Seattle Mariners vs Los Angeles Angels Prediction 6/6/25 MLB Picks

The Seattle Mariners are visiting the Los Angeles Angels on Friday, June 6th at the Angel Stadium in the opening game of this series. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Seattle Mariners vs Los Angeles Angels Prediction. We will examine:

The Los Angeles Angels’ recent form and player performance

The Seattle Mariners’ recent form and player performance

Recent betting trends and streaks involving the Los Angeles Angels

Recent betting trends and streaks involving the Seattle Mariners

Recent betting trends in games played between the Seattle Mariners vs Los Angeles Angels

A summary that ties it all together and produces a favorable betting outcome for the Seattle Mariners vs Los Angeles Angels game

Los Angeles Angels Preview

The Los Angeles Angels have a 28-33 record this season and are sitting in 4th place in the AL West. The Angels have a 10-15 home record and 33-28 in over/under. They are coming off a 9-11 road defeat by the Red Sox, which ended their previous two-game winning streak. Under is 7-3 in their last 10 games, and are playing the Athletics and the Orioles next.

The Angels have a .226 batting average this season, a .288 OBP, and a .405 Slugging percentage. LA’s pitching staff has a 4.88 ERA and 1.52 WHIP. Nolan Schanuel leads the Angels with 56 hits, and he is the team’s best hitter with a .275 batting average. Taylor Ward leads the team with 42 RBI and a team-high 17 home runs.

Kyle Hendricks (R) will take the mound for the Angels, and he has a 2-6 record, 5.34 ERA, and 1.29 WHIP. He has been better at home with a 3.80 ERA across four home starts, and he has given up 3+ runs in seven of his last eight starts. In his only previous meeting against the Mariners back in 2019, he gave up one run in 6 innings of work.    

Seattle Mariners Preview

The Seattle Mariners have a 32-29 record this season and are sitting in second place in the AL West. The Mariners have a 16-12 road record and 32-26 in over/under. They are coming off a 3-4 home defeat by the Orioles, and are on a three-game losing streak. Under is 3-0-1 in their last 4 games, and they are playing the Diamondbacks and the Guardians next.

The Mariners have a .236 batting average this season, a .318 OBP, and a .392 Slugging percentage. Seattle’s pitching staff has a 3.87 ERA and 1.32 WHIP. Julio Rodriguez leads the Mariners in hits with 60, while Cal Raleigh leads the team both in RBI with 49 and in home runs with 24. J.P. Crawford is the team’s best hitter with a .283 batting average.

Bryce Miller (R) will take the mound for the Mariners, and he has a 2-4 record, 5.36 ERA, and 1.53 WHIP. He has been bad on the road, with a 5.68 ERA across four road starts, and he has given up 3+ runs in four of his last five starts. His previous start against the Angels this season was a shutout in 5 innings pitched.  

Why the Los Angeles Angels will win

• The Mariners have lost seven of their last eight games as favorites after playing the previous day.
• The Angels have won each of their last four games as underdogs against AL West opponents.
• The Mariners have failed to cover the run line in each of their last 10 games as favorites after playing the previous day.
• The underdogs have covered the run line in each of the Mariners’ last eight games.
• The Angels have led after 5 innings in five of their last six games.
• The Angels have led after 3 innings in five of their last six games.

Why the Seattle Mariners will win

• The Angels have lost each of their last nine night games against AL West opponents that held a winning record.
• The Mariners have won eight of their last nine road games against AL West opponents following a home loss.
• The Angels have failed to cover the run line each of their last nine night games against AL West opponents that held a winning record.
• The Mariners have covered the run line in 12 of their last 13 games as road favorites following a home loss.
• The Angels have trailed after 5 innings in each of their last five home games.
• The Mariners have won the first inning in three of their last four games as road favorites against American League opponents.
• The Angels have trailed after 3 innings in seven of their last eight games against AL West opponents that held a winning record.

Total Runs Facts

• Each of the Angels’ last five home games have gone UNDER the total runs line.
• Eight of the Mariners’ last 10 road games have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Mariners’ last nine Friday games at Angel Stadium of Anaheim.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the Angels’ last seven home games against American League opponents.

Matchup/League Facts

• The Angels rank 30th in the league for walks allowed this season (256).
• The Angels rank 29th in the league for steals this season (25).
• The Mariners rank 29th in the league for doubles this season (74).
• The Mariners are one of only three teams in the league to rank top 10 in both steals and home runs this season.

Seattle Mariners vs Los Angeles Angels Prediction

The Angels are 7-3 in their last 10 overall meetings against the Mariners, and are 4-1 in their last 5 meetings in LA. Over is 4-1 in their last 5 meetings.

In this Seattle Mariners vs Los Angeles Angels Prediction, the Mariners are coming as -150 road favorites. The Mariners have a better overall record and have been good on the road, while the Angels have been struggling at home, hence them being big road favorites. But Seattle’s recent form has been terrible, as they are coming off a home series sweep by the Orioles, where they scored 6 runs in three games, and they are putting Bryce Miller on the mound, who has been struggling this season. I don’t trust Hendricks for the Angels either, as both pitchers have a 5+ ERA. With both teams being better against right-handed pitching, I expect a high-scoring game. Take the over 9.5 runs.