Orioles vs Astros Prediction 8/16/2025 Today’s MLB Picks

In this article we will formulate an Orioles vs Astros prediction for this MLB game on Saturday, August 16th at Daikin Park in Houston, Texas. Let’s take a look at the prediction for this MLB matchup. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 56-66 this year after they won game one by a score of 7-0 on Friday night. Baltimore jumped out to a 1-0 lead in the fourth inning and they piled on in the later innings for the easy win. The Orioles recorded 13 hits and they committed one error in the game, while they were led by Henderson and Carlson, who both had two RBIs in the win. Baltimore started Young, who allowed one hit and zero earned runs over 8.0 innings, while Hiraldo finished the game. 

Prior to this series, the Orioles won two out of three against the Mariners, but did lose two out of three against the Athletics before that. Baltimore has won three games in a row and they are currently last in the AL East standings. The Baltimore pitching staff has a 4.75 ERA with a 1.39 WHIP and a .263 opponent batting average, while their offense has scored 521 runs with a .240 batting average and a .304 on base percentage this season. Jackson Holliday has led Baltimore with 14 home runs and 45 RBIs, while Gunnar Henderson has added 14 home runs and 53 RBIs this year. The projected starting pitcher for Baltimore is Cade Povich, who is 2-6 with a 4.95 ERA and a 1.43 WHIP over 76.1 innings pitched this year. 

Houston Astros Betting Preview

The Houston Astros are 68-54 this season after they were shutout in game one of this series on Friday night. Houston never got anything going at the plate and they were lucky they weren’t no hit in the blowout loss. The Astros recorded just one hit and they committed one error in the game, while they were led by Urias, who had the only hit. Houston started Valdez, who allowed nine hits and three earned runs over 6.2 innings for the loss, while Dubin allowed three earned runs in relief. 

Prior to this series, the Astros won two out of three against the Red Sox and two out of three against the Yankees. Houston has won six of their last ten games and they are currently first in the AL West standings. The Houston pitching staff has a 3.78 ERA with a 1.21 WHIP and a .232 opponent batting average, while their offense has scored 525 runs with a .256 batting average and a .321 on base percentage this season. Jose Altuve has led Houston with 21 home runs and 63 RBIs, while Yanier Diaz has added 17 home runs and 53 RBIs this year. The projected starting pitcher for Houston is Jason Alexander, who is 3-1 with a 5.02 ERA and a 1.46 WHIP over 37.2 innings pitched this season. 

Why the Astros will beat the Orioles

• The Astros have won each of their last five games against AL East opponents following a home loss.
• The Orioles have lost four of their last five games at Daikin Park.
• The Orioles have failed to cover the run line in seven of their last eight games against American League opponents following a road win.
• The Astros have covered the run line in each of their last four games against the Orioles following a loss.
• The Orioles have trailed after 5 innings in three of their last four games as road underdogs against AL West opponents.

Total Runs Facts

• Eight of the Orioles’ last nine games have gone UNDER the total runs line.
• Five of the Astros’ last six games as favorites against AL East opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Orioles’ last eight games as road underdogs against AL West opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last four night games between the Orioles and Astros.

Houston Astros Player Prop Facts

• Jake Meyers has recorded at least one hit in each of his last 10 appearances against AL opponents.
• Yainer Diaz has hit a home run in three of his last four home appearances after playing the previous day.
• Jeremy Pena has recorded at least one Double in each of his last three appearances against the Orioles at Daikin Park.

Baltimore Orioles Player Prop Facts

• Gunnar Henderson has recorded at least one hit in each of the Orioles’ last 10 games against AL opponents.
• Gunnar Henderson has recorded a Double in four of the Orioles’ last five games against AL opponents.
• Gary Sanchez has hit a home run in five of his last nine appearances against AL West opponents.

Orioles vs Astros Prediction 

Baltimore comes into this matchup with a little momentum, as they have won three games in a row and have scored 16 runs in those three wins. The Orioles are 26-36 on the road this year, while the Astros are 37-26 at home. Houston has allowed at least six runs in three of their last four games, but they are starting Alexander, who has allowed two earned runs in his last 16.2 innings. The O’s are going with Povich, who is not a reliable pitcher in my opinion. Take Houston to break out offensively and get the win here.