Yankees vs Orioles Prediction 9/19/2025 Today’s MLB Picks

In this article we will formulate a Yankees vs Orioles prediction for this MLB game on Friday, September 19th at Camden Yards in Baltimore, Maryland. Let’s take a look at the prediction for this MLB matchup. 

New York Yankees Betting Preview

The New York Yankees are 86-67 this year after they won game one by a score of 7-0 on Thursday night. New York jumped out to a 2-0 lead in the first inning and never looked back in the shutout win. The Yankees recorded nine hits in the game and they were led by Stanton and Rosario, who both had two RBIs in the win. New York started Fried, who allowed three hits and zero earned runs over 7.0 innings for the win, while Blackburn closed out the game.

Prior to this series, the Yankees won two out of three against the Twins and two out of three against the Red Sox. New York has won six of their last eight games and they are second in the AL East standings. The New York pitching staff has a 4.03 ERA with a 1.27 WHIP and a .232 opponent batting average, while the offense has scored 801 runs with a .250 batting average and a .331 on base percentage this season. Aaron Judge has led New York with 48 home runs and 104 RBIs, while Cody Bellinger has added 29 home runs and 97 RBIs this year. The projected starting pitcher for New York is Will Warren, who is 8-7 with a 4.44 ERA and a 1.38 WHIP over 152.0 innings pitched this year. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 72-81 this season after they lost game one by a score 7-0 on Thursday night. Baltimore fell behind early in the game and never got their offense going in the blowout loss. The Orioles recorded three hits in the game and they were led by Mountcastle, Henderson, and Mayo, who all had one hit in the loss. Baltimore started Povich, who allowed five hits and three earned runs over 5.0 innings for the loss, while McDermott allowed four earned runs in relief. 

Prior to this series, the Orioles won all three against the White Sox, but lost all three against the Blue Jays before that. Baltimore has won three of their last four games and they are last in the AL East standings. The Baltimore pitching staff has a 4.61 ERA with a 1.37 WHIP and a .260 opponent batting average, while their offense has scored 650 runs with a .238 batting average and a .307 on base percentage this season. Jackson Holliday has led Baltimore with 17 home runs and 55 RBIs, while Gunnar Henderson has added 16 home runs and 64 RBIs this year. The projected starting pitcher for Baltimore is Trevor Rogers, who is 8-2 with a 1.43 ERA and a 0.89 WHIP over 100.2 innings pitched this season. 

Why the Orioles will beat the Yankees

The Yankees have lost seven of their last nine games as favorites against the Orioles following a win.
The Orioles have won six of their last eight games as underdogs against the Yankees following a loss.
The Orioles have covered the run line in 10 of their last 12 games as underdogs against the Yankees following a home loss.
The Yankees have failed to cover the run line in 14 of their last 17 games as favorites against the Orioles following a road win.

Total Runs Facts

Each of the Orioles’ last 10 home games after playing the previous day have gone UNDER the total runs line.
Seven of the Yankees’ last eight games as favorites against AL East opponents have gone UNDER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Yankees’ last eight games.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Orioles’ last four games.

Baltimore Orioles Player Prop Facts

Trevor Rogers has recorded six or more strikeouts in each of his last six appearances with the Orioles as underdogs.
Gunnar Henderson has recorded a hit in each of the Orioles’ last seven games against the Yankees at Oriole Park at Camden Yards.
Tyler O’Neill has hit a home run in four of his last seven home appearances.
Dylan Carlson has recorded a Double in each of his last three appearances with the Orioles as home underdogs against AL East opponents.

New York Yankees Player Prop Facts

Amed Rosario has hit a home run in each of his last two road appearances after playing the previous day.
Amed Rosario has recorded at least one hit in each of his last seven appearances against AL East opponents.
Amed Rosario has recorded a Double in each of his last four appearances against AL East opponents that held a losing record.

Yankees vs Orioles Prediction 

New York comes into this matchup looking to extend their winning streak to four games and they are just three back of the Blue Jays in the East. The Yankees are 42-36 on the road this year, while the Orioles are 36-39 at home. Baltimore has been very up and down recently, but they are starting Rogers, who has allowed a total of five earned runs in his last five starts. New York is going with Warren, who has allowed 6, 2, 2, 0, and 5 earned runs in his last five outings. Rogers has been elite for the O’s this season and I like them to get the win here.