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St. Louis Cardinals vs Tampa Bay Rays Prediction 8/24/2025 Today’s MLB Picks
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St. Louis (64-66) vs Tampa Bay (62-67)
August 24, 2025 at 12:10 PM EDT
The Line: Betting Odds: Tampa Bay -1.5 — Over/Under: +9
The St. Louis Cardinals and Tampa Bay Rays meet Sunday in MLB action at George M. Steinbrenner Field. Here’s a St. Louis Cardinals vs Tampa Bay Rays Prediction. This article will include a St. Louis Cardinals vs Tampa Bay Rays Pick.
St. Louis Cardinals Betting Preview
The St. Louis Cardinals are 64-66 on the year and play the Pirates, Reds, and Athletics next. The St. Louis Cardinals are batting .250 on the season, have a .318 OBP, and a .387 slugging percentage. The St. Louis Cardinals pitching staff has a 4.28 ERA and a 1.30 WHIP. Brendan Donovan leads the St. Louis Cardinals with 118 hits and 45 RBI, while Alec Burleson and Masyn Winn have combined for 232 hits and 105 RBI.
Matthew Liberatore gets the ball for the St. Louis Cardinals, and he is 6-10 with a 4.13 ERA and 93 strikeouts this season. This will be Liberatore’s second career game against the Tampa Bay Rays.
Tampa Bay Rays Betting Preview
The Tampa Bay Rays are 62-67 on the year and play the Guardians, Nationals, and Mariners next. The Tampa Bay Rays are batting .251 on the season, have a .314 OBP, and a .400 slugging percentage. The Tampa Bay Rays pitching staff has a 4.03 ERA and a 1.22 WHIP. Yandy Diaz leads the Tampa Bay Rays with 135 hits and 73 RBI while Junior Caminero and Jonathan Aranda have combined for 236 hits and 141 RBI.
Ryan Pepiot gets the ball for the Tampa Bay Rays, and he is 8-10 with a 3.95 ERA and 146 strikeouts this season. This will be Pepiot’s first career game against the St. Louis Cardinals.
Why the Tampa Bay Rays will win
- The Cardinals have lost each of their last seven day games against AL East opponents.
- The Cardinals have failed to cover the run line in seven of their last eight day games following a loss.
- The favorites have covered the run line in four of the Rays’ last five games at George M. Steinbrenner Field.
- The Rays have won the first inning in each of their last three games against NL Central opponents that held a losing record.
- The Rays have led after 3 innings in three of their last four games as home favorites against NL Central opponents.
- The Rays have led after 5 innings in three of their last four home games against opponents that held a losing record.
Why the St. Louis Cardinals will win
- The Cardinals have won four of their last five games as underdogs following a road loss.
- The Rays have lost three of their last four games as home favorites following a win.
- The Rays have failed to cover the run line in each of their last eight day games against National League opponents following a home win.
- The Cardinals have covered the run line in each of their last five games following a road loss.
- The Rays have trailed after 5 innings in three of their last four games.
- The Rays have trailed after 3 innings in three of their last four day games against NL Central opponents that held a losing record.
Tampa Bay Rays Player Prop Facts
- Josh Lowe has recorded a Double in three of his last four appearances with the Rays as favorites.
- Yandy Diaz has hit a home run in three of his last four appearances at George M. Steinbrenner Field against opponents that held a losing record.
- Ha-Seong Kim has recorded at least one hit in each of his last six appearances against NL opponents that held a losing record.
- Junior Caminero ranks 6th in the league in Home Runs (36) this season.
St. Louis Cardinals Player Prop Facts
- Willson Contreras has hit a home run in each of the Cardinals’ last three road games against opponents that held a losing record.
- Willson Contreras has recorded at least one hit in 16 of his last 17 appearances against AL opponents.
St. Louis Cardinals vs Tampa Bay Rays Prediction
I’m not excited to get behind either of these teams that have been shaky over the last few weeks. However, Pepiot has struggled this month, allowing 16 hits and 10 earned runs in his last 17.2 innings. Liberatore has a 3.73 ERA and .253 allowed batting average in 62.2 road innings, which is much better than his home splits. Also, Liberatore was drafted by the Rays in the first round of the 2018 draft, so there should be some motivation here for the 25-year-old. I’ll take a stab with the Cardinals on the road.