Pittsburgh Pirates vs Baltimore Orioles Prediction 9/9/2025 Today’s MLB Picks

The Pittsburgh Pirates and Baltimore Orioles meet on Tuesday in MLB action from Oriole Park at Camden Yards. Here’s a Pittsburgh Pirates vs Baltimore Orioles prediction. We will look at this from a betting perspective and determine the best Pirates vs Orioles pick. We will examine:

The Pittsburgh Pirates’ recent form and player performance

The Baltimore Orioles’ recent form and player performance

Recent betting trends and streaks involving the Pirates 

Recent betting trends and streaks involving the Orioles

Recent betting trends in games played between Pittsburgh and Baltimore

A summary that ties it all together and produces a favorable betting outcome for the Pirates and Orioles game.

Pirates are Ice Cold

The Pirates are ice cold heading into this game, and they have lost three games in a row against the Milwaukee Brewers. On Sunday, the offense scored two runs, but even worse was the pitching that gave up ten runs. Bubba Chandler was on the mound and he went 2.2 innings giving up nine hits and nine runs. He had three strikeouts and three walks. Cam Devanney was the only player for the Pirates who was a bright spot and he drove in one run. 

The Pirates are averaging 3.62 runs while their pitching is giving up 4.1 runs per game. The offense is ranked 30th while the pitching is ranked 8th. Overall the pitching has been good, they just haven’t given enough run support with the offense. Mike Burrows is getting the start for the Pirates, and he sits with a 2-4 record and an ERA of 4.08. In his last game against the Dodgers, he went three innings, giving up two hits and zero runs. 

Why the Pirates Will Beat the Orioles

• The Orioles have lost each of their last nine night games against NL Central opponents that held a losing record.
• The Pirates have won each of their last four games against AL East opponents following a loss.
• The Orioles have failed to cover the run line each of their last 12 Tuesday night games against National League opponents that held a losing record.
• The Pirates have covered the run line in 13 of their last 15 road games against American League opponents that held a losing record.
• The Pirates have won the first inning in three of their last four games against opponents that held a losing record.
• The Pirates have led after 3 innings in four of their last five night games against opponents that held a losing record.
• The Pirates have led after 5 innings in three of their last four games at Oriole Park at Camden Yards.

How Do the Orioles Bounce Back?

The Orioles won two of the three games against the Dodgers over the weekend, but they were defeated on Sunday. The Orioles scored two runs. But the pitching gave up five. Even though they won two of the three games, the bats were actually cold most of the weekend. On Sunday, Tomoyuki Sugano got the start and he went three innings giving up seven hits and three runs. Third basemen Emmanuel Rivera was the top offensive player finishing with two hits and one RBI. 

The Orioles are averaging 4.34 runs while their pitching is giving up 4.91 runs per game. The offense is ranked 16th, while the pitching is ranked 25th. Kyle Bradish is going to get the start for the Orioles in this game and he sits with an 0-1 record and an ERA of 3.60. Against the San Diego Padres in his last start he went four innings giving up four hits and two runs. 

Why the Orioles Will Beat the Pirates

• The Pirates have lost nine of their last 10 night games against American League opponents that held a losing record.
• The Orioles have won five of their last six games against National League opponents.
• The Pirates have failed to cover the run line in each of their last five night games against the Orioles following a loss.
• The Orioles have covered the run line in five of their last six games against National League opponents.
• The Pirates have trailed after 3 innings in three of their last four night games against AL East opponents that held a losing record.
• The Orioles have led after 5 innings in four of their last five games at Oriole Park at Camden Yards against opponents that held a losing record.

Pittsburgh Pirates vs Baltimore Orioles Prediction 

The Orioles offense struggled over the weekend and those struggles are going to continue here. Even though Burrows doesn’t go deep, he has been good, and he’s going to have another strong start here. For the Orioles they send Bradish to the mound and he will lockdown a Pirates offense that has had issues all season. This feels like a 4-1 or 4-2 type of game, either way, and that will give some wiggle room with the under. Back the under to cash here.