Jun 17, 2025; Detroit, Michigan, USA;  Pittsburgh Pirates outfielder Oneil Cruz (15) runs to first after hitting a single in the fourth inning against the Detroit Tigers at Comerica Park. Mandatory Credit: Rick Osentoski-Imagn Images
Rick Osentoski-Imagn Images

Pittsburgh Pirates vs Detroit Tigers Prediction 9/27/2026 Today’s MLB Picks

Pick details

MATCHUP Pittsburgh Pirates Detroit Tigers
Team Records 81-80 76-85
Spread -1.5 128 +1.5 -155
Moneyline -135 +112
Total Over 8 (-107) Under 8 (-112)
Where Comerica Park, Detroit, Michigan
When Sunday, September 27, 2026
Time 03:10 PM EDT
TV MLB.TV

The Pittsburgh Pirates and the Detroit Tigers will meet Saturday afternoon in an interleague matchup at Comerica Park in Detroit, Michigan. Let’s take a look at this matchup from a betting perspective.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates enter Saturday’s contest with an 81-80 overall record (3rd in the National League Central) and a 37-43 mark on the road. The Pirates arrive at this contest in below average. More specifically, Pittsburgh has lost three of the team’s last four games, including a 5-1 loss to the St. Louis Cardinals four days ago.

The Pirates will turn to right hander Jared Jones in this game. In 20 starts made in 2026, Jones has compiled a 5-6 win-loss record, a 3.87 ERA, a 1.12 WHIP and 118 strikeouts in 97.2 innings pitched. Jared Jones has pitched exceptionally well recently, allowing no earned runs in three of his last four starts made this season. Jones will look to continue his recent success on the mound in today’s matchup with the Tigers.

Shifting our focus to the Pittsburgh offense, the Pirates lineup features Bryan Reynolds and Oneil Cruz. Reynolds has amassed a .261 batting average, 17 home runs, 72 RBIs, 40 doubles and a .789 OPS. Cruz has compiled 20 home runs, 67 RBIs, 14 doubles, 30 stolen bases and an .854 OPS.                                                                 

Detroit Tigers Betting Preview

The Detroit Tigers enter Monday’s contest with a 76-85 overall record (4th in the American League Central) and a 42-38 mark at home. The Tigers arrive at tomorrow evening’s game in above average form, winning the team’s last two games, including a thrilling 8-7 victory over the Pittsburgh Pirates two days ago.

The Tigers will start right hander River Ryan in this contest. In one start made in 2026, Ryan allowed no earned runs while scattering two hits and one walk across three innings pitched in the Detroit Tigers 9-2 victory over the Washington Nationals earlier this month. Riley will look to build on his first start of the 2026 campaign.

The Detroit Tigers lineup features catcher Dillon Dingler and outfielder Riley Greene. Dingler has amassed a team leading 27 home runs, 26 doubles, 91 RBIs and a .749 OPS. Greene enters this contest with a .282 batting average (19th in MLB), 21 home runs, 75 RBIs and an .850 OPS.                           

Why the Pittsburgh Pirates will win.

• Starting pitching. In 20 starts made in 2026, Jared Jones has compiled a 5-6 win-loss record, a 3.87 ERA, a 1.12 WHIP and 118 strikeouts in 97.2 innings pitched.

• Motivation. The Pittsburgh Pirates have lost three of the team’s last four games.

• Offensive balance. Bryan Reynolds and Oneil Cruz have been key contributors for the Pittsburgh Pirates in 2026.  

Why the Detroit Tigers will win.

• Home field advantage. The Detroit Tigers have played good baseball at home, amassing a 42-38 win-loss record at Comerica Park.

• Current form. The Detroit Tigers arrive at this contest on the heels of a two-game winning streak.

• Offensive stability. Talented catcher Dillon Dingler has amassed a team leading 27 home runs, 26 doubles, 91 RBIs and a .749 OPS.

• Starting pitching. Detroit will start River Ryan in this matchup.

Pittsburgh Pirates vs. Detroit Tigers Prediction

In my view, this matchup favors the Pittsburgh Pirates. Why? Pittsburgh starting pitcher Jared Jones has pitched exceptionally well recently, allowing no earned runs in three of his last four starts made this season. Conversely, Detroit hurler River Ryan is relatively untested having only started one contest in 2026. With that said, Pittsburgh is the side to be on in this contest. I am backing the Pittsburgh Pirates on the moneyline in this game.

Hans Geevers's Pick: Pittsburgh Pirates ML

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