Nov 23, 2025; Phoenix, Arizona, USA; San Antonio Spurs guard Devin Vassell (24) grabs a pass in the second half of the game at Mortgage Match Up Center. Mandatory Credit: Arianna Grainey-Imagn Images
Arianna Grainey-Imagn Images

San Antonio Spurs vs Portland Trail Blazers Prediction 11/26/2025 Today’s NBA Picks

Pick details

MATCHUP San Antonio Spurs Portland Trailblazers
Team Records 11-5 8-10
Spread +1.5 -118 -1.5 -102
Moneyline -105 -115
Total Over 240.5 (-110) Under 240.5 (-110)
Where Moda Center, Portland, OR
When Wednesday, November 26, 2025
Time 10:00 PM EST
TV KUNP 16

The San Antonio Spurs and Portland Trail Blazers meet Wednesday in NBA action at the Moda Center. Here’s a San Antonio Spurs vs Portland Trail Blazers Prediction. This article will include a San Antonio Spurs vs Portland Trail Blazers Pick.

San Antonio Spurs Betting Preview

The San Antonio Spurs beat the Hawks, lost to the Suns, and they play the Nuggets next. The Spurs have won 10 of their last 16 games.

The San Antonio Spurs are averaging 119.3 points on 49.8 percent shooting and allowing 112.3 points on 45.1 percent shooting. Victor Wembanyama is averaging 26.2 points and 12.9 rebounds, while De’Aaron Fox is averaging 23.1 points and 6.6 assists. Stephon Castle is the third double-digit scorer and Dylan Harper is dishing 3.8 assists. The San Antonio Spurs are shooting 36.6 percent from beyond the arc and 78.8 percent from the free throw line. The San Antonio Spurs are allowing 39.4 percent shooting from deep and are grabbing 45.1 rebounds per game.

Portland Trail Blazers Betting Preview

The Portland Trail Blazers lost to the Thunder, beat the Bucks, and they play the Thunder next. The Trail Blazers have lost 8 of their last 12 games.

The Portland Trail Blazers are averaging 121.2 points on 45 percent shooting and allowing 122.5 points on 48.7 percent shooting. Deni Avdija is averaging 25.9 points and 6.7 rebounds, while Shaedon Sharpe is averaging 22.6 points and 5 rebounds. Jerami Grant is the third double-digit scorer and Jrue Holiday is grabbing 5.3 rebounds. The Portland Trail Blazers are shooting 32.6 percent from beyond the arc and 81.1 percent from the free-throw line. The Portland Trail Blazers are allowing 36.7 percent shooting from deep and are grabbing 45.4 rebounds per game.

Why the Portland Trail Blazers will win

  • The Spurs have lost seven of their eight previous night games at Moda Center following a road loss.
  • The favorites have won 13 of the last 14 games between the Spurs and Trail Blazers.
  • The home team has covered the spread in each of the last six games between the Spurs and Trail Blazers.
  • The Spurs have failed to cover the spread in seven of their last eight road games against teams that held a losing record.

Why the San Antonio Spurs will win

  • The underdogs have won five of the Trail Blazers’ last six games at Moda Center.
  • The Trail Blazers have lost five of their last six games as home favorites following a win.
  • The Trail Blazers have failed to cover the spread in each of their last six games as favorites against Western Conference opponents following a win.
  • The Spurs have covered the spread in each of their last six games as underdogs following a road loss.

Total Points Facts

  • Nine of the Trail Blazers’ last 10 games as favorites have gone OVER the total points line.
  • Each of the Spurs’ last four games against Western Conference opponents have gone UNDER the total points line.

Portland Trail Blazers Player Facts

  • Robert Williams III leads all Trail Blazers players for blocks per 36 minutes (3.0) this season.
  • Jerami Grant ranks 17th in the Western Conference amongst qualified players for 3P% (41.8%) this season.

San Antonio Spurs Player Facts

  • De’Aaron Fox is one of only 15 qualified Guards in the league shooting at least 50% from the field this season.
  • Devin Vassell ranks 13th amongst qualified Forwards for three-pointers made per game (2.5) this season.

Matchup/League Facts

  • The Trail Blazers rank 2nd in the league for offensive rebounds per game this season (15.6).
  • The Trail Blazers rank 29th in the league for opponent blocks per game this season (6.1).
  • The Spurs rank 3rd in the league for opponent offensive rebounds per game this season (10.3).
  • The Spurs rank 3rd in the league for opponent blocks per game this season (3.8).

San Antonio Spurs vs Portland Trail Blazers Injury Report

The Trail Blazers will be without Damian Lillard, Blake Wesley, Jrue Holiday, Matisse Thybulle, and Scoot Henderson. Shaedon Sharpe is questionable.

The Spurs will be without Jordan McLaughlin, Victor Wembanyama, and Stephon Castle. Dylan Harper is questionable with a calf issue.

San Antonio Spurs vs Portland Trail Blazers Prediction

The Trail Blazers are going to get the benefit of the doubt because they’re at home, but they’re in such a funk right now and so banged up, I have trouble backing them as a favorite. The Spurs have injuries of their own, but they’re still finding ways to win and can score the ball at an above average clip. The Spurs could also get a boost in this game with the potential return of Dylan Harper, who is questionable instead of out at the time of this writing. The Spurs have won 6 of the last 8 games against the Trail Blazers. I’ll grab the bucket.

Randy Chambers's Pick: San Antonio Spurs +1.5

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