Los Angeles Dodgers vs San Diego Padres Prediction 8/23/2025 Today’s MLB Picks

The Los Angeles Dodgers and San Diego Padres meet Saturday in MLB action at Petco Park. Here’s a Los Angeles Dodgers vs San Diego Padres Prediction. This article will include a Los Angeles Dodgers vs San Diego Padres Pick.

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers are 73-56 on the year and play the Reds, Diamondbacks, and Pirates next. The Los Angeles Dodgers are batting .254 on the season, have a .331 OBP, and a .440 slugging percentage. The Los Angeles Dodgers pitching staff has a 4.15 ERA and a 1.31 WHIP. Shohei Ohtani leads the Los Angeles Dodgers with 138 hits and 83 RBI, while Freddie Freeman and Andy Pages have combined for 259 hits and 143 RBI.

Tyler Glasnow gets the ball for the Los Angeles Dodgers, and he is 1-1 with a 3.12 ERA and 72 strikeouts this season. Glasnow is 0-0 with a 2.79 ERA and 35 strikeouts in his career against the San Diego Padres.

San Diego Padres Betting Preview

The San Diego Padres are 73-56 on the year and play the Mariners, Twins, and Orioles next. The San Diego Padres are batting .252 on the season, have a .322 OBP, and a .385 slugging percentage. The San Diego Padres pitching staff has a 3.52 ERA and a 1.20 WHIP. Manny Machado leads the San Diego Padres with 146 hits and 78 RBI, while Luis Arraez and Fernando Tatis Jr. have combined for 273 hits and 99 RBI.

Nestor Cortes gets the ball for the San Diego Padres, and he is 1-2 with a 5.87 ERA and 22 strikeouts this season. Cortes is 0-1 with a 4.91 ERA and 8 strikeouts in his career against the Los Angeles Dodgers.

Why the San Diego Padres will win

• The Padres have won five of their last six games as home underdogs against National League opponents.
• The Dodgers have lost six of their last eight games as road favorites after playing the previous day.
• The Padres have covered the run line in each of their last 11 games as underdogs following a win.
• The Dodgers have failed to cover the run line in five of their last six road games against teams that held a winning record.
• The Dodgers have trailed after 3 innings in three of their last four games at Petco Park.

Why the Los Angeles Dodgers will win

• The Dodgers have won nine of their last 10 games against NL West opponents following a road loss.
• The Padres have lost four of their last five night games against the Dodgers following a win.
• The Padres have failed to cover the run line in each of their last six Saturday night games at Petco Park.
• The Dodgers have covered the run line in six of their last seven games against the Padres at Petco Park following a loss.
• The Padres have trailed after 3 innings in each of their last four night games against opponents that held a winning record.
• The Padres have trailed after 5 innings in three of their last four games as underdogs against National League opponents.

San Diego Padres Player Prop Facts

• Gavin Sheets has recorded at least one hit in each of his last 11 appearances with his team as an underdog against the Dodgers.
• Luis Campusano has hit at least one home run in three of his last six appearances against the Dodgers at Petco Park.
• Luis Arraez has recorded at least one Double in each of the Padres’ last three games as underdogs against NL West opponents.
• Luis Arraez ranks 5th in the league in Hits (145) this season.

Los Angeles Dodgers Player Prop Facts

• Tyler Glasnow has recorded seven or more strikeouts in each of his last six appearances against NL West opponents that held a winning record.
• Miguel Rojas has recorded at least one hit in each of his last 11 road appearances against NL West opponents.
• Shohei Ohtani has hit at least one home run in four of the Dodgers’ last five Saturday night games against opponents that held a winning record.
• Shohei Ohtani ranks 3rd in the league in Home Runs (44) this season.

Los Angeles Dodgers vs San Diego Padres Prediction

The Padres are on a heater so you can make a case for them in this spot. I just can’t get behind Cortes and his 5.87 ERA and 1.65 WHIP. Cortes isn’t the same pitcher he was for the Yankees a few years ago. Glasnow is finding his footing, allowing 13 hits and five runs in his last 17.2 innings. In 42.2 home innings, Glasnow has a 2.32 ERA and .179 allowed batting average. I’m going to lean toward the Dodgers due to the more trustworthy starting pitcher.