Pittsburgh Pirates vs Texas Rangers Prediction 4/22/2026 Today’s MLB Picks

The Pittsburgh Pirates and the Texas Rangers meet Wednesday in MLB action from Globe Life Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Pittsburgh Pirates vs. Texas Rangers prediction.

Starting Pitching Matchup

The Pittsburgh Pirates will start Braxton Ashcraft here and Ashcraft is 1-1 with a 2.38 ERA and 27 strikeouts this season. Jack Leiter will start this one for the Rangers and is 1-1 with a 4.87 ERA and 24 strikeouts this season. 

Pittsburgh Pirates Recap

The Pittsburgh Pirates come into this game looking to shake off a 5-1 loss at the hands of the Rangers last time out to slip to 13-11 this season. After this series, the Pirates will head on the road for a series against the Milwaukee Brewers.

Pirates Alternate Wins & Losses In 10 Straight

Going into Tuesday, Oneil Cruz has 26 hits including 5 doubles, 6 home runs and 19 RBIs while Ryan O’Hearn has 23 hits with 3 doubles, 4 home runs and 15 RBIs this season. Nick Gonzales has 17 hits with 3 doubles and 11 RBIs while Brandon Lowe has 20 hits with 4 doubles, 7 home runs and 18 RBIs and Bryan Reynolds has 21 hits with a double, a triple, 3 home runs and 15 RBIs as well this season.

Texas Rangers Recap

The Texas Rangers come into this game looking to add on to their win over Pittsburgh from Tuesday to improve to 12-11 this season. After this series, the Rangers will take on the Athletics in a series at home.

Rangers Snap Two-Game Slide

Entering Tuesday’s matchup, Brandon Nimmo has 28 hits with 5 doubles, a triple, 4 home runs and 11 RBIs while Jake Burger has 22 hits with 4 doubles, 5 home runs and 17 RBIs. Corey Seager has 15 hits with 5 home runs and 12 RBIs while Wyatt Langford has 19 hits with 3 doubles, 2 triples, a home run and 4 RBIs. Evan Carter also has 12 hits with 4 doubles, 2 home runs and 6 RBIs while Josh Jung has 20 hits with 7 doubles, 2 home runs and 8 RBIs as well on the year.

Pittsburgh Pirates @ Texas Rangers Betting Trends: April 22, 2026

• Probable Starting Pitcher: Jack Leiter      Record this season: 1-1      ERA: 4.87
• Home Record: 0-0
• Last 5 against Pirates: 0-1

Why the Texas Rangers will win

• The Rangers have won each of their last six games as home underdogs.
• The Pirates have lost six of their last seven games as favorites against AL West opponents following a road loss.
• The Rangers have covered the run line in each of their last 12 games as underdogs following a home win.
• The Pirates have failed to cover the run line in six of their last seven games as favorites against AL West opponents following a road loss.
• The Rangers have led after 5 innings in each of their last six games as home underdogs.
• The Rangers have led after 3 innings in each of their last four games against the Pirates.

• Probable Starting Pitcher: Braxton Ashcraft      Record this season: 1-1      ERA: 2.38
• Road Record: 0-1
• Last 5 against Rangers: 0-0

Why the Pittsburgh Pirates will win

• The Pirates have won each of their last eight games following a loss.
• The Rangers have lost six of their last seven home games against National League opponents.
• The Pirates have covered the run line in each of their last eight games following a loss.
• The Rangers have failed to cover the run line in seven of their last eight night games against the Pirates following a win.
• The Rangers have lost the first inning in five of their last six games as underdogs.
• The Pirates have led after 5 innings in each of their last six Wednesday night games as favorites.
• The Pirates have led after 3 innings in each of their last five games against opponents that held a winning record.

Total Runs Facts

• Each of the Rangers’ last 12 home games have gone UNDER the total runs line.
• Each of the Pirates’ last seven night games against American League opponents have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Rangers’ last six games as underdogs.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Pirates’ last nine games as favorites against AL West opponents.

Texas Rangers Player Prop Facts

• Joc Pederson has hit at least one home run in two of his last three appearances with his team as an underdog against the Pirates.
• Brandon Nimmo has recorded at least one hit in each of his last nine appearances against the Pirates after playing the previous day.

Pittsburgh Pirates Player Prop Facts

• Bryan Reynolds has hit a home run in each of the Pirates’ last two games as road favorites.
• Brandon Lowe has recorded at least one hit in each of his last 11 appearances in night games against AL West teams that held a winning record.
• Oneil Cruz ranks T2nd in the league in Steals (10) this season.

Matchup/League Facts

• The Rangers rank 5th in the league for runs allowed this season (83).
• The Rangers rank 24th in the league for strikeouts against this season (219).
• The Pirates are one of only four teams in the league to rank top 10 in both steals and batting average this season.
• The Pirates rank 4th in the league for ERA this season (3.31).

Pittsburgh Pirates vs. Texas Rangers Prediction

I’m on the Pirates in this one. I just think that Ashcraft is the far better option here and for my money is probably the #2 in this Pirates rotation behind Paul Skenes. Leiter for me is a fringe starter in this Ranger rotation and I think the Pirates get to him enough to get the win here. Give me the Pirates.

Chris Ruffolo's Pick: Pittsburgh -110