White Sox vs Pirates Prediction 07/18/2025 Picks

In this article we will formulate a White Sox vs Pirates prediction for this MLB game on Friday, July 18th at PNC Park in Pittsburgh, Pennsylvania. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 32-65 this year after they lost three out of four against Cleveland by scores of 2-4, 5-4, 2-6, and 5-6. In their game four loss, Chicago led 3-0 in the fifth inning, but they needed a run to tie the game in the eighth, before losing in extras. The White Sox recorded nine hits and they committed one error in the game, while they were led by Slater, who went 2-3 with one home run and two RBIs in the loss. Chicago started Civale, who allowed three hits and four earned runs over 5.2 innings, while Eisert picked up the loss. 

Prior to that series, the White Sox lost two out of three against the Blue Jays, but did win two out of three against the Rockies before that. Chicago has lost six of their last eight games, and they are currently last in the AL Central standings. The Chicago pitching staff has a 4.15 ERA with a 1.38 WHIP and a .251 opponent batting average, while the offense has scored 332 runs with a .220 batting average and a .294 on-base percentage this season. Miguel Vargas has led Chicago with 10 home runs and 35 RBIs, while Andrew Benintendi has added 11 home runs and 35 RBIs this year. The projected starting pitcher for Chicago is Jonathan Cannon, who is 3-7 with a 4.44 ERA and a 1.44 WHIP over 77.0 innings pitched this year. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 39-58 this season after they lost two out of three against Minnesota by scores of 1-2, 4-12, and 2-1. In their game three win, Pittsburgh gave up a 1-0 lead in the third inning, but they were able to escape with a run in the ninth for the victory. The Pirates recorded 10 hits in the game, and they were led by Horwitz and Pham, who both had one RBI in the win. Pittsburgh started Keller, who allowed four hits and one earned run over 6.0 innings, while Santana got the win and Bednar picked up the save. 

Prior to that series, the Pirates lost all three against the Royals and all three against the Mariners. Pittsburgh has lost eight of its last nine games, and they are currently last in the NL Central standings. The Pittsburgh pitching staff has a 3.73 ERA with a 1.20 WHIP and a .234 opponent batting average, while their offense has scored 326 runs with a .230 batting average and a .300 on-base percentage this season. Oneil Cruz has led Pittsburgh with 16 home runs and 37 RBIs, while Bryan Reynolds has added 10 home runs and 46 RBIs this year. The projected starting pitcher for Pittsburgh is Bailey Falter, who is 6-4 with a 3.79 ERA and a 1.20 WHIP over 97.1 innings pitched this season. 

Why the Pirates will beat the White Sox

The White Sox have lost each of their last nine night games against National League opponents following a home loss.
The Pirates have won each of their last seven games at PNC Park.
The White Sox have failed to cover the run line in eight of their last nine night games against National League opponents following a home loss.
The Pirates have covered the run line in six of their last seven games at PNC Park.
The Pirates have led after 3 innings in five of their last six games at PNC Park.
The White Sox have trailed after 5 innings in each of their last five Friday night games against NL Central opponents that held a losing record.

Why the White Sox will beat the Pirates

The Pirates have lost each of their last six night games against American League opponents.
The underdogs have won four of the Pirates’ last six games at PNC Park.
The Pirates have failed to cover the run line in each of their last seven games as home favorites against AL Central opponents following a road win.
The White Sox have covered the run line in seven of their last eight games as road underdogs after going to extra innings.
The White Sox have led after 3 innings in three of their last four night games against NL Central opponents that held a losing record.
The Pirates have trailed after 5 innings in five of their last six home games against AL Central opponents.

Total Runs Facts
Five of the Pirates’ last six games as home favorites have gone UNDER the total runs line.
Four of the White Sox’s last five games after going to extra innings have gone UNDER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Pirates’ last seven games as favorites against American League opponents.
The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the White Sox’s last 11 games as road underdogs against National League opponents.

Pittsburgh Pirates Player Prop Facts
Bryan Reynolds has hit a home run in three of his last seven home appearances after not playing the previous day.
Bryan Reynolds has recorded at least one hit in each of the Pirates’ last 13 home games against AL Central opponents.

Chicago White Sox Player Prop Facts
Miguel Vargas has hit at least one home run in two of the White Sox’s last three road games against NL Central opponents.
Luis Robert has recorded at least one hit in each of his last six appearances against opponents that held a losing record.

Matchup/League Facts
The Pirates rank 30th in the league for doubles this season (126).
The Pirates rank 30th in the league for RBIs this season (315).
The White Sox rank 29th in the league for RBIs this season (317).
The White Sox rank 29th in the league for slugging percentage this season (.344).

White Sox vs Pirates Prediction 

Both teams come into this series sitting at the bottom of their respective divisions, and neither finished the first half with much momentum. Chicago is 11-36 on the road this year, while Pittsburgh is 26-21 at home. The Pirates are starting Falter, who has allowed exactly three earned runs in four of his last five starts. The White Sox are turning to Cannon, who has allowed two earned runs or fewer in three straight starts (13.1 IP). Both of these offenses have been pretty rough this year, and with both pitchers doing decently well, I like the under here.