Arizona Cardinals vs Cincinnati Bengals Prediction 12/28/2025 Today’s NFL Picks

The Arizona Cardinals and Cincinnati Bengals meet Sunday in NFL action at Paycor Stadium. Here’s a Arizona Cardinals vs Cincinnati Bengals Prediction. This article will include a Arizona Cardinals vs Cincinnati Bengals Pick.

Arizona Cardinals Betting Preview

The Arizona Cardinals lost to the Falcons and Texans, and play the Rams next. The Arizona Cardinals have lost 7 straight games. Jacoby Brissett is completing 65.2 percent of his passes for 2,911 yards, 19 touchdowns, and 7 interceptions. Trey McBride and Michael Wilson have combined for 1,916 receiving yards and 15 touchdowns, while Marvin Harrison Jr. has 41 receptions.

The Arizona Cardinals ground game is averaging 97.5 yards per contest, and Michael Carter leads the way with 286 yards and 1 touchdown. Defensively, Arizona is allowing 27.6 points and 350.5 yards per game. Budda Baker leads the Arizona Cardinals with 111 tackles, Josh Sweat has 11 sacks and Denzel Burke has 3 interceptions.

Cincinnati Bengals Betting Preview

The Cincinnati Bengals lost to the Ravens, beat the Dolphins, and they play the Browns next. The Cincinnati Bengals have lost 6 of their last 8 games. Joe Burrow is completing 63.5 percent of his passes for 1,268 yards, 12 touchdowns, and 4 interceptions. Ja’Marr Chase and Tee Higgins have combined for 1,976 receiving yards and 15 touchdowns, while Andrei Iosivas has 27 receptions.

The Cincinnati Bengals ground game is averaging 88.6 yards per contest, and Chase Brown leads the way with 846 yards and 4 touchdowns. Defensively, Cincinnati is allowing 30.5 points and 402.8 yards per game. Jordan Battle leads the Cincinnati Bengals with 119 tackles, Joseph Ossai has 5 sacks and Demetrius Knight Jr. has 2 interceptions.

Why the Cincinnati Bengals will win

• The Cardinals have lost each of their last 11 Sunday games as underdogs.
• The Bengals have won each of their last eight games as favorites without Drew Sample.
• The Cardinals have failed to cover the spread in six of their last seven games as underdogs without Sean Murphy-Bunting.
• The Bengals have covered the spread in six of their last seven games in December.
• The Bengals have won the first quarter in 10 of their last 13 games at Paycor Stadium following a road win.
• The Cardinals have lost the first half in each of their last five Sunday road games.

Why the Arizona Cardinals will win

• The Bengals have lost eight of their last nine games without Joe Burrow.
• The Cardinals have won four of their last six games as underdogs without Michael Carter.
• The Cardinals have covered the spread in 10 of their last 11 games as underdogs before a Division game.
• The Bengals have failed to cover the spread in six of their last seven home games against NFC opponents.
• The Bengals have lost the first quarter in each of their last four Week 17 games.
• The road team has won the first half in five of the last six games between the Cardinals and Bengals.

Total Points Facts

• Seven of the Bengals’ last eight games as home favorites have gone OVER the total points line.
• Each of the Cardinals’ last five road games without Michael Carter have gone UNDER the total points line.

Cincinnati Bengals Player Prop Facts

• Tee Higgins has scored the first touchdown in three of his last four December appearances.
• Chase Brown has scored two or more touchdowns in three of the Bengals’ last four games as favorites against teams that held a losing record.
• Tee Higgins has scored at least one touchdown in nine of his last 10 appearances at Paycor Stadium.
• Chase Brown has recorded 67+ rushing yards in five of the Bengals’ last six games as home favorites.
• Ja’Marr Chase has recorded 91+ receiving yards in each of his last eight appearances at Paycor Stadium.
• Chase Brown has recorded 90+ rushing and receiving yards in eight of the Bengals’ last nine games.
• Joe Burrow has recorded 281+ passing yards in seven of his eight previous home appearances in games with a total points line of at least 50.0.
• Joe Burrow has recorded 25+ completions in each of his eight previous home appearances in games with a total points line of at least 50.0.
• Heading into Week 17, Ryan Rehkow ranks 1st amongst qualified players for gross average yards per punt (51.3) this season.

Arizona Cardinals Player Prop Facts

• Trey McBride has scored at least one touchdown in each of the Cardinals’ last six road games.
• Jacoby Brissett has recorded 25+ completions in five of the Cardinals’ last six games as underdogs.
• Jacoby Brissett has recorded 258+ passing yards in eight of the Cardinals’ last 10 games as underdogs.
• Michael Carter has recorded 18+ receiving yards in seven of his last eight appearances with the Cardinals as underdogs following a loss.
• Jacoby Brissett has recorded 16+ rushing yards in three of the Cardinals’ last four Sunday road games.
• Heading into Week 17, Jacoby Brissett has recorded the most pass attempts in a single game this season (57 vs 49ers, Week 11).

Matchup/League Facts

• Heading into Week 17, the Bengals rank 32nd in the NFL in points allowed per game (30.5) this season.
• Heading into Week 17, the Bengals rank 32nd in the NFL in yards allowed per game (402.8) this season.
• Heading into Week 17, the Cardinals have suffered the equal-most losses when leading at HT this season (5).
• Heading into Week 17, the Cardinals are the only team to give up multiple 10+ point 1st quarter leads to lose this season.

Arizona Cardinals vs Cincinnati Bengals Prediction

The Cardinals are a bad team on both sides and are dealing with endless injuries as they’re just waiting for the season to end. However, that doesn’t mean we lay more than a touchdown with the Bengals. While talented on the offensive side, the Bengals’ defense is arguably the worst in the league. The Bengals are 31st in total defense and 32nd in scoring defense. This will be the first time in over a year since the Bengals are favorites of 6 or more points. I’m just not doing it. There are better games out there but if forced to pick I’m grabbing the points. I typically don’t lay huge numbers with teams that don’t play a lick of defense. The hook could be key as well.

Randy Chambers's Pick: Arizona Cardinals +7.5