Sep 4, 2025; Kansas City, Missouri, USA; Kansas City Royals shortstop Bobby Witt Jr. (7) is doused by center fielder Kyle Isbel (28) and second baseman Tyler Tolbert (2) after defeating the Los Angeles Angels at Kauffman Stadium. Mandatory Credit: Jay Biggerstaff-Imagn Images

Minnesota Twins vs Kansas City Royals Prediction 9/5/2025 Today’s MLB Picks

Pick details

Minnesota (62-78) vs Kansas City (71-69)

September 5, 2025 at 07:40 PM EDT

The Line: Betting Odds: Kansas City -1.5 — Over/Under: +8

(Get latest betting odds)

The Minnesota Twins and Kansas City Royals meet Friday in MLB action at Kauffman Stadium. Here’s a Minnesota Twins vs Kansas City Royals Prediction. This article will include a Minnesota Twins vs Kansas City Royals Pick.

Minnesota Twins Betting Preview

The Minnesota Twins are 62-78 on the year and play the Angels, Diamondbacks, and Yankees next. The Minnesota Twins are batting .239 on the season, have a .312 OBP, and a .398 slugging percentage. The Minnesota Twins pitching staff has a 4.55 ERA and a 1.32 WHIP. Trevor Larnach leads the Minnesota Twins with 115 hits and 56 RBI, while Byron Buxton and Brooks Lee have combined for 213 hits and 129 RBI.

The Minnesota Twins didn’t announce a starting pitcher at the time of this writing.

Kansas City Royals Betting Preview

The Kansas City Royals are 71-69 on the year and play the Guardians, Phillies, and Mariners next. The Kansas City Royals are batting .245 on the season, have a .306 OBP, and a .393 slugging percentage. The Kansas City Royals pitching staff has a 3.66 ERA and a 1.24 WHIP. Bobby Witt Jr. leads the Kansas City Royals with 160 hits and 77 RBI while Maikel Garcia and Vinnie Pasquantino have combined for 287 hits and 160 RBI.

Michael Wacha gets the ball for the Kansas City Royals, and he is 8-11 with a 3.52 ERA and 112 strikeouts this season. Wacha is 5-1 with a 3.48 ERA and 45 strikeouts in his career against the Minnesota Twins.

Minnesota Twins @ Kansas City Royals Betting Trends: September 5, 2025

  • Probable Starting Pitcher: Michael Wacha      Record this season: 8-11      ERA: 3.52
  • Home Record: 4-5
  • Last 5 against Twins: 3-0

Why the Kansas City Royals will win

  • The Royals have won 22 of their last 24 games at Kauffman Stadium against AL Central opponents that held a losing record.
  • The Twins have lost eight of their last nine games against American League opponents.
  • The Twins have failed to cover the run line in each of their last four games.
  • The Royals have covered the run line in four of their last five home games against AL Central opponents that held a losing record.
  • The Royals have led after 3 innings in six of their last seven games as home favorites against American League opponents.
  • The Twins have trailed after 5 innings in four of their last five road games against American League opponents.
  • Probable Starting Pitcher: Pablo Lopez      Record this season: 5-3      ERA: 2.82
  • Road Record: 3-3
  • Last 5 against Royals: 3-0

Why the Minnesota Twins will win

  • The Twins have won four of their last five games as underdogs against AL Central opponents following a loss.
  • The Royals have lost three of their last four games as home favorites.
  • The Royals have failed to cover the run line in each of their last five games against the Twins following a win.
  • The Twins have covered the run line in each of their last four games against the Royals following a loss.
  • The Royals have trailed after 5 innings in six of their last eight games against AL Central opponents.

Total Runs Facts

  • Each of the last seven games between the Twins and Royals at Kauffman Stadium have gone UNDER the total runs line.
  • Eleven of the Twins’ last 12 games as underdogs against the Royals have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in nine of the Twins’ last 10 games as road underdogs against American League opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in 12 of the Royals’ last 15 night games at Kauffman Stadium.

Kansas City Royals Player Prop Facts

  • Vinnie Pasquantino has hit a home run in five of the Royals’ last seven games at Kauffman Stadium against opponents that held a losing record.
  • Bobby Witt Jr. has recorded a Double in four of the Royals’ last five games against the Twins at Kauffman Stadium.
  • Michael Wacha has recorded five or more strikeouts in eight of his last nine appearances in night games against AL Central teams that held a losing record.
  • Maikel Garcia has recorded at least one hit in each of his last nine appearances with the Royals as home favorites against AL Central opponents.
  • Michael Wacha has recorded a win in eight of his last nine appearances in night games against AL Central teams that held a losing record.
  • Bobby Witt Jr. ranks 6th in the league in Steals (34) this season.

Minnesota Twins Player Prop Facts

  • Pablo Lopez has recorded four or more strikeouts in each of his 18 previous road appearances against AL opponents that held a winning record.
  • Trevor Larnach has hit a home run in each of his last two appearances with the Twins as road underdogs against AL Central opponents.
  • Trevor Larnach has recorded at least one hit in each of his last six appearances.

Matchup/League Facts

  • The Royals rank T2nd in the league for runs allowed this season (544).
  • The Royals rank 28th in the league for runs scored this season (537).
  • The Twins rank 26th in the league for hits allowed this season (1238).
  • The Twins rank 25th in the league for hits this season (1124).

Minnesota Twins vs Kansas City Royals Prediction

The Royals aren’t lighting the world on fire, but they have something to play for, just two games out of a wild card spot. Wacha has been solid at home, where he has a 3.01 ERA and .244 allowed batting average. The Twins were just swept by the White Sox in a four-game series. You, myself, and seven of your friends could beat the White Sox at least once if we had four tries. There’s no backing the Twins here at all. Give me the Royals at home.

Randy Chambers's Pick: Kansas City Royals

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