Seattle Mariners vs San Diego Padres Prediction 4/14/2026 Today’s MLB Picks

The Seattle Mariners and the San Diego Padres meet Tuesday in MLB action from Petco Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Seattle Mariners vs. San Diego Padres prediction.

Starting Pitching Matchup

The Seattle Mariners will send out Bryan Woo for the start here and Woo is 0-1 with a 1.50 ERA and 17 strikeouts this season. In his career, Woo is 3-0 with a 2.33 ERA and 16 strikeouts against the Padres. Michael King will get the start for the Padres here and King is 1-1 with a 3.24 ERA and 15 strikeouts this season. In his career, King is 0-3 with a 2.76 ERA and 23 strikeouts against Seattle.

Seattle Mariners Recap

The Seattle Mariners come into this game looking to add on to their 6-2 win over Houston last time out to sit at 8-9 this season. After this series, the Mariners will head home for a series against the Texas Rangers.

Mariners Win 4 In A Row

Entering Monday’s matchup, Brendan Donovan has 12 hits with 2 doubles, 3 home runs and 6 RBIs while Luke Raley has 3 home runs and 9 RBIs this season. Cole Young’s added 14 hits with 2 doubles, a triple, 2 home runs and 8 RBIs and Cal Raleigh has 8 hits with 2 doubles, 2 home runs and 10 RBIs as well this season. Randy Arozarena has 16 hits with 3 doubles, a home run and 7 RBIs as well on the year.

San Diego Padres Recap

The San Diego Padres come into this game looking to add on to their 7-2 win over Colorado last time out to sit at 10-6 this season. After this series, the Padres will head on the road for a set against the Los Angeles Angels.

Padres Win 5 Straight & 8 Of Last 9

Going into Sunday’s series finale, Jackson Merrill has 11 hits with 3 doubles, 2 home runs and 10 RBIs while Ramon Laureano has 14 hits with 3 doubles, 3 home runs and 9 RBIs as well on the year. Fernando Tatis Jr. has 13 hits with 4 doubles and 6 RBIs and Xander Bogaerts has 13 hits with 2 doubles, 2 home runs and 8 RBIs. Manny Machado also has 9 hits with 2 doubles, 2 home runs and 7 RBIs as well on the year.

Seattle Mariners @ San Diego Padres Betting Trends: April 14, 2026

• Probable Starting Pitcher: Michael King      Record this season: 1-1      ERA: 3.24
• Home Record: 0-0
• Last 5 against Mariners: 0-3

Why the San Diego Padres will win

• The home team has won each of the Mariners’ last nine games.
• The Mariners have lost each of their last five games as road favorites after playing the previous day.
• The Mariners have failed to cover the run line in 10 of their last 11 games against National League opponents that held a winning record.
• The Padres have covered the run line in eight of their last nine games.
• The Padres have led after 5 innings in each of their last five games against opponents that held a losing record.
• The Padres have won the first inning in four of their last five games as underdogs against the Mariners at Petco Park.
• The Mariners have trailed after 3 innings in six of their last seven night games against National League opponents that held a winning record.

• Probable Starting Pitcher: Bryan Woo      Record this season: 0-1      ERA: 1.50
• Road Record: 0-1
• Last 5 against Padres: 3-0

Why the Seattle Mariners will win

• The Mariners have won each of their last seven games at Petco Park against teams that held a winning record.
• The Padres have lost each of their last six games against the Mariners following a win.
• The Mariners have covered the run line each of their last seven games at Petco Park against teams that held a winning record.
• The Padres have failed to cover the run line in seven of their last eight home games against American League opponents that held a losing record.
• The Padres have trailed after 5 innings in nine of their last 10 night games against American League opponents that held a losing record.
• The Mariners have won the first inning in each of their last four games.
• The Padres have trailed after 3 innings in each of their last four night games against American League opponents that held a losing record.

Total Runs Facts

• Each of the last four games between the Mariners and Padres at Petco Park have gone UNDER the total runs line.
• Six of the Mariners’ last seven road games have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the Padres’ last 11 games as home underdogs against AL West opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the Mariners’ last nine games.

San Diego Padres Player Prop Facts

• Jake Cronenworth has hit a home run in each of the Padres’ last two games as home underdogs against AL West opponents.
• Fernando Tatis Jr. has recorded at least one hit in each of his last 10 home appearances against the Mariners.

Seattle Mariners Player Prop Facts

• Cal Raleigh has hit at least one home run in three of the Mariners’ last four games as road favorites against NL West opponents.
• Brendan Donovan has recorded at least one hit in each of his last eight appearances against NL opponents.

Matchup/League Facts

• The Padres rank T2nd in the league for home runs allowed this season (10).
• The Padres rank 3rd in the league for doubles this season (34).
• The Mariners rank 1st in the league for walks allowed this season (37).
• The Mariners rank 2nd in the league for ERA this season (2.95).

Seattle Mariners vs. San Diego Padres Prediction

I’m on the Mariners here. between two teams that are hitting well right now and have solid bullpens, I think that Bryan Woo is the better starting option in this one and ultimately I think the Mariners get the job done in this one. Give me Seattle.

Chris Ruffolo's Pick: Seattle -115