Texas Rangers vs Cleveland Guardians Prediction 9/27/2025 Today’s MLB Picks

The Texas Rangers and the Cleveland Guardians meet Saturday in MLB action from Progressive Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Texas Rangers vs. Cleveland Guardians prediction.

Starting Pitching Matchup

The Texas Rangers did not have a starting pitcher announced at the time that this article was posted. Cleveland will send out Joey Cantillo here and Cantillo is 5-3 with a 3.21 ERA and 100 strikeouts this season. This will be Cantillo’s first career start against Texas.

Texas Rangers Recap

The Texas Rangers come into this game looking to build on their 7-3 win over Cleveland from Saturday’s matchup to improve to 81-79 this season.

Rangers Trying To Play Spoiler And Guarantee Winning Season

Corey Seager has 103 hits including 21 home runs and 50 RBIs while Adolis Garcia has 113 hits with 28 doubles, 18 home runs, 74 RBIs and 13 stolen bases. Josh Jung has 117 hits with 21 doubles, 14 home runs and 60 RBIs while Wyatt Langford has 118 hits with 25 doubles, 22 home runs, 62 RBIs and 22 stolen bases and Jonah Heim has 11 homers and 43 RBIs. Josh Smith has chipped in 124 hits with 23 doubles, 10 home runs and 35 RBIs with 12 stolen bases and Marcus Semien’s added 108 hits with 16 doubles, 15 homers and 62 RBIs but has 93 strikeouts this season.

Cleveland Guardians Recap

The Cleveland Guardians come into this game looking to rebound from their loss at the hands of Texas in Friday’s opener to drop to 86-74 this season.

Guardians Clinging To AL Central Lead

Steven Kwan has 169 hits as part of a .275 batting average and 11 home runs, 29 doubles and 56 RBIs. Kyle Manzardo has 107 hits with 18 doubles, 2 triples, 26 home runs and 68 RBIs as well this year. Gabriel Arias has 24 doubles but also 157 strikeouts and Manzardo has 132 strikeouts so far this season. Arias has also added 11 home runs and 53 RBIs and Jose Ramirez has chipped in 30 home runs and 85 RBIs with 40 stolen bases as well. 

Texas Rangers @ Cleveland Guardians Betting Trends: September 27, 2025

• Probable Starting Pitcher: Joey Cantillo      Record this season: 5-3      ERA: 3.21
• Home Record: 2-2
• Last 5 against Rangers: –

Why the Cleveland Guardians will win

• The Rangers have lost each of their last nine road games against the Guardians following a road win.
• The Guardians have won nine of their last 10 home games against the Rangers following a home loss.
• The Rangers have failed to cover the run line in each of their last nine road games against the Guardians following a road win.
• The Guardians have covered the run line in nine of their last 10 home games against the Rangers following a home loss.
• The Rangers have trailed after 5 innings in five of their last six road games.
• The Rangers have trailed after 3 innings in six of their last seven games against American League opponents.
• The Rangers have lost the first inning in three of their last four road games.

• Probable Starting Pitcher: TBD

Why the Texas Rangers will win

• The underdogs have won eight of the Rangers’ last nine games.
• The Guardians have lost three of their last four games as favorites.
• The underdogs have covered the run line in eight of the Rangers’ last nine games.
• The Guardians have failed to cover the run line in five of their last six games as favorites following a loss.
• The Guardians have trailed after 5 innings in four of their last five home games against opponents that held a winning record.
• The Guardians have trailed after 3 innings in four of their last five games against opponents that held a winning record.

Total Runs Facts

• Eight of the Guardians’ last nine home games after playing the previous day have gone UNDER the total runs line.
• Each of the Rangers’ last four night games as underdogs have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Rangers’ last seven games against American League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 13 of the last 15 night games between the Rangers and Guardians.

Cleveland Guardians Player Prop Facts

• Lane Thomas has hit a home run in two of his last three appearances in night games against AL teams that held a winning record.
• Will Brennan has recorded at least one Double in each of his last three appearances with the Guardians as favorites against AL opponents.
• Steven Kwan has recorded at least one hit in each of his nine previous Saturday appearances against AL West teams that held a winning record.

Texas Rangers Player Prop Facts

• Josh Jung has recorded at least one hit in each of the Rangers’ last eight games against AL opponents that held a winning record.
• Corey Seager has hit a home run in each of his last two appearances.
• Corey Seager has recorded a Double in three of his last four appearances with the Rangers as underdogs.

Matchup/League Facts

• The Guardians rank 30th in the league for hits this season (1177).
• The Guardians rank 29th in the league for batting average this season (.226).
• The Rangers rank 1st in the league for ERA this season (3.45).
• The Rangers rank 1st in the league for runs allowed this season (590).

Texas Rangers vs. Cleveland Guardians Prediction

I’m on the Guardians here. The Rangers looked really good in Friday’s opener, but the Guardians have not lost back-to-back games in a while. This is a team that normally bounces back this time of year the rare time that they fall down, and I think this is a prime spot for Cleveland to bounce back here. Give me Cleveland in this one.