Los Angeles Dodgers vs San Diego Padres Prediction 5/20/2026 Today’s MLB Picks

The Los Angeles Dodgers and San Diego Padres meet Wednesday in MLB action at Petco Park. Here’s a Los Angeles Dodgers vs. San Diego Padres Prediction. This article will include a Los Angeles Dodgers vs. San Diego Padres Pick.

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers are 30-19 on the year and play the Rockies and Brewers next. The Los Angeles Dodgers are batting .261 on the season and have a .342 OBP, and a .429 slugging percentage. The Los Angeles Dodgers’ pitching staff has a 3.19 ERA and a 1.10 WHIP. Andy Pages leads the Los Angeles Dodgers with 53 hits and 42 RBI, while Freddie Freeman and Shohei Ohtani have combined for 93 hits and 48 RBI.

Shohei Ohtani gets the ball for the Los Angeles Dodgers, and he is 3-2 with a 0.82 ERA and 50 strikeouts this season. Ohtani is 0-1 with a 9.00 ERA and 5 strikeouts in his career against the San Diego Padres.

San Diego Padres Betting Preview

The San Diego Padres are 29-19 on the year and play the Phillies and Athletics next. The San Diego Padres are batting. 222 on the season, have a .294 OBP, and have a .370 slugging percentage. The San Diego Padres’ pitching staff has a 3.93 ERA and a 1.24 WHIP. Xander Bogaerts leads the San Diego Padres with 43 hits and 23 RBI, while Miguel Andujar and Fernando Tatis Jr. have combined for 82 hits and 32 RBI.

Randy Vasquez gets the ball for the San Diego Padres, and he is 5-1 with a 2.68 ERA and 45 strikeouts this season. Vasquez is 0-1 with a 4.05 ERA and 10 strikeouts in his career against the Los Angeles Dodgers.

Why the San Diego Padres will win

• The Padres have won six of their last seven games as home underdogs against National League opponents following a loss.
• The Dodgers have lost four of their last five games as road favorites against the Padres following a road win.
• The Dodgers have failed to cover the run line in each of their last seven games at Petco Park following a win.
• The underdogs have covered the run line in nine of the Padres’ last 10 games at Petco Park.
• The Dodgers have trailed after 5 innings in each of their last five games at Petco Park against opponents that held a winning record.
• The Dodgers have trailed after 3 innings in each of their last four games against National League opponents that held a winning record.

Why the Los Angeles Dodgers will win

• The Dodgers have won six of their last seven games after playing the previous day.
• The Padres have lost each of their last four night games at Petco Park following a home loss.
• The Padres have failed to cover the run line in each of their last four night games at Petco Park following a home loss.
• The Dodgers have covered the run line in four of their last five games as favorites following a win.

Total Runs Facts

• Seven of the Padres’ last eight home games after playing the previous day have gone UNDER the total runs line.
• Four of the Dodgers’ last five road games against NL West opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of Shohei Ohtani’s last eight road appearances as a starter.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Padres’ last four home games against NL West opponents.

San Diego Padres Player Prop Facts

• Miguel Andújar has hit a home run in three of his last four appearances with his team as a home underdog against NL opponents.
• Miguel Andújar has recorded at least one hit in each of his last nine appearances with his team as a home underdog against NL opponents.

Los Angeles Dodgers Player Prop Facts

• Freddie Freeman has hit two home runs in two of the Dodgers’ last three road games against the Padres.
• Shohei Ohtani has recorded eight or more strikeouts in five of his last six appearances with the Dodgers as favorites against NL opponents.
• Tommy Edman has recorded at least one hit in each of his last six appearances with the Dodgers as favorites against the Padres.

Matchup/League Facts

• The Padres rank 29th in the league for on-base percentage this season (.294).
• The Padres rank T2nd in the league for home runs allowed this season (39).
• The Dodgers rank 2nd in the league for hits this season (428).
• The Dodgers rank 2nd in the league for ERA this season (3.19).

Los Angeles Dodgers vs San Diego Padres Prediction

I’ll continue to back the Padres as a home dog, as they’re too good of a team to turn down in the plus money price. Yes, Ohtani has been ridiculous this season and the Dodgers are the more stacked team. However, Vasquez has held his own with a 2.68 ERA and 1.11 WHIP on the season. In his last 11 innings, Vasquez has allowed 10 hits and 1 run while allowing zero walks and 9 strikeouts. The Padres are 8-1 this season when Vasquez pitches. I want the more favorable price in this spot.

Randy Chambers's Pick: San Diego Padres