Aug 16, 2025; San Francisco, California, USA; Tampa Bay Rays designated hitter Yandy Diaz (2) hits an RBI single against the San Francisco Giants during the eighth inning at Oracle Park. Mandatory Credit: Darren Yamashita-Imagn Images

Tampa Bay Rays vs San Francisco Giants Prediction 8/17/2025 Today’s MLB Picks

Pick details

Tampa Bay (61-63) vs San Francisco (59-64)

August 17, 2025 at 04:05 PM EDT

The Line: Betting Odds: San Francisco -157 / Tampa Bay +141 — Over/Under: +7.5

(Get latest betting odds)

In this article, we will formulate a Rays vs Giants Prediction for this MLB game on Sunday, August 17th at the Oracle Park in the third game of this series, with the Rays having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.

San Francisco Giants Preview

The San Francisco Giants have a 59-64 record this season and are sitting on the 4th place of the NL West. They have a 29-33 home record and are 56-62 in over/under. They are coming off a 1-2 home defeat by the Rays, and have seven consecutive losses. Under is 6-2-1 in their last 9 games and are playing the Padres and the Brewers next.

The Giants have a .232 batting average this season, .309 OBP and .373 Slugging percentage. San Francisco’s pitching staff has a 3.72 ERA and 1.29 WHIP. Heliot Ramos leads the Giants with 125 hits and is the team’s best hitter, with a .265 batting average. Willy Adames leads the team in RBI with 62, adding a team-high 19 home runs.

Logan Webb (R) is the projected starting pitcher for the Giants, and he has a 10-9 record, 3.34 ERA and 1.26 WHIP.

Tampa Bay Rays Preview

The Tampa Bay Rays have a 61-63 record this season and are sitting on the 4th place of the AL East. The Rays have a 29-33 road record and are 50-67 in over/under. They are coming off a 2-1 road victory over the Giants, and are 4-1 in their last 5 games. Over is 6-3-1 in their last 10 games and are playing the Yankees and the Cardinals next.

The Rays have a .251 batting average this season, .314 OBP and .400 slugging percentage. Tampa’s pitching staff has a 3.89 ERA and 1.21 WHIP. Yandy Diaz leads the Rays with 132 hits, while Jonathan Aranda is the team’s best hitter with .316 batting average. Junior Caminero leads the team in RBI, with 85 and in home runs, with 35.

Ryan Pepiot (R) is the projected starting pitcher for the Rays, and he has an 8-9 record, 3.86 ERA and 1.18 WHIP.

Why the San Francisco Giants will win

  • The Giants have won each of their last four day games against American League opponents following a home loss.
  • The Rays have lost four of their last five day games following a win.
  • The Rays have failed to cover the run line each of their last four day games against National League opponents that held a losing record.
  • The Giants have covered the run line in four of their last five games against the Rays following a loss.
  • The Giants have won the first inning in three of their last four games as home favorites against AL East opponents.
  • The Giants have led after 3 innings in each of their last four games as home favorites against American League opponents.
  • The Rays have trailed after 5 innings in three of their last four road day games.

Why the Tampa Bay Rays will win

  • The Giants have lost each of their last eight games as home favorites after playing the previous day.
  • The Rays have won each of their last six games as road underdogs against National League opponents following a win.
  • The Giants have failed to cover the run line in each of their last 11 games as home favorites after playing the previous day.
  • The Rays have covered the run line in each of their last seven games as road underdogs against National League opponents following a road win.
  • The Giants have trailed after 3 innings in each of their last four day games.
  • The Giants have trailed after 5 innings in each of their last four day games.

Total Runs Facts

  • Eight of the Giants’ last nine day games against AL East opponents have gone OVER the total runs line.
  • Seven of the Rays’ last eight games against NL West opponents have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Giants’ last six games as home favorites against AL East opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the Rays’ last seven day games.

Matchup/League Facts

  • The Giants rank 1st in the league for home runs allowed this season (107).
  • The Giants rank 29th in the league for steals this season (56).
  • The Rays rank 1st in the league for steals this season (158).
  • The Rays rank 5th in the league for walks allowed this season (352).

Rays vs Giants Prediction

The Rays are 7-2 in their last 9 head-to-head meetings against the Giants, and are 5-1 in their last 5 visits in San Francisco. Over is 3-1 in their last 4 meetings.

In this Rays vs Giants Prediction, the Giants are coming as -165 home favorites. The Giants are in a free fall lately, but they are putting their ace on the mound in Logan Webb, hence the big favoritism in this game. Both pitchers are struggling though, as Webb has a 1-4 record and 5.14 ERA in his last five starts, having given up 4 and 6 runs in two of his last three home starts. Pepiot has also been struggling for the Rays, as he has a 5.79 ERA in his last five starts, and he is weaker on the road, with a 4.34 road ERA. Both teams are better against right-handed pitching, averaging 9.5 runs per game combined. I expect some runs in this game, so take the over 7.5 in this one.

Nikos Lagouretos's Pick: Over 7.5

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