Los Angeles Lakers vs Minnesota Timberwolves Prediction 10/29/2025 Today’s NBA Picks

The Los Angeles Lakers travel to the Target Center to take on the Minnesota Timberwolves on Wednesday night. Here’s a Los Angeles Lakers vs Minnesota Timberwolves Prediction. This article will include a Los Angeles Lakers vs Minnesota Timberwolves Pick.

Los Angeles Lakers Betting Preview 

The Los Angeles Lakers have been in decent shape as they’ve split their first four games, but they will be hoping to bounce back here after getting routed by the Trail Blazers in a 122-108 home loss on Monday. Without LeBron James or Luka Doncic in the lineup once again, Austin Reaves did his best as he finished with 41 points and five assists on 13 of 22 shooting, while Rui Hachimura, Deandre Ayton and Dalton Knecht each scored 16 points.

As a team, the Lakers shot 46 percent from the field and just seven of 27 from the 3-point line. They played well enough to stay within striking distance until late in the third quarter where the Trail Blazers started to pull away. 

Minnesota Timberwolves Betting Preview 

Meanwhile, the Minnesota Timberwolves have also split their first four games and they will be eager to make amends after getting beaten by the Nuggets in a 127-114 home defeat on Monday. Jaden McDaniels led the team with 25 points and four blocks on 10 of 16 shooting, Julius Randle added 24 points with seven rebounds, while Naz Reid chipped in with 18 points off the bench.

As a team, the Timberwolves shot 47 percent from the field and 10 of 32 from the 3-point line as they poured in 35 points in the second quarter to take the lead into halftime. Only to get blown out by 70-49 in the second half as they had no answer for the Nuggets’ duo of Nikola Jokic and Jamal Murray who combined for 68 points on 25 of 39 shooting.

Why the Minnesota Timberwolves will win

• The favorites have won each of the Lakers’ last nine games at Target Center.
• The Lakers have lost nine of their last 10 games at Target Center.
• The Timberwolves have covered the spread in each of their last five home games against Western Conference opponents following a loss.
• The Lakers have failed to cover the spread in each of their last four road games against Northwest Division opponents.

Why the Los Angeles Lakers will win

• The Lakers have won three of their last five games as underdogs following a loss.
• The Timberwolves have failed to cover the spread in each of their last four games against Western Conference opponents.
• The road team has covered the spread in four of the Lakers’ last five games.

Total Points Facts

• Seven of the Lakers’ last eight games as underdogs have gone OVER the total points line.
• Seven of the Timberwolves’ last eight home games against Western Conference opponents have gone OVER the total points line.

Los Angeles Lakers vs Minnesota Timberwolves Prediction

The Lakers are still missing a bunch of players including LeBron James, Luka Doncic, Maxi Kleber and Gabe Vincent, while the Timberwolves have ruled out Anthony Edwards with Jaylen Clark listed as questionable. Both teams are missing some key players, but it’s the Lakers who are certainly more depleted in this matchup.

I think the Timberwolves still have the edge in defense and depth to justify them being favorites at home, but I still think the line is too high. I have the Lakers staying close thanks to another big game from Reaves who has really stepped up lately.