Aug 24, 2025; Pittsburgh, Pennsylvania, USA;  Pittsburgh Pirates starting pitcher Paul Skenes (30) pitches the Colorado Rockies during the second inning at PNC Park. Mandatory Credit: Charles LeClaire-Imagn Images

Los Angeles Dodgers vs Pittsburgh Pirates Prediction 9/4/2025 Today’s MLB Picks

Pick details

Los Angeles (78-61) vs Pittsburgh (63-77)

September 4, 2025 at 06:40 PM EDT

The Line: Betting Odds: Pittsburgh +110 — Over/Under: +7

(Get latest betting odds)

In this article, we will formulate a Dodgers vs Pirates Prediction for this MLB game on Thursday, September 4th at the PNC Park in the third game of this series, with the Pirates having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.

Pittsburgh Pirates Preview

The Pittsburgh Pirates have a 63-77 record this season and are sitting on the last place of the NL Central. They have a 41-30 home record, and are 57-78 in over/under. They are coming off a 3-0 home victory over the Dodgers, and are 6-2 in their last 8 games. Under is 5-2 in their last 7 games are playing the Brewers and the Orioles next.

The Pirates have a .234 batting average this season, .308 OBP and .353 slugging percentage. Pittsburgh’s pitching staff has a 3.88 ERA and 1.22 WHIP. Bryan Reynolds leads the Pirates with 125 hits, and a team-high 69 RBI. Andrew McCutchen the team’s best hitter with a .247 batting average, while Oneil Cruz leads the team in home runs, with 19.

Paul Skenes (R) is the projected starting pitcher for the Pirates, and he has a 9-9 record, 2.05 ERA and 0.95 WHIP.

Los Angeles Dodgers Preview

The Los Angeles Dodgers have a 78-61 record this season and are sitting on the first place of the NL West. The Dodgers have a 33-35 road record and 65-68 in over/under. They are coming off a 0-3 road defeat by the Pirates, and are 1-4 in their last 5 games. Under is 5-3-1 in their last 9 games, and are playing the Orioles and the Rockies next.

The Dodgers have a .252 batting average this season, .329 OBP and .437 slugging percentage. LA’s pitching staff has a 4.12 ERA and 1.29 WHIP.  Sohei Ohtani leads the Dodgers with 148 hits, in RBI, with 87 and in home runs, with 46. Freddie Freeman is the team’s best hitter with a .297 batting average.

Blake Snell (L) is the projected starting pitcher for the Dodgers, and he has a 3-3 record, 2.41 ERA and 1.37 WHIP.

Dodgers vs Pirates Prediction

The Pirates are 3-2 in their last 5 meetings against the Dodgers, and 3-1 in their last 4 meetings in Pittsburgh. The Dodgers are 6-3 in their last 9 meetings and over is 7-3 in their last 10 meetings.

In this Dodgers vs Pirates Prediction, the Dodgers are coming as -125 road favorites. This is the definition of a pitcher’s duel, as Skenes faces off with Snell. Skenes has been elite this season and even better at home, with a 1.65 home ERA, and his only start against the Dodgers this season was a shutout. Snell has also been in great form since returning from an injury and he should keep in check the league’s worst offense, which is even weaker against left-handed pitching. I expect a low-scoring game, so take the under 7 in this one.

Nikos Lagouretos's Pick: Under 7

Hot Cappers

Latest Picks & Game Previews

  • Phillies vs Brewers Prediction 9/4/2025 Today’s MLB Picks

    September 04, 2025

  • Los Angeles Dodgers vs Pittsburgh Pirates Prediction 9/4/2025 Today’s MLB Picks

    September 04, 2025

  • Cleveland Guardians vs Tampa Bay Rays Prediction 9/4/2025 Today’s MLB Picks

    September 04, 2025

  • Yankees vs Astros Prediction 9/4/2025 Today’s MLB Picks

    September 04, 2025

  • Los Angeles Angels vs Kansas City Royals Prediction 9/4/2025 Today’s MLB Picks

    September 04, 2025

  • Chicago White Sox vs Minnesota Twins Prediction 9/4/2025 Today’s MLB Picks

    September 04, 2025

  • Cowboys vs Eagles Prediction 9/4/2025 Today’s NFL Picks

    September 04, 2025

  • Carlos Alcaraz vs Novak Djokovic Prediction 9/5/2025 Today’s Tennis Picks

    September 05, 2025

  • James Madison vs Louisville Prediction 9/5/2025 Today’s College Football Picks

    September 05, 2025

  • Western Illinois vs Northwestern Prediction 9/5/2025 Today’s College Football Picks

    September 05, 2025