Mar 28, 2026; Milwaukee, Wisconsin, USA;  Milwaukee Brewers shortstop Joey Ortiz (3) and second baseman Brice Turang (2) celebrate after beating the Chicago White Sox at American Family Field. Mandatory Credit: Benny Sieu-Imagn Images
Benny Sieu-Imagn Images

White Sox vs Brewers Prediction 3/29/2026 Today’s MLB Picks

Pick details

MATCHUP Chicago White Sox Milwaukee Brewers
Team Records 0-2 2-0
Spread +1.5 -149 -1.5 123
Moneyline +144 -175
Total Over 7.5 (-110) Under 7.5 (-110)
Where American Family Field, Milwaukee, Wisconsin
When Sunday, March 29, 2026
Time 02:10 PM EDT
TV MLB.TV

In this article we will formulate a White Sox vs Brewers prediction for this MLB game on Sunday, March 29th at American Family Field in Milwaukee, Wisconsin. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 0-2 this year after they lost game two by a score of 6-1 on Saturday night. Chicago cut the deficit to 4-1 in the fourth inning, but they couldn’t find anymore offense for the loss. The White Sox recorded seven hits and they committed one error, while they were led by Murakami, who went 1-3 with one home run and one RBI in the game. Burke allowed seven hits and three earned runs over 4.0 innings for the loss, while Taylor and Hudson both allowed one earned run in relief. 

Last year, Chicago had a 4.26 ERA with a 1.36 WHIP and a .248 opponent batting average, while they scored 647 runs with a .232 batting average and a .302 on base percentage. Lenyn Sosa led the team with 22 home runs and 75 RBIs, while Andrew Benintendi added 20 home runs and 63 RBIs last year. The projected starting pitcher for Chicago is Anthony Kay, who is 4-2 with a 5.59 ERA and a 1.61 WHIP over 85.1 innings pitched in his career. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 2-0 this season after they won games one and two by scores of 14-2 and 6-1. In game two, Milwaukee scored the first four runs in the game and they cruised to the easy win. The Brewers recorded 12 hits in the game and they were led by Mitchell, who went 2-4 with two RBIs in the win. Patrick allowed five hits and one earned run over 4.1 innings for a no decision, while Ashby picked up the win in relief. 

Last season, Milwaukee had a 3.58 ERA with a 1.23 WHIP and a .230 opponent batting average, while they scored 806 runs with a .258 batting average and a .332 on base percentage. Christian Yelich led the team with 29 home runs and 103 RBIs, while Brice Turang added 18 home runs and 81 RBIs. The projected starting pitcher for Milwaukee is Brandon Sproat, who went 0-2 with a 4.79 ERA and a 1.21 WHIP over 20.2 innings pitched last season. 

Why the Milwaukee Brewers will win

  • The Brewers have won each of their last nine games against American League opponents that held a losing record.
  • The White Sox have lost each of their last eight road games against NL Central opponents that held a winning record.
  • The Brewers have covered the run line each of their last six games against American League opponents that held a losing record.
  • The White Sox have failed to cover the run line in each of their last six games as underdogs against NL Central opponents following a road loss.
  • The White Sox have trailed after 5 innings in each of their last five games against opponents that held a winning record.
  • The Brewers have led after 3 innings in each of their last four games against AL Central opponents.

Why the Chicago White Sox will win

  • The White Sox have won four of their last six games as road underdogs against National League opponents following a loss.
  • The Brewers have lost four of their last five games after playing the previous day.
  • The White Sox have covered the run line in 14 of their last 15 day games against teams that held a winning record.
  • The Brewers have failed to cover the run line in nine of their last 11 games after playing the previous day.

Total Runs Facts

  • Each of the Brewers’ last four games after playing the previous day have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Brewers’ last six games as favorites.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the White Sox’s last nine road games against NL Central opponents.

Milwaukee Brewers Player Prop Facts

  • Andrew Vaughn has recorded a Double in three of his last four appearances against opponents that held a losing record.
  • Gary Sanchez has hit a home run in three of his last five home appearances against opponents that held a losing record.
  • Andrew Vaughn has recorded at least one hit in each of his last nine home appearances against AL Central opponents that held a losing record.

Chicago White Sox Player Prop Facts

  • Andrew Benintendi has hit at least one home run in each of the White Sox’s last two day games against NL Central opponents that held a winning record.
  • Andrew Benintendi has recorded at least one hit in 14 of his last 15 appearances against NL Central opponents that held a winning record.

White Sox vs Brewers Prediction 

Milwaukee has outscored Chicago by a score of 20-3 in the first two games of this series and they are looking for the sweep here. The Brewers are starting Sproat, who only pitched about 20 innings last year. Chicago is going with Kay, who has pitched 85 innings in his MLB career, but his numbers are very underwhelming. I think the pitching matchup is a huge question mark, but we know Milwaukee is seeing the ball well. Take the Brewers to win by at least two runs in this one.

David Racey's Pick: Brewers -1.5

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