Oct 22, 2025; New York, New York, USA; Cleveland Cavaliers guard Donovan Mitchell (45) reacts during the fourth quarter against the New York Knicks at Madison Square Garden. Mandatory Credit: Brad Penner-Imagn Images
Brad Penner-Imagn Images

Cleveland Cavaliers vs Brooklyn Nets Prediction 10/24/2025 Today’s NBA Picks

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Cleveland (0-1) vs Brooklyn (0-1)

October 24, 2025 at 07:30 PM EDT

The Line: Betting Odds: Brooklyn +13 — Over/Under: +227.5

(Get latest betting odds)

The Cleveland Cavaliers pay a visit to the Brooklyn Nets at the Barclays Center on Friday night. Here’s a Cleveland Cavaliers vs Brooklyn Nets Prediction. This article will include a Cleveland Cavaliers vs Brooklyn Nets Pick.

Cleveland Cavaliers Betting Preview 

The Cleveland Cavaliers will be eager to bounce back in this game after coming up short against the Knicks in a 119-111 road defeat on Wednesday night. Donovan Mitchell led the team with 31 points and five assists on 12 of 25 shooting, Evan Mobley added 22 points, eight rebounds, three assists and three steals while Sam Merrill chipped in with 19 points on six of 11 shooting.

As a team, the Cavaliers shot 46 percent from the field and 19 of 46 from the 3-point line as they exploded for 37 points in the third quarter to take the lead and erase an early 17-point deficit. Only to allow the Knicks to go on a crucial 14-0 run early in the fourth quarter to spoil their comeback. The Cavaliers’ Mitchell just didn’t get enough support from his teammates, with players like Jarrett Allen scoring just four points and Lonzo Ball finishing with just three points on one of seven shooting off the bench. Turnovers were an issue all night and the Cavaliers fell in love with the long ball, which is why they were outscored by 31-12 at the free throw line. 

Brooklyn Nets Betting Preview 

Meanwhile, the Brooklyn Nets might still be nursing their wounds after getting routed by the Hornets in a 136-117 road defeat in their season opener on Wednesday. Nic Claxton led the team with 17 points on eight of 12 shooting, Cam Thomas added 15 points on two of nine shooting, Day’Ron Sharpe and Egor Demin each scored 14 points while Terance Mann chipped in with 13 points.

As a team, the Nets shot just 44 percent from the field and 14 of 40 from the 3-point line as they struggled from the start. They were even worse on the defensive end, as they were never in the contest after allowing 77 points in the first half. With the game over by halftime, the Nets’ coach decided to spread out the playing time, with no player seeing more than 26 minutes.

Why the Brooklyn Nets will win

  • The Cavaliers have lost five of their last six games as favorites against Eastern Conference opponents.
  • The Nets have won seven of their last eight home games against Cavaliers teams that held a losing record.
  • The Cavaliers have failed to cover the spread in each of their last six road games against Atlantic Division opponents after losing as favorites.
  • The Nets have covered the spread in five of their last six night games at Barclays Center following a road loss.

Why the Cleveland Cavaliers will win

  • The Cavaliers have won 19 of their last 20 night games against Eastern Conference opponents that held a losing record.
  • The Nets have lost each of their last eight night games against Central Division opponents.
  • The road team has covered the spread in each of the last six games between the Cavaliers and Nets.
  • The Nets have failed to cover the spread in each of their last six games as home underdogs.

Total Points Facts

  • Each of the Nets’ last nine night games against Central Division opponents have gone UNDER the total points line.
  • Seven of the Cavaliers’ last nine road games against Atlantic Division opponents have gone OVER the total points line.

Cleveland Cavaliers vs Brooklyn Nets Prediction

The Cavaliers are still shorthanded with Darius Garland ruled out again, and they are keeping an eye on De’Andre Hunter who remains with a questionable tag, while the Nets are still missing Haywood Highsmith and Danny Wolf. The Cavaliers will be disappointed with the result in their season opener, but now they’re up against a much more beatable opponent in the Nets, who are coming off a beat down at the hands of the lowly Hornets.

It’s not surprising at all to see the Cavaliers open as heavy road favorites in this matchup, but I still don’t think it’s too high, especially with the Cavaliers coming off a bad loss. I’m sure the Cavaliers come out swinging in this one and make it look easy on their way to their first win of the season against this young Nets squad in a rebuild season.

Peter Tran's Pick: Cleveland -13

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