Portland Trail Blazers vs Detroit Pistons Prediction 12/5/2025 Today’s NBA Picks

The Portland Trail Blazers invade Little Caesars Arena to take on the Detroit Pistons on Friday night. Here’s a Portland Trail Blazers vs Detroit Pistons Prediction. This article will include a Portland Trail Blazers vs Detroit Pistons Pick.

Portland Trail Blazers Betting Preview 

The Portland Trail Blazers have been in a slump as they’ve lost eight of their last 11 games, but they will be feeling much better after they snapped a three-game skid with a 122-110 road win over the Cavaliers on Wednesday. Deni Avdija led the team with 27 points, eight rebounds and seven assists, Caleb Love and Shaedon Sharpe each scored 20 points while Tounami Camara chipped in with 17 points, six rebounds and four assists.

As a team, the Trail Blazers shot 44 percent from the field and 14 of 34 from the 3-point line as they looked like a new team in the first half where they poured in 68 points to build an 18-point lead. This turned out to be more than enough to hold off a late rally from the Cavaliers who couldn’t get closer than eight points.

Detroit Pistons Betting Preview 

Meanwhile, the Detroit Pistons were red-hot to start the season, but they’ve cooled off with three losses from their past five outings. They will be hoping to bounce back after falling just short to the struggling Bucks in a 113-109 road defeat on Wednesday. Tobias Harris led the team in scoring with 20 points on seven of 14 shooting, Cade Cunningham added 17 points with seven rebounds and seven assists while Jaden Ivey chipped in with 15 points off the bench.

As a team, the Pistons shot just 40 percent from the field and 14 of 43 from the 3-point line as they got off to a solid start. They looked to be in control after pouring in 33 points in the third quarter to take a 10-point lead. However, they let themselves down in the fourth quarter where they allowed 35 points to lose the lead for good with 1:34 left on the clock. 

Why the Detroit Pistons will win

• The Pistons have won each of their last eight Friday night games against Northwest Division opponents that held a losing record.
• The Trail Blazers have lost eight of their last nine night games against Eastern Conference opponents that held a winning record.
• The Pistons have covered the spread in each of their last eight Friday night games against Northwest Division opponents that held a losing record.
• The Trail Blazers have failed to cover the spread in each of their last four road games following a win.

Why the Portland Trail Blazers will win

• The Pistons have lost each of their last four games as favorites following a loss.
• The Trail Blazers have won eight of their last 12 games as underdogs after winning as underdogs.
• The Trail Blazers have covered the spread in each of their last 12 games as road underdogs against Central Division opponents.
• The Pistons have failed to cover the spread in seven of their last eight games as home favorites against Northwest Division opponents.

Total Points Facts

• Each of the Trail Blazers’ last four night games against Central Division opponents have gone UNDER the total points line.
• Five of the Pistons’ last six night games on the first leg of a back-to-back have gone UNDER the total points line.

Detroit Pistons Player Facts

• Isaiah Stewart ranks 4th amongst qualified players for blocks per game (1.9) this season.
• Ausar Thompson ranks 15th amongst qualified players for steals per game (1.6) this season.

Portland Trail Blazers Player Facts

• Jerami Grant ranks 20th in the Western Conference amongst qualified players for points per game (19.0) this season.
• Toumani Camara ranks T14th amongst qualified Forwards for three-pointers made per game (2.5) this season.

Matchup/League Facts

• The Pistons rank 1st for points in the paint per game (57.5) this season.
• The Pistons rank 2nd in the league for rebounds per game this season (46.9).
• The Trail Blazers rank 29th in the league for opponent steals per game this season (10.5).
• The Trail Blazers rank 29th in the league for turnovers per game this season (16.5).

Portland Trail Blazers vs Detroit Pistons Prediction

The Trail Blazers are still missing a host of players including Damian Lillard, Scoot Henderson, Jrue Holiday and Robert Williams III, while the Pistons are keeping eyes on Marcus Sasser and Duncan Robinson who are both questionable. The Trail Blazers were good enough to take down a banged up Cavaliers team in their last game, but they were ice-cold before that win. I have more trust in the Pistons who were red-hot before dropping a few close ones.

The line is reasonable for this one, so while the Trail Blazers can pull off the upset if Avdija has a monster game. I think the more probable outcome is that the Pistons get a much needed win at home behind a big game from Cunningham.

Peter Tran's Pick: Detroit -6.5