Milwaukee Brewers vs Pittsburgh Pirates Prediction 9/6/2025 Today’s MLB Picks

The Milwaukee Brewers and Pittsburgh Pirates meet Saturday in MLB action at PNC Park. Here’s a Milwaukee Brewers vs Pittsburgh Pirates Prediction. This article will include a Milwaukee Brewers vs Pittsburgh Pirates Pick.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 87-55 on the year and play the Rangers, Cardinals, and Angels next. The Milwaukee Brewers are batting .259 on the season, have a .332 OBP, and a .407 slugging percentage. The Milwaukee Brewers pitching staff has a 3.62 ERA and a 1.24 WHIP. Brice Turang leads the Milwaukee Brewers with 149 hits and 71 RBI, while Sal Frelick and William Contreras have combined for 274 hits and 123 RBI.

Brandon Woodruff gets the ball for the Milwaukee Brewers, and he is 5-2 with a 3.69 ERA and 66 strikeouts this season. Woodruff is 7-3 with a 3.25 ERA and 107 strikeouts in his career against the Pittsburgh Pirates.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 64-78 on the year and play the Orioles, Nationals, and Cubs next. The Pittsburgh Pirates are batting .234 on the season, have a .307 OBP, and a .352 slugging percentage. The Pittsburgh Pirates pitching staff has a 3.87 ERA and a 1.22 WHIP. Bryan Reynolds leads the Pittsburgh Pirates with 127 hits and 70 RBI while Andrew McCutchen and Tommy Pham have combined for 194 hits and 101 RBI.

Mitch Keller gets the ball for the Pittsburgh Pirates, and he is 6-13 with a 4.21 ERA and 132 strikeouts this season. Keller is 1-6 with a 5.59 ERA and 65 strikeouts in his career against the Milwaukee Brewers.

Milwaukee Brewers @ Pittsburgh Pirates Betting Trends: September 6, 2025

• Probable Starting Pitcher: Mitch Keller      Record this season: 6-13      ERA: 4.21
• Home Record: 3-8
• Last 5 against Brewers: 1-2

Why the Pittsburgh Pirates will win

• The Pirates have won seven of their last eight games as home underdogs following a loss.
• The Brewers have lost each of their last seven night games against the Pirates following a road win.
• The Pirates have covered the run line in each of their last six games as underdogs following a loss.
• The Brewers have failed to cover the run line in each of their last six games against National League opponents following a win.
• The Brewers have trailed after 5 innings in four of their last five games against NL Central opponents.
• The Brewers have trailed after 3 innings in four of their last five road games against NL Central opponents.

• Probable Starting Pitcher: Brandon Woodruff      Record this season: 5-2      ERA: 3.69
• Road Record: 3-2
• Last 5 against Pirates: 1-1

Why the Milwaukee Brewers will win

• The Brewers have won each of their last eight road games against National League opponents that held a losing record.
• The Pirates have lost each of their last four night games against NL Central opponents that held a winning record.
• The Brewers have covered the run line each of their last eight road games against National League opponents that held a losing record.
• The Pirates have failed to cover the run line in each of their last five games against the Brewers following a loss.

Total Runs Facts

• Four of the Pirates’ last five night games after playing the previous day have gone UNDER the total runs line.
• Three of the Brewers’ last four games against NL Central opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Brewers’ last six Saturday night games against National League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Pirates’ last six night games against NL Central opponents.

Pittsburgh Pirates Player Prop Facts

• Andrew McCutchen has hit a home run in six of his last 19 appearances with the Pirates as home underdogs against the Brewers.
• Mitch Keller has recorded five or more strikeouts in each of his last seven appearances with the Pirates as underdogs against the Brewers.
• Bryan Reynolds has recorded at least one hit in 10 of his last 11 appearances against the Brewers after playing the previous day.

Milwaukee Brewers Player Prop Facts

• Christian Yelich has hit a home run in each of his last two appearances in night games against NL Central teams that held a losing record.
• Jackson Chourio has recorded at least one Double in three of his last four appearances with the Brewers as road favorites.
• Brandon Woodruff has recorded eight or more strikeouts in three of his last four road appearances against NL opponents that held a losing record.
• Brice Turang has recorded at least one hit in each of his last 18 appearances in night games.
• Brandon Woodruff has recorded a win in each of his last five appearances in night games against teams that held a losing record.

Matchup/League Facts

• The Pirates rank 30th in the league for RBIs this season (499).
• The Pirates rank 30th in the league for slugging percentage this season (.352).
• The Brewers rank 2nd in the league for batting average this season (.259).
• The Brewers rank 2nd in the league for on-base percentage this season (.332).

Milwaukee Brewers vs Pittsburgh Pirates Prediction

The Brewers continue to win games and aren’t a team I’m excited to bet against. Woodruff has been solid this season as well in limited frames, and he’s allowing a .198 batting average in 26.2 road innings. The Pirates aren’t good, and Keller is coming off an August where he allowed 35 hits and 21 earned runs in 29 innings. Keller has also had zero success against the Brewers, which includes allowing a .333 batting average and .386 on base percentage in 117 at bats against current hitters. Give me the Brewers yet again.