Tampa Bay Rays vs San Francisco Giants Prediction 8/16/2025 Today’s MLB Picks

The Tampa Bay Rays and the San Francisco Giants meet Saturday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Tampa Bay Rays vs. San Francisco Giants prediction.

Starting Pitching Matchup

The Tampa Bay Rays will send out Adrian Houser for the start here and Houser is 6-4 with a 2.84 ERA and 54 strikeouts this season. In his career, Houser is 1-0 with a 1.54 ERA and 10 strikeouts against the Giants. Justin Verlander will get the start for the Giants here and is 1-9 with a 4.53 ERA and 87 strikeouts this season. In his last five starts against the Rays, Verlander is 2-2 with a 4.03 ERA and 34 strikeouts.

Tampa Bay Rays Recap

The Tampa Bay Rays come into this game looking to add on to their 7-6 win over the Giants from Friday’s series opener to sit at 60-63 this season. After this series, the Rays will go back home for a division series against the rival New York Yankees.

Rays Win Back-To-Back Games

Jonathan Aranda has 113 hits with 22 doubles, 12 home runs and 54 RBIs. Brandon Lowe has 103 hits with 24 homers and 59 RBIs as well while Junior Caminero has 119 hits with 21 doubles, a team-high 34 home runs and 84 RBIs. Yandy Diaz has 128 hits with 22 doubles, 20 homers and 67 RBIs.

Why the Tampa Bay Rays will win

• The Giants have lost each of their last eight games as home favorites after playing the previous day.
• The Rays have won each of their last 12 night games against NL West opponents that held a losing record.
• The Giants have failed to cover the run line in each of their last 11 home games after playing the previous day.
• The Rays have covered the run line in each of their last seven games as road underdogs against National League opponents following a road win.

Tampa Bay Rays Player Prop Facts

• Yandy Diaz has recorded at least one hit in 31 of his last 33 appearances in night games against teams that held a losing record.
• Adrian Houser has recorded five or more strikeouts in four of his last five appearances against NL opponents.
• Josh Lowe has recorded a Double in three of his last four appearances in night games against teams that held a losing record.
• Adrian Houser has recorded a win in three of his last four appearances against NL opponents.
• Brandon Lowe has hit a home run in five of the Rays’ last seven night games.
• Chandler Simpson ranks T3rd in the league in Steals (34) this season.

San Francisco Giants Recap

The San Francisco Giants come into this one looking to rebound from their loss at the hands of the Rays in Friday’s clash to fall to 59-63 this season. After this series, the Giants will take to the road for a series rematch against the rival San Diego Padres.

Giants Lose 6 Straight

Jung Hoo Lee has 111 hits including a team-high 27 doubles along with 10 triples, 6 home runs and 46 RBIs with 8 stolen bases while Heliot Ramos has 124 hits with 20 doubles, 14 home runs and 51 RBIs. Wilmer Flores also 12 home runs and 61 RBIs while Tyler Fitzgerald has a team-high 9 stolen bases as well on the year. Matt Chapman also has 79 hits with 16 home runs and 44 RBIs along with 15 doubles and Willy Adames has 100 hits with 18 doubles, 18 home runs and 61 RBIs of his own this season.

Why the San Francisco Giants will win

• The Rays have lost six of their last seven night games following a road win.
• The Giants have won five of their last six home games against American League opponents that held a losing record.
• The favorites have covered the run line in five of the Rays’ last six games.
• The Rays have failed to cover the run line in five of their last six games as underdogs after playing the previous day.

San Francisco Giants Player Prop Facts

• Rafael Devers has recorded a Double in three of the Giants’ last four games as favorites against AL opponents.
• Willy Adames has hit at least one home run in five of his last six appearances against AL East opponents that held a losing record.
• Dominic Smith has recorded at least one hit in each of his last 11 appearances with the Giants as favorites.
• Justin Verlander has recorded six or more strikeouts in eight of his last nine appearances against AL East opponents that held a losing record.

Total Runs Facts

• Seven of the Giants’ last eight games as favorites against AL East opponents have gone OVER the total runs line.
• Six of the Rays’ last seven games against NL West opponents have gone UNDER the total runs line.

Tampa Bay Rays vs. San Francisco Giants Prediction

I’m on the Rays here. I tried to give the Giants the benefit of the doubt in a lot of Verlander’s starts this season, only to have it come back and blow up square in my face and I’m past it. The Rays have still been showing some fight despite falling out of the race in the AL East and Wild Card, but I still think there’s enough here to back the Rays at the reasonable price here. I just don’t trust the Giants to take advantage of the shaky form from Adrian Houser, so I’ll roll with Tampa Bay here.