Sep 24, 2025; Baltimore, Maryland, USA; Tampa Bay Rays second baseman Richie Palacios (1) scores during the second inning on a hit by catcher Hunter Feduccia (not shown) against the Baltimore Orioles at Oriole Park at Camden Yards. Mandatory Credit: Mitch Stringer-Imagn Images

Tampa Bay Rays vs Baltimore Orioles Prediction 9/25/2025 Today’s MLB Picks

Pick details

Tampa Bay (77-81) vs Baltimore (74-84)

September 25, 2025 at 01:05 PM EDT

The Line: Betting Odds: Baltimore +1.5 — Over/Under: +8.5

(Get latest betting odds)

The Tampa Bay Rays and Baltimore Orioles meet Thursday in MLB action at Oriole Park at Camden Yards. Here’s a Tampa Bay Rays vs Baltimore Orioles Prediction. This article will include a Tampa Bay Rays vs Baltimore Orioles Pick.

Tampa Bay Rays Betting Preview


The Tampa Bay Rays are 77-81 on the year and play the Blue Jays next. The Tampa Bay Rays are batting .251 on the season, have a .313 OBP, and a .402 slugging percentage. The Tampa Bay Rays pitching staff has a 3.85 ERA and a 1.21 WHIP. Yandy Diaz leads the Tampa Bay Rays with 173 hits and 83 RBI, while Junior Caminero and Brandon Lowe have combined for 281 hits and 192 RBI.

Drew Rasmussen gets the ball for the Tampa Bay Rays, and he is 10-5 with a 2.80 ERA and 124 strikeouts this season. Rasmussen is 2-1 with a 2.97 ERA and 27 strikeouts in his career against the Baltimore Orioles.

Baltimore Orioles Betting Preview


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The Baltimore Orioles are 74-84 on the year and play the Yankees next. The Baltimore Orioles are batting .236 on the season, have a .305 OBP, and a .394 slugging percentage. The Baltimore Orioles pitching staff has a 4.57 ERA and a 1.36 WHIP. Gunnar Henderson leads the Baltimore Orioles with 153 hits and 67 RBI while Jackson Holliday and Jordan Westburg have combined for 223 hits and 92 RBI.

Cade Povich gets the ball for the Baltimore Orioles, and he is 3-8 with a 5.06 ERA and 114 strikeouts this season. This will be Povich’s first career game against the Tampa Bay Rays.

Tampa Bay Rays vs Baltimore Orioles Prediction


The Rays and Orioles have nothing to play for so it’s about motivation and figuring out which team is excited to show up. With that said, Rasmussen has been solid this season even on the road where he has a 2.95 ERA and .217 allowed batting average. Povich isn’t scaring anybody with his 5.06 ERA and 1.46 WHIP, and he has allowed 17 hits and 9 runs in his last 15.2 innings. In 62 home innings, Povich has a 5.66 ERA and .284 allowed batting average. No, thanks. The Rays have the edge on the mound, so that’s the direction I’ll lean.

Randy Chambers's Pick: Tampa Bay Rays


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