Indianapolis Colts vs Jacksonville Jaguars Prediction NFL Picks 10/6/24

Pick details

Jacksonville Jaguars (0-4) vs Indianapolis Colts (2-2)

October 6, 2024 at 01:00 PM EDT

The Line: Betting Odds: Jacksonville Jaguars -2.5 / Indianapolis Colts +2.5 — Over/Under: 47.5

(Get latest betting odds)

The Indianapolis Colts and the Jacksonville Jaguars meet Sunday in NFL action from TIAA Bank Field. Here’s an Indianapolis Colts vs Jacksonville Jaguars prediction. We will look at this from a betting perspective and determine the best Colts vs Jaguars pick. We will examine:

The Indianapolis Colts’ recent form and player performance

The Jacksonville Jaguars’ recent form and player performance

Recent betting trends and streaks involving the Indianapolis Colts

Recent betting trends and streaks involving the Jacksonville Jaguars

Recent betting trends in games played between the Colts and Jaguars

A summary that ties it all together and produces a favorable betting outcome for the Colts vs Jaguars game

Indianapolis Colts Betting Preview

In their first action of the 2024 season, the Colts played the Houston Texans. Indianapolis took a tough loss 29-27 in that one, then followed it up with a 16-10 loss to the Packers in game two. The Cots would beat the Bears in Week 3 for their first win, though.

Indianapolis was able to keep it going with another victory over the Steelers last weekend. The Colts were up 17-3 by halftime but had to hang on for the win 27-24. Joe Flacco finished with 168 yards and two scores. Jonathan Taylor led the rush with 21 carries for 88 yards and a TD.

Jacksonville Jaguars Betting Preview

Over on the Jaguars’ side, they haven’t had any luck in the win column yet this year. Jacksonville started out with a 20-17 loss to the Dolphins, then an 18-13 loss to the Browns. The Jags took their biggest loss so far versus the Bills, falling 47-10 in game three.

Jacksonville played a much closer game last weekend versus the Texans but still lost. The Jaguars were outscored by a TD in the fourth quarter during a 24-20 defeat. Trevor Lawrence threw for 169 yards and two scores. Tank Bigsby added seven carries for 90 yards to pace the rush.

Total Points Facts

  • Seven of the Jaguars’ last eight games at EverBank Stadium following a road loss have gone UNDER the total points line.
  • Six of the Colts’ last seven Sunday games as underdogs have gone OVER the total points line.
  • Each of the last three Sunday games at EverBank Stadium have gone UNDER the total points line.

Jacksonville Jaguars Player Prop Facts

  • Trevor Lawrence has recorded 262+ passing yards in four of the Jaguars’ last five games as favorites against AFC South opponents.
  • Travis Etienne has recorded 27+ receiving yards in five of the Jaguars’ last six games as favorites against AFC South opponents.
  • Trevor Lawrence has recorded 21+ rushing yards in four of his last five appearances with the Jaguars as favorites following a road loss.
  • Travis Etienne has scored at least one touchdown in each of the Jaguars’ last four October games against AFC opponents.
  • Tank Bigsby has recorded 32+ rushing and receiving yards in three of the Jaguars’ last four games following a road loss.
  • Trevor Lawrence has thrown two touchdowns in four of the Jaguars’ last five games against AFC South opponents.
  • Ronald Darby is just two away from 10 career interceptions.

Indianapolis Colts Player Prop Facts

  • Jonathan Taylor has scored the first touchdown in four of his last five appearances with the Colts as underdogs on the East Coast.
  • Kylen Granson has recorded 23+ receiving yards in four of the Colts’ last five games following a home win.
  • Jonathan Taylor has recorded 88+ rushing yards in four of the Colts’ last five Sunday games.
  • Jonathan Taylor has scored at least one touchdown in nine of his last 10 appearances.
  • Jonathan Taylor is just one away from 50 career touchdowns (including playoffs).

Indianapolis Colts vs Jacksonville Jaguars Prediction

I’m going to stay with Indianapolis. The Colts gave up 404 total yards (282 passing) and 23 first downs to the Steelers in their latest win but took advantage of a couple of fumble recoveries on defense to help bolster a mostly competent offensive performance. Another outing like that on Sunday and the Colts will be in good shape.

As for Jacksonville, they weren’t great on either side versus Houston but were still in a position to win down the stretch. The Jags totaled 313 yards (155 passing) with a rough 4-of-12 on third-down tries offensively and benefited from 12 Texans penalties. If the Colts can hang on to the ball and post a good number of third-down conversions this will be an Indy road cover/win. 

Andrew Jett's Pick: Indianapolis Colts +2.5

Hot Cappers

Latest Picks & Game Previews

  • Arsenal FC Arsenal FC vs Liverpool Liverpool Prediction 8/31/2025 Today’s EPL Picks

    August 31, 2025

  • Cardinals vs Reds Prediction 8/31/2025 Today’s MLB Picks

    August 31, 2025

  • San Diego Padres vs Minnesota Twins Prediction 8/31/2025 Today’s MLB Picks

    August 31, 2025

  • Brewers vs Blue Jays Prediction 8/31/2025 Today’s MLB Picks

    August 31, 2025

  • Tampa Bay Rays vs Washington Nationals Prediction 8/31/2025 Today’s MLB Picks

    August 31, 2025

  • Mariners vs Guardians Prediction 8/31/2025 Today’s MLB Picks

    August 31, 2025

  • Crystal Palace vs Aston Villa Prediction 8/31/2025 Today’s EPL Picks

    August 31, 2025

  • Virginia Tech vs South Carolina Prediction 8/31/2025 Today’s College Football Picks

    August 31, 2025

  • Chicago Cubs vs Colorado Rockies Prediction 8/31/2025 Today’s MLB Picks

    August 31, 2025

  • Baltimore Orioles vs San Francisco Giants Prediction 8/31/2025 Today’s MLB Picks

    August 31, 2025