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St. Louis Cardinals vs Milwaukee Brewers Prediction 6/13/25 MLB Picks

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Milwaukee Brewers (37-33) vs St. Louis Cardinals (36-33)

June 13, 2025 at 08:10 PM EDT

The Line: Betting Odds: Milwaukee Brewers -157 / St. Louis Cardinals +128 — Over/Under: 7.5

(Get latest betting odds)

The Saint Louis Cardinals are visiting the Milwaukee Brewers on Friday, June 13th at the American Family Field in the second game of this series, with the Brewers having the 1-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Saint Louis Cardinals vs Milwaukee Brewers Prediction. We will examine:

The Milwaukee Brewers’ recent form and player performance

The Saint Louis Cardinals’ recent form and player performance

Recent betting trends and streaks involving the Milwaukee Brewers

Recent betting trends and streaks involving the Saint Louis Cardinals

Recent betting trends in games played between the Saint Louis Cardinals vs Milwaukee Brewers

A summary that ties it all together and produces a favorable betting outcome for the Saint Louis Cardinals vs Milwaukee Brewers game

Milwaukee Brewers Preview

The Milwaukee Brewers have a 37-33 record this season and are sitting in second place in the NL Central. They have a 21-14 home record and are 26-41 in over/under. They are coming off a 6-0 home victory over the Cardinals, and are 2-3 in their last 5 games. Under is 7-3 in their last 10 games, and are playing the Cubs and the Twins next.

The Brewers have a .236 batting average this season, a .313 OBP, and a .363 Slugging percentage. Milwaukee’s pitching staff has a 3.80 ERA and 1.30 WHIP.  Jackson Churio leads the Brewers with 76 hits, while Christian Yelich leads the team in RBI, with 41, and a team-high 13 home runs. Sal Frelick is the team’s best hitter with a .292 batting average.

Freddy Peralta (R) is the projected starting pitcher for the Brewers, and he has a 5-4 record, 2.69 ERA, and 1.16 WHIP. He has been excellent at home, with a 1.29 ERA across six home starts, and he is coming off a shutout start against the Padres in 6 innings pitched. Freddy Peralta is 4-6 with an ERA of 4.91 and 85 strikeouts in 19 appearances against the Cardinals in his career.

Saint Louis Cardinals Preview

The Saint Louis Cardinals have a 36-33 record this season and are sitting in third place in the NL Central. The Cardinals have a 14-19 road record and are 37-30 in over/under. They are coming off a 0-6 road defeat by the Brewers and have five consecutive losses. Over is 6-4 in their last 10 games, and they are playing the White Sox and the Reds next.

The Cardinals have a .256 batting average this season, a .326 OBP, and a .392 Slugging percentage. Saint Louis’ pitching staff has a 3.98 ERA and 1.28 WHIP. Brendan Donovan leads the Cardinals with 77 hits and a team-high .310 batting average, while Wilson Contreras leads the team in RBI, with 43.

Erick Fedde (R) is the projected starting pitcher for the Cardinals, and he has a 3-5 record, 3.54 ERA, and 1.30 WHIP. He has been better on the road, with a 2.88 ERA across six road starts, and he is coming off a shutout start against the Dodgers in 5.1 innings pitched. He got torched in his previous start against the Brewers this season, having given up 7 runs in 5.2 innings of work. Erick Fedde is 2-3 with an ERA of 5.88 and 25 strikeouts in 7 appearances against the Brewers in his career.

Why the Milwaukee Brewers will win

  • The Brewers have won each of their last six night games following a home win.
  • The Cardinals have lost each of their last five games.
  • The Cardinals have failed to cover the run line each of their last five games against teams that held a winning record.
  • The Brewers have covered the run line in each of their last four games against the Cardinals.
  • The Brewers have led after 3 innings in each of their last five games against NL Central opponents.
  • The Brewers have won the first inning in three of their last four games as favorites against NL Central opponents.
  • The Cardinals have trailed after 5 innings in seven of their last eight night games against opponents that held a winning record.

Why the St. Louis Cardinals will win

  • The Cardinals have won nine of their last 10 games as underdogs against NL Central opponents following a road loss.
  • The Brewers have lost each of their last three games as home favorites against National League opponents following a win.
  • The Brewers have failed to cover the run line in each of their last eight home games against National League opponents following a win.
  • The Cardinals have covered the run line in each of their last six road games following a road loss.
  • The Cardinals have won the first inning in five of their last six games as road underdogs against NL Central opponents.
  • The Cardinals have led after 5 innings in four of their last five games as road underdogs against NL Central opponents.
  • The Cardinals have led after 3 innings in four of their last five games as road underdogs against NL Central opponents.

Total Runs Facts

  • Seven of the Brewers’ last eight night games against National League opponents have gone UNDER the total runs line.
  • Five of the Cardinals’ last six road games against National League opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Brewers’ last nine home games.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Cardinals’ last eight games as road underdogs against NL Central opponents.

Matchup/League Facts

  • The Brewers rank 2nd in the league for steals this season (86).
  • The Brewers rank 28th in the league for slugging percentage this season (.363).
  • The Cardinals rank 29th in the league for strikeouts this season (484).
  • The Cardinals rank 3rd in the league for walks allowed this season (187).

Saint Louis Cardinals vs Milwaukee Brewers Prediction

The Cardinals are 6-3 in their last 9 meetings against the Brewers, and are 2-1 in their last 3 visits in Milwaukee, but both teams are tied 2-2 wins this season. Under is 4-1 in their last 5 meetings.

In this Saint Louis Cardinals vs Milwaukee Brewers Prediction, the Brewers are coming as -150 home favorites. Both teams have almost identical overall records, but the Brewers have been strong at home, while the Cardinals are struggling on the road. The Cardinals have been in terrible form lately, and got shut out yesterday by 6-0, and are now putting Fedde on the mound, who has terrible underlying metrics, with a 5.28 expected ERA. On the other hand, Peralta has been excellent for the Brewers, and he’s playing even better at home, so the home team has a huge pitching advantage here. I expect the Brewers to be up front while those two pitchers are on the mound, so take the Milwaukee Brewers on the moneyline in the first 5 innings.

Nikos Lagouretos's Pick: Milwaukee Brewers F5 ML

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