Sep 23, 2025; Philadelphia, Pennsylvania, USA; Miami Marlins shortstop Xavier Edwards (9) and second base Otto Lopez (6) celebrate win against the Philadelphia Phillies at Citizens Bank Park. Mandatory Credit: Eric Hartline-Imagn Images

Marlins vs Phillies Prediction 9/24/2025 Today’s MLB Picks

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Miami (77-80) vs Philadelphia (92-65)

September 24, 2025 at 06:45 PM EDT

The Line: Betting Odds: Philadelphia -190 — Over/Under: +8.5

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In this article we will formulate a Marlins vs Phillies prediction for this MLB game on Wednesday, September 24th at Citizens Bank Park in Philadelphia, Pennsylvania. Let’s take a look at the prediction for this MLB matchup. 

Miami Marlins Betting Preview

The Miami Marlins are 77-80 this year after they won game one by a score of 6-5 on Tuesday night. Miami trailed 3-0 early in the game, but tied it in the ninth and ended up winning in the 11th inning. The Marlins recorded 10 hits and they committed one error in the game, while they were led by Hicks, Marsee, Hernandez, Edwards, and Conine, who all had one RBI in the win. Miami started Cabrera, who allowed five hits and three earned runs over 4.0 innings, while Simpson picked up the win in relief. 

Prior to this series, the Marlins won all three against the Rangers and all three against the Rockies. Miami has won 11 of their last 12 games and they are third in the NL East standings. The Miami pitching staff has a 4.62 ERA with a 1.30 WHIP and a .249 opponent batting average, while the offense has scored 698 runs with a .252 batting average and a .315 on base percentage this season. Kyle Stowers (IL) has led Miami with 25 home runs and 73 RBIs, while Agustin Ramirez has added 21 home runs and 67 RBIs this year. The projected starting pitcher for Miami is Ryan Weathers, who is 2-1 with a 3.21 ERA and a 1.22 WHIP over 33.2 innings pitched this year. 

Philadelphia Phillies Betting Preview

The Philadelphia Phillies are 92-65 this season after they lost game one in extra innings on Tuesday. Philadelphia blew a 3-0 lead in the eighth inning and couldn’t score in the 11th for the loss. The Phillies recorded nine hits and they committed two errors in the game, while they were led by Kemp, who went 1-4 with one home run and two RBIs in the loss. Philadelphia started Sanchez, who allowed three hits and zero earned runs over 7.0 innings, while Duran blew the save and Trivino got the loss. 

Prior to this series, the Phillies lost two out of three against the Diamondbacks, but did win two out of three against the Dodgers before that. Philadelphia has lost four of their last five games and they are first in the NL East standings. The Philadelphia pitching staff has a 3.87 ERA with a 1.25 WHIP and a .246 opponent batting average, while the offense has scored 761 runs with a .260 batting average and a .330 on base percentage this season. Kyle Schwarber has led Philadelphia with 54 home runs and 130 RBIs, while Nick Castellanos has added 17 home runs and 71 RBIs this year. The projected starting pitcher for Philadelphia is Jesus Luzardo, who is 14-7 with a 4.08 ERA and a 1.25 WHIP over 176.2 innings pitched this season. 

Why the Phillies will beat the Marlins 

The Phillies have won each of their last 11 games against the Marlins after going to extra innings.
The Marlins have lost eight of their last nine night games against NL East opponents following a road win.
The Phillies have covered the run line in 12 of their last 13 games following a home loss.
The Marlins have failed to cover the run line in 12 of their last 14 night games against the Phillies following a win.
The Phillies have won the first inning in three of their last four games against the Marlins.
The Phillies have led after 3 innings in four of their last five games against opponents that held a losing record.
The Marlins have trailed after 5 innings in 15 of their last 17 games at Citizens Bank Park against opponents that held a winning record.

Why the Marlins will beat the Phillies


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The Marlins have won seven of their last eight games as underdogs.
The Phillies have lost three of their last four games as favorites after going to extra innings.
The Marlins have covered the run line in each of their last seven games as road underdogs following an extra innings win.
The Phillies have failed to cover the run line each of their last five games at Citizens Bank Park against teams that held a losing record.

Total Runs Facts

Each of the Phillies’ last seven home games have gone OVER the total runs line.
Seven of the Marlins’ last eight night games against National League opponents have gone OVER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Phillies’ last nine games as favorites against National League opponents.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Marlins’ last four games as underdogs against NL East opponents.

Marlins vs Phillies Prediction 

Miami extended their lengthy winning streak in extra innings on Tuesday night in game one of this series and they are one of the hottest teams in the league right now. The Marlins are 41-38 on the road this season, while the Phillies are 51-25 at home. Philadelphia has allowed 19 runs in their last three games and they are starting Luzardo, who has allowed eight earned runs in his last 15.0 innings of work. Miami is going with Weathers, who has allowed 3+ earned runs in three of his last four outings. Take the over in this contest.

David Racey's Pick: Over 8.5

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