Philadelphia Phillies vs Colorado Rockies Prediction 5/21/25 MLB Picks

The Philadelphia Phillies are visiting the Colorado Rockies on Wednesday, May 21st at the Coors Field in the third game of this series, with the Phillies having a 2-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Philadelphia Phillies vs Colorado Rockies Prediction. We will examine:

The Colorado Rockies’ recent form and player performance

The Philadelphia Phillies’ recent form and player performance

Recent betting trends and streaks involving the Colorado Rockies

Recent betting trends and streaks involving the Philadelphia Phillies

Recent betting trends in games played between the Philadelphia Phillies vs Colorado Rockies

A summary that ties it all together and produces a favorable betting outcome for the Philadelphia Phillies vs Colorado Rockies game

Colorado Rockies Preview

The Colorado Rockies have an 8-40 record this season and are sitting in last place in the NL West. The Rockies have a 5-18 home record and are 20-27 in over/under. They are coming off a 4-7 home defeat by the Phillies, and are 1-7 in their last 8 games. Over is 7-1 in their last 8 home games, and they are playing the Cubs and the Yankees next.

The Rockies have a .217 batting average this season, a .284 OBP, and a .360 Slugging percentage. Colorado’s pitching staff has a 5.88 ERA and 1.62 WHIP.  Hunter Goodman leads the Rockies with 49 hits, adding a team-high 29 RBI, and he is the team’s best hitter with a .285 batting average. Jordan Beck adds a team-high 8 home runs.

Carson Palmquist (L) will take the mound for the Rockies, and he has a 0-1 record, 11.25 ERA, and 1.75 WHIP. He has been torched in his first start of the season, as he gave up 5 runs in 4 innings of work in a 0-8 loss to the Diamondbacks. This will be his first career start against the Phillies.

Philadelphia Phillies Preview

The Philadelphia Phillies have a 30-18 record this season and are sitting in first place in the NL East. They have a 13-10 road record and are 21-26 in over/under. They are coming off a 7-4 road victory over the Rockies, and are 8-2 in their last 10 games. Under is 3-1 in their last 4 games, and they are playing the Athletics and the Braves next.

The Phillies have a .264 batting average this season, a .339 OBP, and a .411 Slugging percentage. Philly’s pitching staff has a 3.76 ERA and 1.23 WHIP.  Trea Turner leads the Phillies with 58 hits and in batting average with .305, while Kyle Schwarber leads the team with 37 RBI and a team-high 17 home runs.

Taijuan Walker (R) will take the mound for the Phillies, and he has a 1-3 record, 2.62 ERA, and 1.25 WHIP. He has been better on the road, with a 1.69 ERA in three road games, and he has given up one run or less in five of his eight appearances this season. In his previous start against the Rockies this season, he had a shutout performance in 6 innings of work. Taijuan Walker has a record of 4-1 with an ERA of 2.09 and 51 strikeouts in 9 appearances against the Rockies in his career.

Why the Colorado Rockies will win

• The Rockies have won five of their last seven games as underdogs against the Phillies following a home loss.
• The Phillies have lost six of their last nine games as road favorites against National League opponents following a win.
• The Rockies have covered the run line in 10 of their last 12 games against the Phillies following a home loss.
• The Phillies have failed to cover the run line in four of their last five games as favorites against National League opponents following a road win.
• The Phillies have trailed after 3 innings in four of their last five road games against NL West opponents.
• The Phillies have trailed after 5 innings in six of their last seven road games against NL West opponents.

Why the Philadelphia Phillies will win

• The Phillies have won each of their last eight games against teams that held a losing record.
• The Rockies have lost each of their last 11 Wednesday games against teams that held a winning record.
• The Rockies have failed to cover the run line in each of their last seven night games at Coors Field following a loss.
• The Phillies have covered the run line each of their last six games against NL West opponents that held a losing record.
• The Rockies have trailed after 3 innings in six of their last seven night games against opponents that held a winning record.
• The Phillies have led after 5 innings in 10 of their last 11 games against National League opponents that held a losing record.
• The Rockies have lost the first inning in three of their last four night games at Coors Field.

Total Runs Facts

• Nine of the Rockies’ last 10 night games against NL East opponents have gone UNDER the total runs line.
• Five of the Phillies’ last six games as favorites against the Rockies have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the Rockies’ last nine night games at Coors Field.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Phillies’ last five road games against NL West opponents.

Matchup/League Facts

• The Rockies rank T1st in the league for triples this season (13).
• The Rockies rank 30th in the league for strikeouts against this season (473).
• The Phillies rank 1st in the league for strikeouts this season (470).
• The Phillies rank 3rd in the league for batting average this season (.264).

Philadelphia Phillies vs Colorado Rockies Prediction

The Phillies are 9-2 in their last 11 overall meetings against the Rockies, but both teams are tied 3-3 in their last 6 meetings in Colorado. Under is 5-1 in their last 6 meetings.

In this Philadelphia Phillies vs Colorado Rockies Prediction, the Phillies are coming as huge -240 road favorites. The Phillies are rightfully favored, as they have been the superior team this season, and the Rockies have the worst record in the MLB. Palmquist looked atrocious in his first start of the season, and facing the red-hot Phillies bats will do him no good.

Taijuan Walker looks great this season, after a terrible 2024 campaign where he had a 7.10 ERA and 1.72 WHIP. He has also been amazing against Rockies bats, so I expect once again the Phillies to have a big lead in the first half. Take the Philadelphia Phillies on the runline in the first 5 innings.