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Los Angeles Dodgers vs Cleveland Guardians Prediction 5/26/25 MLB Picks

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Cleveland Guardians (29-23) vs Los Angeles Dodgers (32-21)

May 26, 2025 at 06:10 PM EDT

The Line: Betting Odds: Cleveland Guardians +145 / Los Angeles Dodgers -175 — Over/Under: 8

(Get latest betting odds)

In this article, we will formulate a Dodgers vs Guardians prediction for this MLB game on Monday, May 26, at Progressive Field in Cleveland, Ohio. Let’s take a look at the prediction for this MLB matchup.

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers (33-21, 13-13 Away) bounced back from getting swept by the Angels with a win over the Diamondbacks, but lost the most recent series to the New York Mets on the road. In last night’s 3-1 defeat, the Dodgers committed even four errors, while Landon Knack took the loss after allowing three runs on four hits with five strikeouts and no walks in 6.0 innings.

This year, the Dodgers average 5.55 runs per game (3rd in the MLB) on a .263/.340/.459 triple-slash. When it comes to pitching, the Dodgers’ staff has a 4.09 ERA (20th) and 1.28 WHIP (17th). Teoscar Hernandez leads the Dodgers with a .307 batting average, ten home runs, and 41 RBI this season.

The projected starting pitcher for the Dodgers is Yoshinobu Yamamoto, who is 5-3 in ten starts this season, with a 1.86 ERA and 0.91 WHIP in 58.0 innings.

Cleveland Guardians Betting Preview

The Cleveland Guardians (29-23, 14-8 Home) were on a four-game winning streak before suffering a 5-0 loss to the Detroit Tigers on the road. The Guardians won the opening three games of that series, but couldn’t sweep the Tigers. Cleveland made three errors opposite Detroit’s zero in the latest defeat, while Logan Allen took the loss after allowing five runs (four earned) on six hits with two strikeouts and four walks in 3.2 innings.

This season, the Guardians average 4.02 runs per game (23rd in the MLB) on a .231/.304/.377 triple-slash. When it comes to pitching, the Guardians’ staff has a 3.97 ERA (16th) and 1.38 WHIP (24th). Kyle Manzardo leads the Guardians with a .216 batting average, ten home runs, and 27 RBI this season.

Gavin Williams will take the mound for the Guardians on Monday. The 25-year-old right-hander has a 4-2 record in ten starts this year with a 3.94 ERA and 1.52 WHIP in 48.0 innings.

Total Runs Facts

  • Each of the Dodgers’ last four road games after playing the previous day have gone UNDER the total runs line.
  • Six of the Guardians’ last seven night games after playing the previous day have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in 12 of the Guardians’ last 13 games as underdogs against National League opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Dodgers’ last five games as favorites against American League opponents.

Matchup/League Facts

  • The Guardians rank 25th in the league for batting average this season (.231).
  • The Guardians rank 24th in the league for on-base percentage this season (.304).
  • The Dodgers rank 2nd in the league for slugging percentage this season (.459).
  • The Dodgers rank 2nd in the league for on-base percentage this season (.340).

Dodgers vs Guardians Prediction

The teams have traded wins in the past few years, each recording five in the previous ten H2H duels. The Dodgers were better in four of the last five H2Hs. Seven of Cleveland’s past ten games went Under, and I am going with another Under here because of strong starting pitchers. Gavin Williams allowed only five runs in his last four starts and recorded 6+ strikeouts in each. Yoshinobu Yamamoto experienced one weak start this month in a game against Arizona, but displayed a much better performance in the latest duel with the D-backs, keeping them off the scoreboard for 7.0 innings. I am backing both starters to have quality starts here and don’t allow more than four combined runs. I am going with Under.

Oliver Zivic's Pick: Under 8.5

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