San Diego Padres vs Arizona Diamondbacks Prediction 08/06/2025 Today’s MLB Picks

In this article, we will formulate a San Diego Padres vs Arizona Diamondbacks Prediction for this MLB game on Wednesday, August 6^th at the Chase Field in the third game of this series, with both teams being tied 1-1 wins. Let’s take a look at the prediction for this MLB matchup.

Arizona Diamondbacks Preview

The Arizona Diamondbacks have a 54-60 record this season and are sitting on the 4^th place of the NL West. The Diamondbacks have a 27-29 home record and are 54-52 in over/under They are coming off a 5-10 home defeat by the Padres, which ended their previous three-game winning streak. Under is 10-2-2 in their last 14 games and are playing the Rangers and the Rockies next.

The Diamondbacks have a .249 batting average this season, .325 OBP and .437 slugging percentage. Arizona’spitching staff has a 4.58 ERA and 1.34 WHIP. Geraldo Perdomo leads the Diamondbacks with 115 hits, while Josh Naylor is the team’s best hitter with a .292 batting average. Eugenio Suarez leads the team in RBI, with 87 and in home runs with 36.

Anthony DeSclafani (R) is the projected starting pitcher for the Diamondbacks, and he has a 1-2 record, 4.91 ERA and 1.29 WHIP.

San Diego Padres Preview

The San Diego Padres have a 63-51 record this season and are sitting on the second place of the NL West. They have a 27-32 road record, and are 47-64 in over/under. The Padres are coming off a 10-5 road victory over the Dbacks, and are 8-2 in their last 10 games. Over is 3-1 in their last 4 games and are playing the Red Sox and the Giants next. 

The Padres have a .251 batting average this season, .320 OBP and .381 Slugging percentage. San Diego’s pitching staff has a 3.59 ERA and 1.21 WHIP.  Manny Machado leads the Padres with 133 hits and team-high .302 batting average. He also leads the team in RBI, with 72, adding a team-high 20 home runs. 

Nestor Cortes (L) will take the mound for the Padres, and he has a 1-1 record, 9.00 ERA and 1.75 WHIP.

Why the Arizona Diamondbacks will win

• The Padres have lost each of their last five games as road favorites against National League opponents following a win.
• The Diamondbacks have won each of their last four games as underdogs against the Padres following a loss.
• The Padres have failed to cover the run line in each of their last six games as favorites following a road win.
• The underdogs have covered the run line in seven of the last eight games between the Padres and Diamondbacks.
• The Diamondbacks have led after 3 innings in six of their last seven games against National League opponents that held a winning record.
• The Diamondbacks have led after 5 innings in seven of their last eight home games.
• The Padres have lost the first inning in each of their last four road games against National League opponents that held a losing record.

Why the San Diego Padres will win

• The Diamondbacks have lost seven of their last eight games against teams that held a winning record.
• The Padres have won nine of their last 11 games after going to extra innings.
• The Diamondbacks have failed to cover the run line in each of their last seven night games at Chase Field following an extra innings loss.
• The Padres have covered the run line in six of their last seven games against National League opponents after going to extra innings.

Total Runs Facts

• Each of the Diamondbacks’ last eight home games following an extra innings loss have gone OVER the total runs line.
• Eight of the Padres’ last 10 games as favorites against NL West opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Padres’ last six games as road favorites against NL West opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Diamondbacks’ last six night games.

Matchup/League Facts

• The Diamondbacks rank 2nd in the league for triples this season (27).
• The Diamondbacks rank 4th in the league for slugging percentage this season (.437).
• The Padres rank T1st in the league for hits allowed this season (852).
• The Padres rank 29th in the league for home runs this season (96).

San Diego Padres vs Arizona Diamondbacks Prediction

The Dbacks are 6-4 in their last 10 head-to-head meetings against the Padres, andare 5-4 in their 9 meetings this season. They are 5-2 in their last 7 home meetings against the Padres and over is 5-3 in their last 8 meetings.

In this San Diego PadresvsArizona DiamondbacksPrediction, the Padresare coming as -150 home favorites. The Padres have a better overall record, but both teams have exactly 27 home/away wins. DeSclafani has been terrible for the Dbacks this season, and even weaker at home, with a 5.56 home ERA. He is also coming in terrible form, having given up 4 earned runs in his last three starts, and the Dbacks are weaker against left-handed pitching, while the Padres are better against righties, and also boast the best bullpen in the league. Take the San Diego Padres to get the job done on the road tonight.