Mar 23, 2026; Detroit, Michigan, USA; Detroit Pistons Kevin Huerter (27) defends against Los Angeles Lakers Austin Reaves (15) during the second half at Little Caesars Arena. Mandatory Credit: David Reginek-Imagn Images
David Reginek-Imagn Images

Los Angeles Lakers vs Indiana Pacers Prediction 3/25/2026 Today’s NBA Picks

Pick details

MATCHUP Los Angeles Lakers Indiana Pacers
Team Records 46-26 16-56
Spread -10.5 -105 +10.5 -115
Moneyline -535 +400
Total Over 239.5 (-105) Under 239.5 (-115)
Where Gainbridge Fieldhouse, Indianapolis, IN
When Wednesday, March 25, 2026
Time 07:00 PM EDT
TV Spectrum Sports Net

The Los Angeles Lakers and the Indiana Pacers collide at the Gainbridge Fieldhouse on Wednesday night. Here’s a Los Angeles Lakers vs. Indiana Pacers Prediction. This article will include a Los Angeles Lakers vs. Indiana Pacers Pick.

Los Angeles Lakers Betting Preview 

The Los Angeles Lakers have been on a tear, as they’ve won 12 of their last 14 games overall, but they will be hoping to bounce back in this one after having their nine-game win streak halted by the Pistons in a 113-110 road defeat on Monday. Luka Doncic led the team with 32 points, seven rebounds and six assists; Austin Reaves added 24 points with five assists, while LeBron James tallied 12 points with nine rebounds and 10 assists.

As a team, the Lakers shot 48 percent from the field and eight of 29 from the 3-point line as they had to work hard to claw their way back from an early 16-point deficit to take the lead early in the fourth quarter, only to allow the Pistons to go on a 10-3 run to slip away in the end. Jaxson Hayes was the only impactful player off the bench, as he had 11 points with two steals and four blocks, but Luke Kennard shot just one of five from the field for his six points.

Indiana Pacers Betting Preview 

Meanwhile, the Indiana Pacers have been in terrible form, as they have lost 20 of their last 23 games overall, but they must be feeling much better after they snapped a 16-game losing streak with a 128-126 road win over the Magic on Monday. Pascal Siakam led the team with 37 points on 13 of 26 shooting, Jarace Walker added 20 points, Aaron Nesmith scored 19 points, and Andrew Nembhard tallied 13 points with seven rebounds and 14 assists.

As a team, the Pacers shot 55 percent from the field and 16 of 35 from the 3-point line as they exploded for 44 points in the third quarter to open up an 11-point lead, which proved to be crucial as they saw their lead get cut to just two points with 29.6 seconds left on the clock before they escaped with the narrow win. 

Why the Indiana Pacers will win

  • The underdogs have won three of the Lakers’ last four games.
  • The Lakers have lost six of their last nine games as favorites against Central Division opponents.
  • The underdogs have covered the spread in six of the Lakers’ last seven games at Gainbridge Fieldhouse.
  • The Lakers have failed to cover the spread in each of their last three road games against Central Division opponents that held a losing record.

Why the Los Angeles Lakers will win

  • The Pacers have lost each of their last 11 night games against Western Conference opponents.
  • The Lakers have won each of their last nine night games against teams that held a losing record.
  • The Lakers have covered the spread in each of their last seven games following a road loss.
  • The Pacers have failed to cover the spread in each of their last four games against Pacific Division opponents.

Total Points Facts

  • Each of the Pacers’ last five games as underdogs has gone OVER the total points line.
  • Each of the Lakers’ last four games as favorites following a road loss have gone OVER the total points line.

Los Angeles Lakers vs Indiana Pacers Prediction

The Lakers are still keeping an eye on Adou Thiero, Marcus Smart and Rui Hachimura, who are all questionable, while the Pacers are still missing Tyrese Haliburton and Ivica Zubac, but they expect to have Aaron Nesmith, Obi Toppin and Pascal Siakam all available.

These two squads last met on Mar 6 and it was the Lakers who rolled to a 128-117 win at home. The Pacers deserve plenty of credit for their comeback win over the Magic in their last outing, but I think they come back down to Earth with a tough loss in this matchup. The Lakers have been on a roll for a while now and I think they will come out swinging after losing a tough one in their last outing.

Peter Tran's Pick: LA Lakers -10.5