New York Yankees vs Seattle Mariners Prediction 4/1/2026 Today’s MLB Picks

The New York Yankees and the Seattle Mariners meet Wednesday in MLB action from T-Mobile Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a New York Yankees vs. Seattle Mariners prediction.

Starting Pitching Matchup

The New York Yankees will send out Cam Schlittler for the start here and Schlittler is 1-0 with a 0.00 ERA and 8 strikeouts this season. The Seattle Mariners will trot out George Kirby here and Kirby is 1-0 with a 1.50 ERA and 6 strikeouts this season.

New York Yankees Recap

The New York Yankees come into this game looking to add on to their 5-0 win over the Mariners from Tuesday’s matchup to sit at 4-1 this season. After this series, the Yankees will head home for a series against the Miami Marlins.

Yankees Looking For Another Series Win

Giancarlo Stanton leads the Yankees with 10 hits including a home run and 4 RBIs while Jose Caballero has 4 hits with an RBI as well. Cody Bellinger has 6 hits and Jazz Chisholm Jr. has 3 hits while Aaron Judge has 2 home runs and 3 RBIs. Ben Rice has 5 hits with a pair of doubles and 3 RBIs while Trent Grisha has 4 hits with a double and a triple. 

Seattle Mariners Recap

The Seattle Mariners come into this game looking to shake off their loss at the hands of the Yankees on Tuesday to drop to 3-3 this season. After this series, the Mariners will head on the road for a game against the Los Angeles Angels.

Mariners Have Two-Game Win Streak Snapped

Brendan Donovan has a team-high 9 hits with 2 home runs and 4 RBIs while Luke Raley has 4 hits with a team-high 3 homers and 6 RBIs this season. Cal Raleigh’s added 3 hits with a double and 2 RBIs but also has a team-high 13 strikeouts. Cole Young’s chipped in a home run and 4 RBIs along with a pair of doubles as his 7 hits as well while Randy Arozarena has 2 doubles and Leo Rivas has a triple this season. Dominic Canzone also has a pair of home runs on the year so far.

New York Yankees @ Seattle Mariners Betting Trends: April 1, 2026

• Probable Starting Pitcher: George Kirby      Record this season: 1-0      ERA: 1.50
• Home Record: 1-0
• Last 5 against Yankees: 0-1

Why the Seattle Mariners will win

• The Mariners have won seven of their last eight day games against American League opponents following a loss.
• The Yankees have lost each of their last four games against AL West opponents following a win.
• The Yankees have failed to cover the run line in each of their last eight Wednesday road games against AL West opponents.
• The Mariners have covered the run line in seven of their last eight day games against American League opponents following a loss.
• The Mariners have led after 3 innings in four of their last five day games against American League opponents.
• The Mariners have won the first inning in three of their last four games as home favorites against AL East opponents.
• The Mariners have led after 5 innings in six of their last seven day games at T-Mobile Park against American League opponents.

• Probable Starting Pitcher: Cam Schlittler      Record this season: 1-0      ERA: 0.00
• Road Record: 1-0
• Last 5 against Mariners: 1-0

Why the New York Yankees will win

• The Mariners have lost each of their last seven games as favorites against AL East opponents.
• The Yankees have won each of their last nine Wednesday day games.
• The Yankees have covered the run line in each of their last 16 games as underdogs against the Mariners.
• The Mariners have failed to cover the run line in each of their last 10 games as favorites against the Yankees following a loss.
• The Mariners have trailed after 5 innings in five of their last six games as favorites against AL East opponents.
• The Mariners have trailed after 3 innings in each of their last five games as favorites against AL East opponents.

Total Runs Facts

• Eight of the Yankees’ last nine day games after playing the previous day have gone UNDER the total runs line.
• Seven of the Mariners’ last eight games as favorites have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the Yankees’ last nine games as road underdogs.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Mariners’ last nine day games.

Seattle Mariners Player Prop Facts

• Cal Raleigh has recorded at least one hit in each of the Mariners’ last seven day games.
• George Kirby has recorded a win in six of his last seven appearances in day games.
• Cal Raleigh has hit a home run in five of the Mariners’ last six games as home favorites against AL East opponents.
• George Kirby ranks T3rd in the league for Wins (1) this season.

New York Yankees Player Prop Facts

• Giancarlo Stanton has recorded two hits in each of the Yankees’ last six road games.
• Amed Rosario has hit a home run in each of his last two appearances with his team as a road underdog.
• Cam Schlittler ranks T1st amongst qualified players for Earned Run Average (0.00) this season.

Matchup/League Facts

• The Mariners rank T2nd in the league for home runs this season (8).
• The Mariners rank 2nd in the league for strikeouts this season (67).
• The Yankees rank 1st in the league for ERA this season (0.61).
• The Yankees rank 1st in the league for opponent batting average this season (.167).

New York Yankees vs. Seattle Mariners Prediction

I’m on the Yankees here. I just think the Yankees are playing the more consistent baseball through the first week of the season and I think Schlittler has the edge here as the Yankees have had a lot of success historically against George Kirby. I think New York takes care of business here so give me the Yankees.

Chris Ruffolo's Pick: New York -105