Sep 19, 2025; Los Angeles, California, USA;  Los Angeles Dodgers shortstop Mookie Betts (left) celebrates with center fielder Andy Pages (44) after hitting a solo home run during the fifth inning against the San Francisco Giants at Dodger Stadium. Mandatory Credit: Kiyoshi Mio-Imagn Images

San Francisco Giants vs Los Angeles Dodgers Prediction 9/20/2025 Today’s MLB Picks

Pick details

San Francisco (76-77) vs Los Angeles (86-67)

September 20, 2025 at 09:10 PM EDT

The Line: Betting Odds: Los Angeles -1.5 — Over/Under: +8.5

(Get latest betting odds)

The San Francisco Giants and Los Angeles Dodgers meet Saturday in MLB action at Dodger Stadium. Here’s a San Francisco Giants vs Los Angeles Dodgers Prediction. This article will include a San Francisco Giants vs Los Angeles Dodgers Pick.

San Francisco Giants Betting Preview


The San Francisco Giants are 76-78 on the year and play the Cardinals and Rockies next. The San Francisco Giants are batting .235 on the season, have a .311 OBP, and a .385 slugging percentage. The San Francisco Giants pitching staff has a 3.82 ERA and a 1.30 WHIP. Heliot Ramos leads the San Francisco Giants with 149 hits and 61 RBI, while Jung Hoo Lee and Willy Adames have combined for 265 hits and 134 RBI.

Kai-Wei Teng gets the ball for the San Francisco Giants, and he is 2-4 with a 6.41 ERA and 33 strikeouts this season. This will be Teng’s first career game against the Los Angeles Dodgers.

Los Angeles Dodgers Betting Preview


The Los Angeles Dodgers are 87-67 on the year and play the Diamondbacks and Mariners next. The Los Angeles Dodgers are batting .254 on the season, have a .329 OBP, and a .440 slugging percentage. The Los Angeles Dodgers pitching staff has a 4.03 ERA and a 1.27 WHIP. Shohei Ohtani leads the Los Angeles Dodgers with 165 hits and 98 RBI while Freddie Freeman and Andy Pages have combined for 310 hits and 166 RBI.

Tyler Glasnow gets the ball for the Los Angeles Dodgers, and he is 3-3 with a 3.06 ERA and 96 strikeouts this season. Glasnow is 4-1 with a 3.12 ERA and 32 strikeouts in his career against the San Francisco Giants.

San Francisco Giants @ Los Angeles Dodgers Betting Trends: September 20, 2025


  • Probable Starting Pitcher: Tyler Glasnow      Record this season: 3-3      ERA: 3.06
  • Home Record: 2-2
  • Last 5 against Giants: 3-1

Why the Los Angeles Dodgers will win

  • The Dodgers have won eight of their last nine games against NL West opponents.
  • The Giants have lost each of their last five night games against NL West opponents.
  • The Dodgers have covered the run line each of their last four home games against teams that held a losing record.
  • The Giants have trailed after 5 innings in three of their last four games at Dodger Stadium against opponents that held a winning record.

  • Probable Starting Pitcher: Kai-Wei Teng      Record this season: 2-4      ERA: 6.41
  • Road Record: 1-3
  • Last 5 against Dodgers: –

Why the San Francisco Giants will win

  • The Dodgers have lost each of their last three Saturday games as favorites.
  • The Giants have covered the run line in six of their last seven road games against National League opponents that held a winning record.
  • The Dodgers have failed to cover the run line in four of their last five home games against the Giants following a win.

Total Runs Facts

  • The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the Giants’ last seven night games.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in nine of the Dodgers’ last 11 night games at Dodger Stadium.

Matchup/League Facts

  • The Dodgers rank 2nd in the league for walks this season (557).
  • The Dodgers rank 2nd in the league for strikeouts this season (1397).
  • The Giants rank 28th in the league for doubles this season (225).
  • The Giants rank 26th in the league for hits this season (1193).

San Francisco Giants vs Los Angeles Dodgers Prediction


The Giants are playing their way out of the playoff race as the losses continue to pile up. I doubt Teng can turn things around with his 6.41 ERA and 1.61 WHIP. The Dodgers are closing in on a NL West title and Glasnow is finding his form, allowing 3 hits and 2 runs in his last 13.2 innings. In 56.2 home innings, Glasnow has a 2.38 ERA and .159 allowed batting average. I have to roll with the Dodgers yet again, and of course, I’ll lay the RL to shave down the juice.

Randy Chambers's Pick: Los Angeles Dodgers -1.5

Hot Cappers

Latest Picks & Game Previews

  • UAB vs Tennessee Prediction 9/20/2025 Today’s College Football Picks

    September 20, 2025

  • Wagner vs Central Michigan Prediction 9/20/2025 Today’s College Football Picks

    September 20, 2025

  • Braves vs Tigers Prediction 9/20/2025 Today’s MLB Picks

    September 20, 2025

  • Cleveland Guardians vs Minnesota Twins Prediction 9/20/2025 Today’s MLB Picks

    September 20, 2025

  • Brentford FC Brentford FC vs Fulham Fulham Prediction 9/20/2025 Today’s EPL Picks

    September 20, 2025

  • Oregon State vs Oregon Prediction 9/20/2025 Today’s College Football Picks

    September 20, 2025

  • Purdue vs Notre Dame Prediction 9/20/2025 Today’s College Football Picks

    September 20, 2025

  • James Madison vs Liberty Prediction 9/20/2025 Today’s College Football Picks

    September 20, 2025

  • Toledo vs Western Michigan Prediction 9/20/2025 Today’s College Football Picks

    September 20, 2025

  • North Carolina vs UCF Prediction 9/20/2025 Today’s College Football Picks

    September 20, 2025