Minnesota Twins vs Washington Nationals Prediction 07/26/2025 Picks

The Washington Nationals and the Minnesota Twins meet Saturday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Washington Nationals vs. Minnesota Twins prediction.

Starting Pitching Matchup

The Washington Nationals will send out Mitchell Parker here and Parker is 6-10 with a 5.00 ERA and 70 strikeouts this season. This will be Parker’s second career start against Minnesota. The Minnesota Twins will start Joe Ryan here and Ryan is 10-4 with a 2.63 ERA and 132 strikeouts this season. This will be Ryan’s second career start against the Nationals.

Washington Nationals Recap

The Washington Nationals come into this game looking to bounce back from a 1-0 loss at the hands of the Twins on Friday to sit at 41-62 on the year. After this series, the Nationals will head on the road for a series against the Houston Astros.

Nationals Drop Back-To-Back Games

Keibert Ruiz has 63 hits with 12 doubles and a pair of home runs with 25 RBIs while James Wood has 103 hits with 21 doubles and a team-high 24 home runs along with 70 RBIs and 14 stolen bases while also putting up 127 strikeouts. Nathaniel Lowe has 87 hits with 15 doubles and 62 RBIs along with 15 home runs and 118 strikeouts. CJ Abrams has 13 home runs and 37 RBIs along with 22 doubles and 20 stolen bases while Luis Garcia Jr. has 21 doubles and 9 stolen bases of his own this season. Dylan Crews has also logged 11 stolen bases as well this season.

Why the Washington Nationals will win

• The Nationals have won each of their last five games as underdogs against American League opponents following a road loss.
• The Twins have lost each of their last seven night games against NL East opponents following a win.
• The Twins have failed to cover the run line in each of their last nine games against NL East opponents following a win.
• The Nationals have covered the run line in each of their last seven games against the Twins following a loss.

Washington Nationals Player Prop Facts

• Nathaniel Lowe has recorded at least one hit in each of his last 10 Saturday night appearances.
• Paul DeJong has hit a home run in three of his last four road appearances against AL Central opponents.
• James Wood ranks T10th in the league in Home Runs (24) this season.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to add on to their win over the Nationals from Friday’s matchup to sit at 50-53 this season. After this series, the Twins will take on the Boston Red Sox in a series at home.

Twins Alternate Wins & Losses In 6 Straight

Byron Buxton has 92 hits along with 14 doubles, a team-high 23 home runs and 59 RBIs with 17 stolen bases and 4 triples while Carlos Correa has 86 hits with 19 doubles and Willi Castro has 72 hits with 14 doubles as well. Harrison Bader’s added 12 home runs and 38 RBIs while Buxton’s contributed a team-high 97 strikeouts as well this season. Ty France has also added 84 hits, 18 doubles, 6 home runs and 43 RBIs and Trevor Larnach’s chipped in 83 hits with 15 doubles, 13 home runs and 42 RBIs as well this season.

Why the Minnesota Twins will win

• The Nationals have lost 12 of their last 13 games against teams that held a losing record.
• The Twins have won seven of their last eight night games following a home win.
• The Nationals have failed to cover the run line in 12 of their last 13 games against teams that held a losing record.
• The Twins have covered the run line in seven of their last eight night games following a home win.

Minnesota Twins Player Prop Facts

• Byron Buxton has hit a home run in five of his last 12 appearances at Target Field against NL opponents that held a losing record.
• Byron Buxton has recorded two or more hits in three of his last four home appearances after playing the previous day.
• Joe Ryan has recorded seven or more strikeouts in each of his last six Saturday appearances at Target Field.
• Joe Ryan has recorded a win in five of his last six appearances against opponents that held a losing record.
• Joe Ryan ranks T7th in the league for Wins (10) this season.

Total Runs Facts

• Each of the Twins’ last six games as favorites against NL East opponents have gone UNDER the total runs line.
• Nine of the Nationals’ last 10 games against American League opponents have gone OVER the total runs line.

Washington Nationals vs. Minnesota Twins Prediction

I’m on the Twins in this one. I get the case to be made for either side in this one as the Nationals made it competitive on Friday, but I haven’t been impressed with Mitchell Parker on the road this season as his ERA is massively inflated there, and the Twins have hit lefties well as of late. Offensively, the Nationals seem to strike out a ton and Joe Ryan has been a fantastic strikeout pitcher for the better part of his career. I think the Twins get it done here so give me Minnesota.