Detroit Pistons vs Boston Celtics Prediction 11/26/2025 Today’s NBA Picks

The Detroit Pistons and the Boston Celtics duke it out at the TD Garden on Wednesday night. Here’s a Detroit Pistons vs Boston Celtics Prediction. This article will include a Detroit Pistons vs Boston Celtics Pick.

Detroit Pistons Betting Preview 

The Detroit Pistons have been on fire to start the season as they’ve won 15 of their first 17 games. They will be looking to build on their current 13-game win streak after sneaking past the struggling Pacers in a 122-117 road win on Monday. Cade Cunningham led the team with 24 points, 11 rebounds and six assists, Caris LeVert added 19 points off the bench while JAlen Duren chipped in with 17 points and 12 rebounds.

As a team, the Pistons shot 50 percent from the field and nine of 25 from the 3-point line as they dominated from the start and poured in 71 points in the first half to take a 19-point lead. This proved to be just enough in the end as the Pistons saw their lead cut to just two points with 15.4 seconds left before they escaped on free throws from Cunningham.

Boston Celtics Betting Preview 

Meanwhile, the Boston Celtics have been in fine form as they’ve won four of their last five games overall and they will be eager to keep it going after taking down the Magic in a 138-129 home win on Sunday. Jaylen Brown led the team with 35 points and eight assists on 14 of 26 shooting, Anfernee Simons added 23 points on eight of 11 shooting off the bench while Payton Pritchard chipped in with 19 points and eight assists on nine of 16 shooting.

As a team, the Celtics shot 60 percent from the field and 15 of 33 from the 3-point line as they caught fire early with 48 points in the second quarter to take a 26-point lead. They survived a late rally from the Magic who cut their lead to just six points at one stage. 

Why the Boston Celtics will win

• The Celtics have won each of their last seven games against the Pistons at TD Garden.
• The Pistons have lost 11 of their last 12 night games against Celtics teams that held a winning record.
• The Celtics have covered the spread in each of their last four games as home underdogs against Central Division opponents.
• The Pistons have failed to cover the spread in five of their last six games as road favorites following a road win.

Why the Detroit Pistons will win

• The Pistons have won each of their last 10 games against Eastern Conference opponents.
• The Celtics have lost three of their last four games against Eastern Conference opponents following a win.
• The Celtics have failed to cover the spread in seven of their last eight night games following a home win.
• The Pistons have covered the spread in each of their last five games at TD Garden when playing with a rest disadvantage.

Total Points Facts

• Each of the Pistons’ last seven Wednesday night games at TD Garden have gone OVER the total points line.
• Five of the Celtics’ last six home games against the Pistons following a home win have gone OVER the total points line.

Boston Celtics Player Facts

• Payton Pritchard is one of only 12 players in the league to have made 8+ threes in a game this season.
• Anfernee Simons ranks 12th amongst qualified players for three-pointers made per 36 minutes (3.9) this season.

Detroit Pistons Player Facts

• Isaiah Stewart ranks T2nd amongst qualified players for blocks per game (2.0) this season.
• Ausar Thompson rank 12th amongst qualified players for steals + blocks per game (2.5) this season.

Matchup/League Facts

• The Celtics rank 30th in the league for free throws made per game this season (14.4).
• The Celtics rank 30th in the league for free throw attempts per game this season (18.6).
• The Pistons rank 1st for points in the paint per game (59.1) this season.
• Nine different Pistons players have scored 20+ points in a game this season – equal-most in the league.

Detroit Pistons vs Boston Celtics Prediction

The Pistons are still missing Marcus Sasser and Bobi Klintman, while the Celtics have ruled out Neemias Queta and Jayson Tatum. These teams last met on Oct 26 and it was the Pistons who won by 119-113  despite falling into an early 17-point deficit. The Celtics will be out for revenge and they’ve been building momentum over the last five games, but it’s the Pistons who open as favorites given that they are one of the hottest teams in the league right now. The Pistons were unconvincing in their narrow win over the slumping Pacers on Monday, but I think they can take down the Celtics again and I like them at the short line in this spot.

Peter Tran's Pick: Detroit -2.5