Nationals vs Cubs Prediction 9/6/2025 Today’s MLB Picks

In this article we will formulate a Nationals vs Cubs prediction for this MLB game on Saturday, September 6th at Wrigley Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Washington Nationals Betting Preview

The Washington Nationals are 56-84 this year after they lost game one by a score of 11-5 on Friday afternoon. Washington cut the deficit to 8-5 in the sixth inning, but couldn’t get any closer in the defeat. The Nationals recorded six hits in the game and they were led by Garcia Jr, who went 1-3 with one home run and three RBIs in the loss. Washington started Irvin, who allowed five hits and seven earned runs over 3.1 innings for the loss, while Ogasawara allowed two earned runs in relief. 

Prior to this series, the Nationals swept the Marlins in three games, but lost all three against the Rays before that. Washington has won three of their last four games and they are currently last in the NL East standings. The Washington pitching staff has a 5.33 ERA with a 1.43 WHIP and a .267 opponent batting average, while the offense has scored 593 runs with a .243 batting average and a .308 on base percentage this season. James Wood has led Washington with 27 home runs and 86 RBIs, while CJ Abrams has added 17 home runs and 53 RBIs this year. The projected starting pitcher for Washington is Brad Lord, who is 4-8 with a 4.34 ERA and a 1.32 WHIP over 103.2 innings pitched this year. 

Chicago Cubs Betting Preview

The Chicago Cubs are 81-60 this season after they won game one by a score of 11-5 on Friday. Chicago scored eight runs in the first four innings and they were able to get the relatively easy victory. The Cubs recorded 10 hits in the game and they were led by Swanson, who went 1-4 with one home run and three RBIs in the win. Chicago started Assad, who allowed three hits and four earned runs over 5.1 innings for the win, while Thielbar allowed one earned run in relief. 

Prior to this series, the Cubs won two out of three against the Braves and two out of three against the Rockies. Chicago has won five of their last seven games and they are currently second in the NL Central standings. The Chicago pitching staff has a 3.88 ERA with a 1.20 WHIP and a .242 opponent batting average, while their offense has scored 699 runs with a .249 batting average and a .320 on base percentage this season. Seiya Suzuki has led Chicago with 27 home runs and 89 RBIs, while Pete Crow-Armstrong has added 28 home runs and 85 RBIs this year. The projected starting pitcher for Chicago is Matthew Boyd, who is 12-7 with a 2.94 ERA and a 1.07 WHIP over 159.1 innings pitched this season. 

Why the Cubs will beat the Nationals

The Nationals have lost each of their last eight day games against NL Central opponents that held a winning record.
The home team has won each of the Nationals’ last four games.
The Nationals have failed to cover the run line in seven of their last eight day games against NL Central opponents.
The home team has covered the run line in each of the Nationals’ last four games.
The Cubs have won the first inning in three of their last four games as favorites against the Nationals at Wrigley Field.
The Cubs have led after 3 innings in four of their last five day games against the Nationals.
The Cubs have led after 5 innings in five of their last six games against the Nationals at Wrigley Field.

Why the Nationals will beat the Cubs 

The Nationals have won seven of their last eight Saturday day games as road underdogs against NL Central opponents.
The Cubs have lost 10 of their last 13 games as favorites against National League opponents following a win.
The Cubs have failed to cover the run line in each of their last 11 day games following a win.
The Nationals have covered the run line in each of their last eight Saturday road games against NL Central opponents.

Total Runs Facts

Each of the Nationals’ last four road games against NL Central opponents have gone OVER the total runs line.
Each of the Cubs’ last three day games against National League opponents have gone OVER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Nationals’ last four games against NL Central opponents.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Cubs’ last 10 home games against NL East opponents.

Chicago Cubs Player Prop Facts

Ian Happ has hit a home run in each of the Cubs’ last three day games against opponents that held a losing record.
Ian Happ has recorded at least one hit in each of his last 10 appearances against NL opponents.
Matthew Boyd has recorded a win in each of his seven previous appearances with the Cubs as home favorites against NL opponents.
Nico Hoerner has recorded a Double in three of his last four appearances in day games against teams that held a losing record.

Washington Nationals Player Prop Facts

CJ Abrams has recorded at least one hit in each of his last nine road appearances against NL Central opponents that held a winning record.
Luis Garcia has hit a home run in each of the Nationals’ last three games as road underdogs against NL opponents.

Nationals vs Cubs Prediction 

Chicago was able to stay hot with a win on Friday to open this series, as they try to strengthen their hold on a wild card spot. The Cubs are 44-26 at home this year, while the Nationals are 27-42 on the road. Washington has scored at least five runs in three straight games and they will face Boyd, who has allowed 4, 5, and 4 earned runs in his last three outings. Chicago will face Lord, who has allowed 13 earned runs in his last 7.1 innings. Both of these pitchers are struggling and I think we will see plenty of scoring, so take the over here.