Sep 21, 2025; Detroit, Michigan, USA;  Atlanta Braves celebrate after defeating the Detroit Tigers at Comerica Park. Mandatory Credit: Rick Osentoski-Imagn Images

Washington Nationals vs Atlanta Braves Prediction 9/22/2025 Today’s MLB Picks

Pick details

Washington (64-92) vs Atlanta (73-83)

September 22, 2025 at 07:15 PM EDT

The Line: Betting Odds: Atlanta -1.5 — Over/Under: +7

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The Washington Nationals and Atlanta Braves meet Monday in MLB action at Truist Park. Here’s a Washington Nationals vs Atlanta Braves Prediction. This article will include a Washington Nationals vs Atlanta Braves Pick.

Washington Nationals Betting Preview

The Washington Nationals are 64-92 on the year and play the White Sox next. The Washington Nationals are batting .243 on the season, have a .305 OBP, and a .386 slugging percentage. The Washington Nationals pitching staff has a 5.32 ERA and a 1.44 WHIP. James Wood leads the Washington Nationals with 146 hits and 89 RBI, while CJ Abrams and Luis Garcia Jr. have combined for 265 hits and 120 RBI.

MacKenzie Gore gets the ball for the Washington Nationals, and he is 5-14 with a 4.00 ERA and 182 strikeouts this season. Gore is 3-2 with a 2.85 ERA and 41 strikeouts in his career against the Atlanta Braves.

Atlanta Braves Betting Preview

The Atlanta Braves are 73-83 on the year and play the Pirates next. The Atlanta Braves are batting .245 on the season, have a .320 OBP, and a .398 slugging percentage. The Atlanta Braves pitching staff has a 4.37 ERA and a 1.31 WHIP. Matt Olson leads the Atlanta Braves with 167 hits and 93 RBI while Ozzie Albies and Michael Harris II have combined for 286 hits and 154 RBI.

Chris Sale gets the ball for the Atlanta Braves, and he is 5-5 with a 2.35 ERA and 150 strikeouts this season. Sale is 0-2 with a 2.56 ERA and 36 strikeouts in his career against the Washington Nationals.

Washington Nationals @ Atlanta Braves Betting Trends: September 22, 2025

  • Probable Starting Pitcher: Chris Sale      Record this season: 5-5      ERA: 2.35
  • Home Record: 1-2
  • Last 5 against Nationals: 0-2

Why the Atlanta Braves will win

  • The Braves have won each of their last seven games after playing the previous day.
  • The Nationals have lost seven of their last eight games at Truist Park following a road win.
  • The Braves have covered the run line in each of their last eight games following a road win.
  • The Nationals have failed to cover the run line in each of their last five night games against NL East opponents.
  • The Braves have led after 5 innings in each of their last three home games against NL East opponents that held a losing record.
  • The Nationals have trailed after 3 innings in three of their last four games at Truist Park against opponents that held a losing record.
  • Probable Starting Pitcher: MacKenzie Gore      Record this season: 5-14      ERA: 4.00
  • Road Record: 3-8
  • Last 5 against Braves: 2-1

Why the Washington Nationals will win


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  • The Braves have lost each of their last three games as home favorites.
  • The underdogs have won each of the Braves’ last three games.
  • The road team has covered the run line in 11 of the Braves’ last 12 games.
  • The Braves have failed to cover the run line in 10 of their last 12 night games at Truist Park following a win.
  • The Nationals have led after 5 innings in three of their last four games.
  • The Braves have trailed after 3 innings in six of their last eight home games against NL East opponents.

Total Runs Facts

  • Seven of the last eight games between the Nationals and Braves at Truist Park have gone UNDER the total runs line.
  • Each of the Nationals’ last three road games after playing the previous day have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Braves’ last seven home games against NL East opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Nationals’ last eight Monday night games against NL East opponents.

Atlanta Braves Player Prop Facts

  • Matt Olson has hit a home run in five of the Braves’ last six games as favorites against the Nationals.
  • Chris Sale has recorded nine or more strikeouts in six of his last seven appearances.
  • Austin Riley has recorded at least one hit in 14 of his last 15 appearances at Truist Park against NL opponents that held a losing record.
  • Marcell Ozuna has recorded a Double in three of his last four appearances with the Braves as favorites against NL East opponents.

Washington Nationals Player Prop Facts

  • CJ Abrams has hit a home run in each of the Nationals’ last two games at Truist Park against NL East opponents that held a losing record.
  • MacKenzie Gore has recorded five or more strikeouts in seven of his last eight appearances with the Nationals as underdogs against NL East opponents.
  • CJ Abrams has recorded at least one hit in each of his last eight appearances with the Nationals as underdogs against the Braves.
  • Keibert Ruiz has recorded a Double in each of his last three appearances with the Nationals as underdogs against the Braves.

Washington Nationals vs Atlanta Braves Prediction

Neither team has anything to play for, but the Braves are finishing the season strong with 8 straight wins, and that’s good enough for me. Sale has also been dealing when he’s pitched this season, and he’s allowed 14 hits and 4 runs in his last 19.2 innings. Sale has allowed 5 runs in his last 25.2 innings. In 62 at bats against current Nationals, Sale is allowing a .194 batting average with 18 strikeouts. I’ll ride the hot hand and the better pitcher and side with the Braves at home.

Randy Chambers's Pick: Atlanta Braves

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