San Francisco Giants vs Cleveland Guardians Prediction 06/19/2025 Picks

TheCleveland Guardians are visiting the San Francisco Giants on Thursday, June 19^th at the Oracle Park in the third game of this series, with the Guardians having the 2-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cleveland Guardians vs San Francisco Giants Prediction. We will examine:
The San Francisco Giants recent form and player performance
The Cleveland Guardians recent form and player performance
Recent betting trends and streaks involving the San Francisco Giants
Recent betting trends and streaks involving the Cleveland Guardians
Recent betting trends in games played between the Cleveland Guardians vs San Francisco Giants
A summary that ties it all together and produces a favorable betting outcome for the Cleveland Guardians vs San Francisco Giants game

San Francisco Giants Preview

The San Francisco Giants have a 41-33 record this season and are sitting on the second place of the NL West. They have a 22-13 home record and are 34-38 in over/under. They are coming off a 2-4 home defeat by the Guardians, and are 1-5 in their last 6 games. Over is 4-2-1 in their last 6 games, and are playing the Red Sox and the Marlins next.

The Giants have a .233 batting average this season, .312 OBP and .375 Slugging percentage. San Francisco’s pitching staff has a 3.26 ERA and 1.22 WHIP.  Heliot Ramos leads the Giants with 78 hits and is the team’s best hitter, with a .284 batting average. Wilmer Flores leads the team in RBI with 51, while Matt Chapman leads the team in home runs, with 12.

Logan Webb (R) is the projected starting pitcher for the Giants, and he has a 6-5 record, 2.58 ERA and 1.12 WHIP. He has been better at home, with a 1.36 ERA across seven home starts, and he has given up 2 runs or less in his last three starts. This will be his first career start versus the Guardians.

Cleveland Guardians Preview

The Cleveland Guardians have a 37-35 record this season and are sitting on the third place of the AL Central. The Guardians have a 18-20 road record and are 33-36 in over/under They are coming off a 4-2 road victory over the Giants, and have back-to-back wins. They are playing the Blue Jays and the Athletics next.

The Guardians have a .231 batting average this season, .303 OBP and .374 Slugging percentage. Cleveland’s pitching staff has a 3.93 ERA and 1.38 WHIP. Jose Ramirez leads the Guardianswith 84 hits and a team-high .319 batting average, while leading the team in home runs, with 13. Carlos Santana leads the team in RBI, with 35.

Gavin Williams (R) is the projected starting pitcher for the Guardians, and he has a 5-3 record, 3.89 ERA and 1.47 WHIP. He has been weaker on the road with a 4.40 ERA across six road starts, and he has given up 2+ runs in three of his last four starts. In his only start against the Giants back in 2023, he gave up three runs across 6 innings pitched.  

Why the San Francisco Giants will win

The Guardians have lost eight of their last nine day games against NL West opponents that held a winning record.
The Giants have won each of their last four day games following a home loss.
The Guardians have failed to cover the run line in eight of their last nine day games against NL West opponents.
The Giants have covered the run line in five of their last six day games against American League opponents following a loss.
The Guardians have trailed after 3 innings in three of their last four games.
The Guardians have trailed after 5 innings in each of their last seven road day games.

Why the Cleveland Guardians will win

The Giants have lost eight of their last nine games as favorites against AL Central opponents.
The underdogs have won eight of the Giants’ last 10 games at Oracle Park.
The underdogs have covered the run line in each of the Giants’ last 14 games at Oracle Park.
The Giants have failed to cover the run line in each of their last 11 games as home favorites.
The Giants have trailed after 3 innings in six of their last seven home games against American League opponents that held a winning record.
The Giants have lost the first inning in each of their last three games against opponents that held a winning record.
The Giants have trailed after 5 innings in each of their last five games against American League opponents that held a winning record.

Total Runs Facts

Each of the Giants’ last six games as home favorites have gone UNDER the total runs line.
Each of the Guardians’ last five road games against National League opponents have gone UNDER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Guardians’ last six games at Oracle Park.
The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the Giants’ last nine games.

Matchup/League Facts

The Giants rank 2nd in the league for home runs allowed this season (57).
The Giants rank 3rd in the league for ERA this season (3.26).
The Guardians rank 29th in the league for hits this season (541).
The Guardians rank 26th in the league for doubles this season (99).

Cleveland Guardians vs San Francisco Giants Prediction

The Guardians have won their last four meetings against the Giants, but the Giants are 4-2 in their last 6 meetings in San Francisco. Both of their meetings this season went under the total, with 5 and 6 total runs.  
In this Cleveland Guardians vs San Francisco Giants Prediction, the Giantsare coming as -180 road favorites. The Giantsare rightfully favored, as they have a better overall record, and have been strong at home, while the Guardians are below average on the road. The Giants have the best bullpen in the league, and are putting their ace on the mound in Logan Webb, who has been excellent this season and almost unhittable at home, with a 1.36 home ERA. Gavin Williams has been good for the Guardians, but he is weaker on the road and has an expected ERA of 4.54. the Giants also have a better offense and are much better against right-handed pitching, so I expect them to get the job done at home today.