Aug 12, 2025; Cincinnati, Ohio, USA; Cincinnati Reds shortstop Elly De La Cruz (44) high fives second baseman Matt McLain (9) and first baseman Spencer Steer (7) after the victory over the Philadelphia Phillies at Great American Ball Park. Mandatory Credit: Katie Stratman-Imagn Images

Philadelphia Phillies vs Cincinnati Reds Prediction 8/13/2025 Today’s MLB Picks

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Philadelphia (69-50) vs Cincinnati (63-58)

August 13, 2025 at 05:10 PM EDT

The Line: Betting Odds: Cincinnati +1.5 — Over/Under: +8.5

(Get latest betting odds)

The Philadelphia Phillies and Cincinnati Reds meet Wednesday in MLB action at Great American Ball Park. Here’s a Philadelphia Phillies vs Cincinnati Reds Prediction. This article will include a Philadelphia Phillies vs Cincinnati Reds Pick.

Philadelphia Phillies Betting Preview

The Philadelphia Phillies are 69-50 on the year and play the Nationals, Mariners, and Nationals next. The Philadelphia Phillies are batting .254 on the season, have a .325 OBP, and a .417 slugging percentage. The Philadelphia Phillies pitching staff has a 3.70 ERA and a 1.23 WHIP. Trea Turner leads the Philadelphia Phillies with 136 hits and 52 RBI, while Nick Castellanos and Kyle Schwarber have combined for 225 hits and 157 RBI. 

Cristopher Sanchez gets the ball for the Philadelphia Phillies, and he is 11-3 with a 2.36 ERA and 151 strikeouts this season. Sanchez is 1-1 with a 3.86 ERA and 18 strikeouts in his career against the Cincinnati Reds.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 63-58 on the year and play the Brewers, Angels, and Diamondbacks next. The Cincinnati Reds are batting .247 on the season, have a .318 OBP, and a .391 slugging percentage. The Cincinnati Reds pitching staff has a 3.86 ERA and a 1.24 WHIP. Elly De La Cruz leads the Cincinnati Reds with 128 hits and 74 RBI while TJ Friedl and Spencer Steer have combined for 212 hits and 96 RBI.

Hunter Greene gets the ball for the Cincinnati Reds, and he is 4-3 with a 2.72 ERA and 73 strikeouts this season. Greene is 0-1 with a 4.63 ERA and 11 strikeouts in his career against the Philadelphia Phillies.

Why the Cincinnati Reds will win

  • The underdogs have won four of the Reds’ last five games at Great American Ball Park.
  • The Phillies have lost each of their last three games as road favorites against NL Central opponents.
  • The underdogs have covered the run line in seven of the Reds’ last eight games at Great American Ball Park.
  • The Phillies have failed to cover the run line in each of their last four games as road favorites against National League opponents.
  • The Reds have led after 5 innings in four of their last five night games at Great American Ball Park against National League opponents.
  • The Reds have led after 3 innings in four of their last five games.

Why the Philadelphia Phillies will win

  • The Phillies have won eight of their last nine games following a loss.
  • The Reds have lost seven of their last eight games against the Phillies at Great American Ball Park following a win.
  • The Phillies have covered the run line in each of their last five night games against National League opponents following a loss.
  • The Reds have failed to cover the run line in each of their last four games as home underdogs against the Phillies following a win.

Cincinnati Reds Player Prop Facts

  • Miguel Andujar has hit a home run in each of the Reds’ last two games as underdogs against NL opponents.
  • Hunter Greene has recorded seven or more strikeouts in five of his last six appearances at Great American Ball Park.
  • TJ Friedl has recorded at least one hit in each of his last nine appearances against opponents that held a winning record.

Philadelphia Phillies Player Prop Facts

  • Bryce Harper has hit a home run in each of the Phillies’ last two games as road favorites against the Reds.
  • Alec Bohm has recorded at least one Double in each of his last five road appearances against the Reds.
  • Alec Bohm has recorded at least one hit in each of his last 13 road appearances against the Reds.
  • Kyle Schwarber ranks 3rd in the league in Home Runs (42) this season.

Philadelphia Phillies vs Cincinnati Reds Prediction

The Phillies don’t lose back-to-back games often, and Sanchez has been one of the best pitchers in baseball. In his last 51 innings, Sanchez has allowed 40 hits and nine runs. Just elite stuff, folks. Greene is having his best season yet, but he hasn’t pitched since June due to a groin injury. Who knows what to expect from Greene after such a long layoff. The Phillies should have the edge with Sanchez on the bump. Give me the Phillies.

Randy Chambers's Pick: Philadelphia Phillies

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