Philadelphia Phillies vs Los Angeles Dodgers Prediction 9/17/2025 Today’s MLB Picks

The Philadelphia Phillies and the Los Angeles Dodgers meet Wednesday in MLB action from Dodger Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Philadelphia Phillies vs. Los Angeles Dodgers prediction.

Starting Pitching Matchup

The Philadelphia Phillies will send out Jesus Luzardo for the start here and Luzardo is 14-6 with a 4.03 ERA and 200 strikeouts this season. In his career, Luzardo is 1-0 with a 1.82 ERA and 27 strikeouts against the Dodgers. The Los Angeles Dodgers will trot out Blake Snell for the start here and Snell is 4-4 with a 2.79 ERA and 55 strikeouts this season. In his last five starts against the Phillies, Snell is 0-3 with a 5.01 ERA and 32 strikeouts.

Philadelphia Phillies Recap

The Philadelphia Phillies come into this game looking to add on to their 9-6 win over the Dodgers from Tuesday’s matchup to sit at 91-61 this season. After this series, the Phillies will head on the road for another NL West series, taking on the Arizona Diamondbacks this weekend.

Phillies Win 8 Of Their Last 9

Nick Castellanos has 131 hits with 27 doubles including 16 home runs and 66 RBIs while Kyle Schwarber has 136 hits with a team-high 52 home runs and 127 RBIs but also has a team-high 176 strikeouts as well on the year. Bryce Harper has 11 stolen bases, 31 doubles, 26 home runs and 72 RBIs. Trea Turner also has 179 hits with 7 triples, 15 home runs, 69 RBIs and a team-high 36 stolen bases. Max Kepler has 18 doubles and Bryson Stott has 20 doubles, 3 triples, 12 homers and 64 RBIs while Stott also has 23 stolen bases as well this season.

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to bounce back from their loss at the hands of the Phillies on Tuesday to sit at 84-67 this season. After this series, the Dodgers will duke it out with the San Francisco Giants in their series rematch from this past weekend.

Dodgers Drop Back-To-Back Games

Shohei Ohtani has 152 hits including 21 doubles, 49 home runs, 93 RBIs and 8 triples. Michael Conforto has 78 hits with 20 doubles while Teoscar Hernandez has 118 hits with 24 home runs, 27 doubles and 84 RBIs as well this season. Ohtani has a team-high 18 stolen bases while Max Muncy has 10 doubles but also has 73 strikeouts so far this season. Mookie Betts has also chipped in 18 home runs and 75 RBIs as well on the year. Freddie Freeman has also logged 152 hits with a team-high 39 doubles, 20 home runs and 82 RBIs. Andy Pages also has 145 hits with 23 doubles, 24 home runs and 80 RBIs as well this season.

Philadelphia Phillies @ Los Angeles Dodgers Betting Trends: September 16, 2025

• Probable Starting Pitcher: Shohei Ohtani      Record this season: 1-1      ERA: 3.75
• Home Record: 1-0
• Last 5 against Phillies: –

Why the Los Angeles Dodgers will win

• The Dodgers have won each of their last seven home games following an extra innings loss.
• The Phillies have lost four of their last five games following an extra innings win.
• The Phillies have failed to cover the run line in each of their last four games against National League opponents after going to extra innings.
• The Dodgers have covered the run line in six of their last seven games after playing the previous day.
• The Phillies have trailed after 3 innings in eight of their last 10 games as road underdogs.
• The Phillies have lost the first inning in three of their last four night games.
• The Dodgers have led after 5 innings in each of their last 11 home games against opponents that held a winning record.

• Probable Starting Pitcher: Cristopher Sanchez      Record this season: 13-5      ERA: 2.57
• Road Record: 7-5
• Last 5 against Dodgers: 2-0

Why the Philadelphia Phillies will win

• The Phillies have won each of their last eight night games after playing the previous day.
• The Dodgers have lost each of their last four games as favorites after going to extra innings.
• The Dodgers have failed to cover the run line in each of their last eight night games against NL East opponents.
• The Phillies have covered the run line each of their last seven games against teams that held a winning record.
• The Dodgers have trailed after 3 innings in three of their last four night games against opponents that held a winning record.
• The Dodgers have lost the first inning in four of their last five night games against NL East opponents that held a winning record.
• The Dodgers have trailed after 5 innings in six of their last seven games against NL East opponents that held a winning record.

Total Runs Facts

• Each of the Phillies’ last seven games have gone OVER the total runs line.
• Each of the Dodgers’ last six games following an extra innings loss have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Phillies’ last seven games.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the last five games between the Phillies and Dodgers.

Los Angeles Dodgers Player Prop Facts

• Shohei Ohtani has recorded six or more strikeouts in four of his last five appearances against NL East opponents.
• Esteury Ruiz has recorded a Double in four of his last five appearances against NL East opponents that held a winning record.
• Mookie Betts has hit a home run in each of the Dodgers’ last three home games.
• Mookie Betts has recorded at least one hit in each of his last 14 appearances against the Phillies after playing the previous day.
• Shohei Ohtani ranks 2nd amongst qualified players for Slugging Percentage (.608) this season.

Philadelphia Phillies Player Prop Facts

• Kyle Schwarber has hit a home run in each of the Phillies’ last three games.
• Trea Turner has recorded at least one hit in each of his last 15 road appearances.
• Kyle Schwarber ranks 2nd in the league in Home Runs (53) this season.

Matchup/League Facts

• The Dodgers rank 2nd in the league for runs scored this season (767).
• The Dodgers rank 2nd in the league for home runs this season (220).
• The Phillies rank 2nd in the league for hits this season (1339).
• The Phillies rank 2nd in the league for batting average this season (.261).

Philadelphia Phillies vs. Los Angeles Dodgers Prediction

I’m on the over in this one. I had the over on Tuesday because I felt that the total was set too low because of the name brand of the starting pitchers on the marquee and I think it’s more of the same here. Both teams have been solid offensively against lefties as of late, and Luzardo’s been hittable while Snell has had issues in his career against the Phillies. All in all, I think we have some runs coming in this game. Give me the over.