May 28, 2026; Boston, Massachusetts, USA; Boston Red Sox starting pitcher Payton Tolle (70) pitches against the Atlanta Braves during the first inning at Fenway Park. Mandatory Credit: Eric Canha-Imagn Images
Eric Canha-Imagn Images

Red Sox vs Orioles Prediction 9/6/2026 Today’s MLB Picks

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MATCHUP Boston Red Sox Baltimore Orioles
Team Records 78-65 69-74
Spread -1.5 123 +1.5 -149
Moneyline -136 +113
Total Over 7.5 (-118) Under 7.5 (-102)
Where Oriole Park at Camden Yards, Baltimore, Maryland
When Sunday, September 6, 2026
Time 01:35 PM EDT
TV MLB.TV

In this article we will formulate a Red Sox vs Orioles prediction for this MLB game on Sunday, September 6th at Camden Yards in Baltimore, Maryland. Let’s take a look at the prediction for this MLB matchup. 

Boston Red Sox Betting Preview

The Boston Red Sox are 78-65 this year after they won the first three games by scores of 6-5, 1-0, and 5-0. In game three, Boston scored three runs in the sixth inning and two in the seventh in the win. The Red Sox recorded nine hits in the game and they were led by White, who went 1-4 with two RBIs. Gray allowed three hits and zero earned runs over 7.0 innings for the win, while Olds threw a scoreless inning in relief. Prior to this series, Boston lost two out of three against the Mariners and three out of four against the Yankees. 

This season, Boston has a 3.62 ERA with a 1.24 WHIP and a .242 opponent batting average, while they have scored 639 runs with a .249 batting average and a .323 on base percentage. Willson Contreras has led the Red Sox with 26 home runs and 79 RBIs, while Jarren Duran has added 19 home runs and 68 RBIs. The projected starting pitcher for Boston is Payton Tolle, who is 8-6 with a 3.23 ERA and a 1.10 WHIP over 131.0 innings pitched this year. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 69-74 this season after they lost game three by a score of 0-5 last night. Baltimore pitched pretty well for most of the night, but couldn’t find any offense in the shutout loss. The Orioles recorded five hits and they were led by Henderson, who went 1-2 in the game. Bassitt allowed five hits and three earned runs over 5.2 innings for the loss, while Suarez allowed two earned runs in relief. Prior to this series, Baltimore lost two out of three against the Rockies, but did sweep the Athletics before that. 

This season, Baltimore has a 4.16 ERA with a 1.34 WHIP and a .254 opponent batting average, while they have scored 640 runs with a .234 batting average and a .316 on base percentage. Pete Alonso has led the Orioles with 33 home runs and 94 RBIs, while Gunnar Henderson has added 22 home runs and 57 RBIs. The projected starting pitcher for Baltimore is Kyle Bradish, who is 7-12 with a 4.01 ERA and a 1.42 WHIP over 148.0 innings pitched this season. 

Why the Baltimore Orioles will win

  • The Orioles have won eight of their last 10 day games against AL opponents following a home loss.
  • The Red Sox have lost six of their last eight Sunday day games as favorites against AL opponents.
  • The Red Sox have failed to cover the run line in seven of their last eight games as favorites.
  • The underdogs have covered the run line in six of the Red Sox’s last seven games.

Why the Boston Red Sox will win

  • The Orioles have lost each of their last eight games against the Red Sox at Oriole Park at Camden Yards following a loss.
  • The Red Sox have won each of their last seven road games against the Orioles following a win.
  • The Orioles have failed to cover the run line in four of their last five games as home underdogs following a home loss.
  • The Red Sox have covered the run line in three of their last four day games against AL East opponents that held a losing record.

Total Runs Facts

  • Six of the Orioles’ last seven games as underdogs against AL East opponents have gone UNDER the total runs line.
  • Six of the Red Sox’s last seven day games against AL East opponents have gone UNDER the total runs line.
  • There has been at least one run scored in the first inning in eight of the last nine games between the Red Sox and Orioles.
  • There has been at least one run scored in the first inning in four of Payton Tolle’s last five road appearances as a starter.

Baltimore Orioles Player Prop Facts

  • Kyle Bradish has recorded five or more strikeouts in nine of his last 10 appearances at Oriole Park at Camden Yards against AL opponents that held a winning record.
  • Gunnar Henderson has recorded at least one hit in each of the Orioles’ last six games as underdogs against the Red Sox.
  • Colton Cowser has hit a home run in each of the Orioles’ last three day games against AL opponents that held a winning record.

Boston Red Sox Player Prop Facts

  • Trevor Story has hit a home run in four of his last eight appearances with the Red Sox as road favorites against the Orioles.
  • Payton Tolle has recorded seven strikeouts in three of his last four appearances with the Red Sox as road favorites.
  • Payton Tolle has recorded a win in each of his last three road appearances against AL opponents.
  • Ceddanne Rafaela has recorded at least one hit in 17 of his last 18 road appearances against opponents that held a losing record.

Red Sox vs Orioles Prediction 

Boston comes into this matchup looking to complete the four game sweep and they have shutout the Orioles in back to back games. The Red Sox are 43-31 on the road this year, while the Orioles are 34-37 at home. Baltimore has lost five in a row and they have allowed 5+ runs in three of their last four. The Orioles are starting Bradish, who has allowed 2, 7, 3, and 2 earned runs in his last four starts, while Tolle has allowed two earned runs or fewer in three of his last five outings. Take the over here.

David Racey's Pick: Over 7.5

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