 23, and 26 in their last three games. Take the over in this matchup.David Racey is 37-21 (64%) in the NFL this season and he is currently #1 on the NFL Leaderboard. Click here for his premium plays for this week!
