Yankees vs Guardians Prediction 6/10/2026 Today’s MLB Picks

In this article we will formulate a Yankees vs Guardians prediction for this MLB game on Wednesday, June 10th at Progressive Field in Cleveland, Ohio. Let’s take a look at the prediction for this MLB matchup. 

New York Yankees Betting Preview

The New York Yankees are 40-26 this year after they won the first two games in this series by scores of 7-5 and 3-2. In game two, New York blew a 2-0 lead in the third inning, but they scored once in the eighth for the win. The Yankees recorded eight hits and they committed one error in the game, while they were led by Jones, who went 2-4 with one home run and two RBIs. Cole allowed five hits and two earned runs over 4.0 innings, while Doval got the win and Cruz picked up the save. Prior to this series, New York split two games with the Red Sox and lost two out of three against the Guardians.

This season, New York has a 3.25 ERA with a 1.17 WHIP and a .223 opponent batting average, while they have scored 334 runs with a .242 batting average and a .329 on base percentage. Aaron Judge (OUT) has led the Yankees with 17 home runs and 38 RBIs, while Ben Rice has added 18 home runs and 45 RBIs. The projected starting pitcher for New York is Carlos Rodon, who is 1-2 with a 2.88 ERA and a 1.20 WHIP over 25.0 innings pitched this year. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 37-32 this season after they lost game two by a score of 3-2 on Tuesday. Cleveland scored twice in the third inning to tie the game, but they didn’t score in the last six innings in the loss. The Guardians recorded 10 hits and they committed one error, while they were led by DeLauter, who went 1-4 with one RBI in the game. Cecconi allowed six hits and two earned runs over 5.0 innings, while Herrin picked up the loss in relief. Prior to this series, Cleveland lost two out of three against the Rangers, but did win two out of three against the Yankees before that. 

This season, Cleveland has a 3.77 ERA with a 1.26 WHIP and a .238 opponent batting average, while they have scored 279 runs with a .231 batting average and a .317 on base percentage. Chase DeLauter has led the Guardians with seven home runs and 34 RBIs, while Jose Ramirez has added 10 home runs and 33 RBIs. The projected starting pitcher for Cleveland is Parker Messick, who is 6-2 with a 2.40 ERA and a 1.07 WHIP over 75.0 innings pitched this season. 

Why the Cleveland Guardians will win

• The Guardians have won each of their last six Wednesday games.
• The Yankees have lost four of their last five day games at Progressive Field following a win.
• The Yankees have failed to cover the run line in each of their last five day games at Progressive Field following a win.
• The Guardians have covered the run line in five of their last six games against AL East opponents that held a winning record.

Why the New York Yankees will win

• The Yankees have won each of their last seven road games against AL Central opponents.
• The Guardians have lost each of their last four games as favorites against American League opponents.
• The Guardians have failed to cover the run line in each of their last seven games as home favorites.
• The Yankees have covered the run line in each of their last nine Wednesday games as underdogs.

Total Runs Facts

• Ten of the Yankees’ last 12 day games against AL Central opponents have gone UNDER the total runs line.
• Each of the Guardians’ last three games as home favorites have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Guardians’ last five games as favorites against American League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Yankees’ last six games as road underdogs against American League opponents.

Yankees vs Guardians Prediction 

New York comes into this matchup after winning four of their last five games and they are looking to complete the series sweep here. The Yankees are 21-14 on the road this year, while the Guardians are 17-16 at home. Cleveland has lost three in a row and they have allowed 20 runs in those three losses. The Guardians are starting Messick, who has allowed two earned runs or fewer in four of his last five starts, while Rodon has allowed two earned runs or fewer in four straight. Take the under once again here.

David Racey's Pick: Under 8