Ball, Baseball, Baseball (Ball)

White Sox vs Twins Prediction 4/24/25 MLB Picks

Pick details

Minnesota Twins (9-15) vs Chicago White Sox (5-19)

April 24, 2025 at 01:10 PM EDT

The Line: Betting Odds: Minnesota Twins -230 / Chicago White Sox +190 — Over/Under: 8.5

(Get latest betting odds)

In this article, we will formulate a White Sox vs Twins prediction for this MLB game on Thursday, April 24th at Target Field in Minneapolis, Minnesota. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 5-19 this year, and they have lost the first two games in this series by scores of 2-4 and 3-6. In the game two loss, the White Sox scored three runs in the fifth inning to lead 3-2, but they allowed the last four runs for the loss. The White Sox recorded six hits and they committed one error in the game, while they were led by Quero and Benintendi, who both had one RBI in the loss. Chicago started Wilson, who allowed five hits and one earned run over 2.2 innings, while Leasure picked up the loss late in the game. 

Prior to this series, the White Sox lost three out of four against the Red Sox and all three against the Athletics. Chicago has lost nine of their last ten games, and they are currently last in the AL Central standings. The Chicago pitching staff has a 4.35 ERA with a 1.38 WHIP and a .239 opponent batting average, while the offense has scored 75 runs with a .200 batting average and a .275 on-base percentage this season. Andrew Benintendi has led Chicago with four home runs and nine RBIs, while Andrew Vaughn has added three home runs and 10 RBIs this year. The projected starting pitcher for Chicago is Shane Smith, who is 0-1 with a 2.82 ERA and a 0.94 WHIP over 22.1 innings pitched this year. 

Minnesota Twins Betting Preview

The Minnesota Twins are 9-15 this season after they won game two in the series by a score of 6-3. Minnesota jumped out to a 2-0 lead in the fourth inning, but they needed four runs later in the game to get the win. The Twins recorded 12 hits and they committed one error in the game, while they were led by Buxton and Larnach, who both had two RBIs in the win. Minnesota started Festa, who allowed four hits and two earned runs over 4.0 innings, while Topa picked up the win and Coulombe got the save. 

Prior to this series, the Twins lost all three against the Braves, but did win two out of three against the Mets before that. Minnesota has lost three of its last five games, and they are currently fourth in the AL Central standings. The Minnesota pitching staff has a 3.89 ERA with a 1.24 WHIP and a .243 opponent batting average, while their offense has scored 85 runs with a .216 batting average and a .294 on-base percentage this season. Byron Buxton has led Minnesota with five home runs and 12 RBIs, while Harrison Bader has added three home runs and 12 RBIs this year. The projected starting pitcher for Minnesota is Chris Paddack, who is 0-2 with a 7.27 ERA and a 1.56 WHIP over 17.1 innings pitched this season. 

Why the Twins will beat the White Sox 

  • The White Sox have lost each of their last 10 games against AL Central opponents.
  • The Twins have won each of their last 10 games against the White Sox at Target Field following a win.
  • The White Sox have failed to cover the run line in 13 of their last 14 games at Target Field against teams that held a losing record.
  • The Twins have covered the run line each of their last six games at Target Field against AL Central opponents that held a losing record.
  • The Twins have led after 5 innings in five of their last six games at Target Field against AL Central opponents that held a losing record.
  • The White Sox have trailed after 3 innings in seven of their last eight road games.

Total Runs Facts

  • Five of the Twins’ last six games as home favorites have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in 12 of the Twins’ last 13 day games.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the White Sox’s last five day games at Target Field.

White Sox vs Twins Prediction 

Minnesota comes into this game looking to complete the series sweep, which they badly need after a poor start to the season. The Twins are 6-5 at home this year, while the White Sox are 1-11 on the road. Chicago has allowed at least four runs in seven straight games, but they will start Smith, who has pitched very well over his four starts. Minnesota is going with Paddack, who has some ugly numbers on the season, but has allowed just one earned run in each of his last two starts. We took Minnesota -1.5 last night and we are going back to the same thing here. 

David Racey's Pick: Twins -1.5

Need More? Get Premium Picks

Hot Cappers

Latest Picks & Game Previews

  • Indiana State vs Indiana Prediction 9/12/2025 Today’s College Football Picks

    September 12, 2025

  • Colgate vs Syracuse Prediction 9/12/2025 Today’s College Football Picks

    September 12, 2025

  • Colorado vs Houston Prediction 9/12/2025 Today’s College Football Picks

    September 12, 2025

  • Kansas State vs Arizona Prediction 9/12/2025 Today’s College Football Picks

    September 12, 2025

  • New Mexico vs UCLA Prediction 9/12/2025 Today’s College Football Picks

    September 12, 2025

  • Clemson vs Georgia Tech Prediction 9/13/2025 Today’s College Football Picks

    September 13, 2025

  • Houston Christian vs Nebraska Prediction 9/13/2025 Today’s College Football Picks

    September 13, 2025

  • Wisconsin vs Alabama Prediction 9/13/2025 Today’s College Football Picks

    September 13, 2025

  • Oregon vs Northwestern Prediction 9/13/2025 Today’s College Football Picks

    September 13, 2025

  • Buffalo vs Kent State Prediction 9/13/2025 Today’s College Football Picks

    September 13, 2025