San Diego Padres vs Los Angeles Dodgers Prediction 06/18/2025 Picks

In this article, we will formulate a Padres vs Dodgers prediction for this MLB game on Wednesday, June 18, at Dodger Stadium in Los Angeles, California. Let’s take a look at the prediction for this MLB matchup.

San Diego Padres Betting Preview

The San Diego Padres (39-33, 18-21 Away) lost back-to-back series to the Los Angeles Dodgers and Arizona Diamondbacks, and will not win the current four-game series against the Dodgers after suffering a couple of losses. Following a 6-3 loss, the Padres succumbed to an 8-6 defeat on Tuesday and have now lost five of the previous six games. Gavin Sheets and Trenton Brooks led the offense with two RBI apiece, while Randy Vasquez pitched for 5.0 innings in a no-decision, allowing three runs on four hits with two strikeouts and no walks. Jeremiah Estrada took the loss.

This season, the Padres average 4.20 runs per game (17th in the MLB) on a .248/.314/.378 triple-slash. When it comes to pitching, the Padres’ staff has a 3.53 ERA (8th) and 1.21 WHIP (10th). Manny Machado leads the Padres with a .316 batting average, 11 home runs, and 45 RBI this season.

Stephen Kolek will take the mound for the Padres on Wednesday. The 28-year-old right-hander has a 3-2 record in eight starts this year with a 3.50 ERA and 1.32 WHIP in 46.1 innings.

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers (45-29, 27-12 Home) responded to a series loss to the St. Louis Cardinals with victories over the Padres and Giants. The Dodgers will at least split the current series against the Padres after winning the first two games, 6-3 and 8-6. In last night’s Game 2 victory, Andy Pages led the offense with a couple of home runs and three RBI, while Matt Sauer was credited with the win in what was the bullpen day for the Dodgers.

This year, the Dodgers average 5.55 runs per game (1st in the MLB) on a .264/.340/.457 triple-slash. When it comes to pitching, the Dodgers’ staff has a 4.17 ERA (22nd) and 1.31 WHIP (20th). Teoscar Hernandez leads the Dodgers with a .263 batting average, 13 home runs, and 50 RBI this season.

The projected starting pitcher for the Dodgers is Emmet Sheehan, who will get his first start since 2023.

Why the Padres will cover

The Padres have won four of their last five games as road underdogs against the Dodgers following a road loss.
The Dodgers have lost four of their last six games as home favorites against the Padres following a home win.
The Padres have covered the run line in nine of their last 10 games against National League opponents following a road loss.
The Dodgers have failed to cover the run line in seven of their last eight Wednesday night games as home favorites against NL West opponents.
The Dodgers have lost the first inning in three of their last four night games against NL West opponents.
The Dodgers have trailed after 3 innings in six of their last eight night games against National League opponents that held a winning record.

Total Runs Facts

Each of the Dodgers’ last six night games against National League opponents have gone OVER the total runs line.
Each of the Padres’ last four games against NL West opponents have gone OVER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in 11 of the Dodgers’ last 12 home games.
The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Padres’ last six night games against NL West opponents.

Matchup/League Facts

The Dodgers rank 1st in the league for home runs this season (115).
The Dodgers rank 1st in the league for RBIs this season (397).
The Padres rank 4th in the league for opponent batting average this season (.227).
The Padres rank 5th in the league for hits allowed this season (540).

Padres vs Dodgers Prediction

The Dodgers won seven of the previous ten H2H encounters, including six of the last seven, while this season, the Dodgers lead 4-1. The hosts will start Emmet Sheehan, who is coming off the IL and hasn’t pitched since 2023. I am not sure how many innings he will stay on the mound on Wednesday, but the Padres will get to him and score multiple runs. Stephen Kolek, on the other hand, surrendered only four runs in his last three starts and is pitching way better in June than in May. I don’t think he’ll get a quality start in this one, but he should keep the Padres close. I am going with San Diego to cover a +1.5 run line.