Los Angeles Dodgers vs Houston Astros Prediction 5/5/2026 Today’s MLB Picks

The Los Angeles Dodgers and the Houston Astros meet Tuesday in MLB action from Daikin Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Los Angeles Dodgers vs. Houston Astros prediction.

Starting Pitching Matchup

The Los Angeles Dodgers will send out Shohei Ohtani for the start here and Ohtani is 2-1 with a 0.60 ERA and 34 strikeouts this season. In his last five starts against the Astros, Ohtani is 1-3 with a 4.32 ERA and 30 strikeouts. Peter Lambert will start here for the Astros and is 1-2 with a 3.52 ERA and 19 strikeouts. In his last five starts against the Dodgers, Lambert is 0-3 with a 9.74 ERA and 12 strikeouts. 

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to add on to their 8-3 win over Houston from Monday’s opener to sit at 22-13 this season. After this series, the Dodgers will head home for a series against the Atlanta Braves.

Dodgers Win Back-To-Back Games

Going into Monday, Andy Pages has 39 hits with 8 doubles, 5 home runs and 27 RBIs while Teoscar Hernandez has 27 hits with 4 doubles, 4 home runs and 17 RBIs. Shohei Ohtani has 30 hits with 6 doubles, 6 home runs and 13 RBIs and Freddie Freeman has 35 hits with 8 doubles, a triple, 3 home runs and 16 RBIs this season. Will Smith has 3 home runs as well this season. Max Muncy’s added 33 hits with 5 doubles, 9 home runs and 13 RBIs and Kyle Tucker has 30 hits with 7 doubles, 3 home runs and 16 RBIs this season.

Houston Astros Recap

The Houston Astros come into this game looking to shake off their loss at the hands of the Dodgers on Monday to slip to 14-22 this season. After this series, the Astros will head on the road for a series against the Cincinnati Reds.

Astros Have Two-Game Win Streak Snapped

Entering Monday, Yordan Alvarez has 43 hits with 9 doubles, 12 home runs and 27 RBIs while Christian Walker has 40 hits with 9 doubles, 8 home runs and 26 RBIs on the year. Jose Altuve’s chipped in 31 hits with 9 doubles, 3 home runs and 8 RBIs and Carlos Correa has 34 hits with 8 doubles, 3 home runs and 16 RBIs. Cam Smith also has 27 hits with 6 doubles, 4 home runs and 17 RBIs. Yainer Diaz also has 25 hits with 5 doubles, 2 home runs and 14 RBIs.

Los Angeles Dodgers @ Houston Astros Betting Trends: May 5, 2026

• Probable Starting Pitcher: Peter Lambert      Record this season: 1-2      ERA: 3.52
• Home Record: 0-1
• Last 5 against Dodgers: 0-3

Why the Houston Astros will win

• The Astros have won six of their last seven games as underdogs against NL West opponents.
• The Dodgers have lost four of their last five games as favorites following a road win.
• The Dodgers have failed to cover the run line in seven of their last eight games against AL West opponents that held a losing record.
• The Astros have covered the run line in each of their last five games against the Dodgers following a loss.
• The Dodgers have trailed after 5 innings in four of their last five night games.
• The Astros have won the first inning in five of their last six games as home underdogs.
• The Astros have led after 3 innings in five of their last six home games against NL West opponents.

• Probable Starting Pitcher: Shohei Ohtani      Record this season: 2-1      ERA: 0.60
• Road Record: 0-0
• Last 5 against Astros: 1-3

Why the Los Angeles Dodgers will win

• The Astros have lost seven of their last eight home games.
• The Dodgers have won each of their last six night games against American League opponents following a road win.
• The Astros have failed to cover the run line in each of their last seven games against National League opponents following a loss.
• The road team has covered the run line in each of the last six games between the Dodgers and Astros.
• The Astros have trailed after 3 innings in eight of their last nine home games against NL West opponents that held a winning record.
• The Astros have trailed after 5 innings in each of their last six home night games.

Total Runs Facts

• Each of the Astros’ last eight games as home underdogs have gone OVER the total runs line.
• Nine of the Dodgers’ last 10 night games against AL West opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Astros’ last 10 night games at Daikin Park.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of Shohei Ohtani’s last seven appearances as a starter.

Houston Astros Player Prop Facts

• Christian Walker has hit at least one home run in seven of his last nine appearances against the Dodgers.
• Yordan Alvarez has recorded at least one hit in each of the Astros’ last 16 home games.
• Yordan Alvarez ranks 2nd amongst qualified players for Slugging Percentage (.667) this season.

Los Angeles Dodgers Player Prop Facts

• Kyle Tucker has hit at least one home run in each of his last six appearances in night games against AL West teams that held a losing record.
• Kyle Tucker has recorded at least one hit in each of his last 13 road appearances against AL opponents that held a losing record.
• Max Muncy ranks 9th amongst qualified players for Slugging Percentage (.575) this season.

Matchup/League Facts

• The Astros rank 1st in the league for doubles this season (73).
• The Astros rank 30th in the league for ERA this season (5.78).
• The Dodgers rank 1st in the league for on-base percentage this season (.352).
• The Dodgers rank 1st in the league for opponent batting average this season (.213).

Los Angeles Dodgers vs. Houston Astros Prediction

I’m on the Dodgers here. I get the case to be made for the Astros but the thing for me is that I’m still having a hard time buying into Peter Lambert as a solid option for this Astro rotation and this Houston bullpen continues to be far too volatile for my liking. Ohtani’s been outstanding and it looks like the Dodgers’ offense has woken up to where I’m fine backing them at this number here. Give me the Dodgers.

Chris Ruffolo's Pick: LA Dodgers -185