Feb 22, 2026; Minneapolis, Minnesota, USA; Philadelphia 76ers guard Tyrese Maxey (0) and guard Vj Edgecombe (77) look on during the second half against the Minnesota Timberwolves at Target Center. Mandatory Credit: Matt Krohn-Imagn Images
Matt Krohn-Imagn Images

Philadelphia 76ers vs Indiana Pacers Prediction 2/24/2026 Today’s NBA Picks

Pick details

MATCHUP Philadelphia 76ers Indiana Pacers
Team Records 31-26 15-43
Spread -8.5 -120 +8.5 100
Moneyline -395 +310
Total Over 233.5 (-110) Under 233.5 (-110)
Where Gainbridge Fieldhouse, Indianapolis, IN
When Tuesday, February 24, 2026
Time 07:00 PM EST
TV FanDuel SN IN

The Philadelphia 76ers pay a visit to the Indiana Pacers at the Gainbridge Fieldhouse on Tuesday night. Here’s a Philadelphia 76ers vs. Indiana Pacers prediction. This article will include a Philadelphia 76ers vs. Indiana Pacers pick.

Philadelphia 76ers Betting Preview 

The Philadelphia 76ers have been doing it tough lately as they’ve lost five of their last seven games overall, but they will be feeling much better after they arrest a four-game slide with a 135-108 road win over the red-hot Timberwolves on Sunday. Tyrese Maxey led the team with 39 points and eight assists, VJ Edgecombe added 24 points, Quentin Grimes scored 19 points off the bench, and Kelly Oubre Jr. chipped in with 18 points.

As a team, the 76ers shot 52 percent from the field and 21 of 37 from the 3-point line as they stormed out of the gates with 68 points in the first half to take a 10-point lead into halftime before they ran away with it in the second half to secure one of their more dominant wins of the season against a quality opponent in the Timberwolves. 

Indiana Pacers Betting Preview 

Meanwhile, the Indiana Pacers have been in a real slump as they’ve lost seven of their last nine games overall, and they will be hoping to snap a three-game skid after getting beaten by the Mavericks in a 134-130 loss on Sunday. Pascal Siakam led the team with 30 points, eight rebounds, and three assists on 12 of 19 shooting; Andrew Nembhard added 22 points with 11 assists, while Jarace Walker chipped in with 18 points, nine rebounds, and six assists.

As a team, the Pacers shot 50 percent from the field and 20 of 42 from the 3-point line as they hit the ground running with 66 points in the first half, but even though they never trailed by more than 11 points, they were always a couple steps behind the Mavericks, who didn’t look like a team riding a 10-game losing streak at all. 

Why the Indiana Pacers will win

  • The underdogs have won each of the 76ers’ last three games.
  • The 76ers have lost three of their last four games as favorites against Eastern Conference opponents following a win.
  • The home team has covered the spread in each of the last four games between the 76ers and Pacers.
  • The 76ers have failed to cover the spread in six of their last seven night games at Gainbridge Fieldhouse.

Why the Philadelphia 76ers will win

  • The Pacers have lost 20 of their last 23 games against Eastern Conference opponents that held a winning record.
  • The 76ers have won six of their last seven night games against Pacers teams that held a losing record.
  • The 76ers have covered the spread in eight of their last 10 games as road favorites against Eastern Conference opponents.
  • The Pacers have failed to cover the spread in four of their last five games against Atlantic Division opponents that held a winning record.

Total Points Facts

  • Seven of the 76ers’ last eight road games against the Pacers following a road win have gone OVER the total points line.
  • Each of the last four games between the 76ers and Pacers have gone UNDER the total points line.

Matchup/League Facts

  • The Pacers have used 31 different starting fives this season – equal-most in the league.
  • The Pacers rank 30th in the league for points per possession this season (1.10).
  • The 76ers rank 30th in the league for Q3 win percentage this season (31.6%).
  • The 76ers rank 2nd in the league for Q2 points per game this season (30.3).

Philadelphia 76ers vs Indiana Pacers Prediction

The 76ers could be shorthanded again with Joel Embiid listed as questionable, while the Pacers have ruled out Tyrese Haliburton, Obi Toppin, and Aaron Nesmith, with TJ McConnell listed as questionable and Pascal Siakam listed as doubtful. These teams have already clashed twice this season, with the 76ers winning both meetings, and I think that trend continues here.

The 76ers could be missing some firepower if Embiid is ruled out, but they still have more than enough to get past this ice-cold Pacers squad missing almost all of their best players. The line is a bit hefty, but I think the 76ers take care of business in this spot.

Peter Tran's Pick: Philadelphia -9.5

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