Seattle Mariners vs Philadelphia Phillies Prediction 8/20/2025 Today’s MLB Picks

The Seattle Mariners and the Philadelphia Phillies meet Wednesday in MLB action from Citizens Bank Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Seattle Mariners vs. Philadelphia Phillies prediction.

Starting Pitching Matchup

The Seattle Mariners will send out Luis Castillo here and Castillo is 8-6 with a 3.48 ERA and 125 strikeouts this season. In his career, Castillo is 1-1 with a 2.75 ERA and 21 strikeouts against the Phillies. Jesus Luzardo will get the start for the Phillies and is 11-6 with a 4.21 ERA and 158 strikeouts this season. In his career, Luzardo is 1-1 with a 6.14 ERA and 15 strikeouts against Seattle.

Seattle Mariners Recap

The Seattle Mariners come into this game looking to rebound from their 6-4 loss at the hands of the Phillies in Tuesday’s matchup to sit at 68-59 this season. After this series, the Mariners will head home for a series against the Athletics.

Mariners Lose 4 In A Row

Jorge Polanco has 87 hits including 18 home runs and 54 RBIs while Cal Raleigh has 115 hits with 18 doubles, a team-high 47 home runs and 102 RBIs. Randy Arozarena has 113 hits with 24 doubles, 23 home runs, 58 RBIs and 24 stolen bases. Julio Rodriguez also has 133 hits with 22 doubles, 4 triples, 24 home runs, 69 RBIs and 23 stolen bases. Dylan Moore has 9 homers and 12 stolen bases as well this season. J.P Crawford has 118 hits with 17 doubles, 9 home runs and 44 RBIs.

Why the Seattle Mariners will win

• The Mariners have won five of their last seven games as underdogs.
• The Phillies have lost each of their last four Wednesday games as favorites.
• The Phillies have failed to cover the run line in seven of their last eight day games against American League opponents following a home win.
• The Mariners have covered the run line in five of their last six day games against National League opponents following a loss.

Seattle Mariners Player Prop Facts

• Cal Raleigh has hit at least one home run in three of his last four appearances in day games against NL teams that held a winning record.
• Luis Castillo has recorded five or more strikeouts in 17 of his last 18 appearances against NL East opponents.
• J.P. Crawford has recorded a Double in four of his five previous appearances against the Phillies after playing the previous day.
• Victor Robles has recorded at least one hit in each of his last 10 appearances in day games.
• Luis Castillo has recorded a win in three of his last four appearances against NL East opponents.
• Cal Raleigh ranks 1st in the league in Home Runs (47) this season.

Philadelphia Phillies Recap

The Philadelphia Phillies come into this game looking to build on their win over the Mariners from Tuesday to improve to 73-53 this season. After this series, the Phillies will have a division series rematch set up with the Washington Nationals.

Phillies Win Three Straight

Nick Castellanos has 117 hits with 24 doubles including 16 home runs and 61 RBIs while Kyle Schwarber has 114 hits with a team-high 43 home runs and 102 RBIs but also has a team-high 150 strikeouts as well on the year. Bryce Harper has 10 stolen bases, 28 doubles, 19 home runs and 55 RBIs. Trea Turner also has 147 hits with 4 triples, 12 home runs, 52 RBIs and a team-high 28 stolen bases. Max Kepler has 16 doubles and Bryson Stott has 15 doubles, 3 triples, 7 homers and 47 RBIs while Stott also has 19 stolen bases as well this season.

Why the Philadelphia Phillies will win

• The Phillies have won eight of their last nine games against American League opponents.
• The Mariners have lost each of their last four games.
• The Phillies have covered the run line each of their last six games against American League opponents that held a winning record.
• The Mariners have failed to cover the run line in nine of their last 10 games against National League opponents.

Philadelphia Phillies Player Prop Facts

• J.T. Realmuto has hit a home run in each of the Phillies’ last two games as favorites.
• Jesus Luzardo has recorded seven or more strikeouts in five of his last six home appearances.
• J.T. Realmuto has recorded at least one hit in each of his last 10 home appearances against AL West opponents.
• Jesus Luzardo has recorded a win in each of his last three appearances against AL opponents.
• J.T. Realmuto has recorded a Double in six of the Phillies’ last seven day games against opponents that held a winning record.
• Trea Turner ranks 2nd in the league in Hits (152) this season.

Total Runs Facts

• Eleven of the Mariners’ last 12 games against NL East opponents have gone OVER the total runs line.
• Each of the Phillies’ last five home games against AL West opponents have gone OVER the total runs line.

Seattle Mariners vs. Philadelphia Phillies Prediction

I’m backing the Phillies here. I get the case that you could make for Seattle as Luzardo has had his issues at times this season. However, Philadelphia continues to be the better team while the Mariners are just falling apart right now, losing 4 straight and 6 of 7. The Mariners need to just get back home, but they don’t have that luxury right now and I just think that the Phillies find a way to get the job done here as well. Give me Philadelphia.