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Los Angeles Angels vs Oakland Athletics Prediction 5/20/25 MLB Picks

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Oakland Athletics (22-26) vs Los Angeles Angels (21-25)

May 20, 2025 at 10:05 PM EDT

The Line: Betting Odds: Oakland Athletics -166 / Los Angeles Angels +140 — Over/Under: 10

(Get latest betting odds)

The Los Angeles Angels are visiting the Athletics on Tuesday, May 20th at the Sutter Health Park in the second game of this series, with the Angels having a 1-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Los Angeles Angels vs Athletics Prediction. We will examine:

The Athletics’ recent form and player performance

The Los Angeles Angels’ recent form and player performance

Recent betting trends and streaks involving the Athletics

Recent betting trends and streaks involving the Los Angeles Angels

Recent betting trends in games played between the Los Angeles Angels and the Athletics

A summary that ties it all together and produces a favorable betting outcome for the Los Angeles Angels vs Athletics game

Athletics Preview

The Athletics have a 22-26 record this season and are sitting in 4th place in the AL West. The Athletics have an 8-14 home record and are 24-20 in over/under. They are coming off a 3-4 home defeat by the Athletics, and are 2-10 in their last 12 games. Under is 3-0 in their last 4 games, and they are playing the Phillies and the Astros next.

The Athletics have a .251 batting average this season, a .313 OBP, and a .411 Slugging percentage. Athletics’ pitching staff has a 5.10 ERA and 1.48 WHIP. Jacob Wilson leads the Athletics with 62 hits and a team-high .343 batting average, while Tyler Soderstrom leads the team with 30 RBI, and Brent Booker adds a team-high 10 home runs.

Gunnar Hoglund (R) will take the mound for the Athletics, and he has a 1-1 record, 3.78 ERA, and 1.32 WHIP. In his only home start this season, he gave up two runs in 5.1 innings of work, in a 5-6 defeat by the Mariners. This will be his first career start against the Angels.   

Los Angeles Angels Preview

The Los Angeles Angels have a 21-25 record this season and are sitting in last place in the AL West. The Angels have a 12-15 road record and 26-20 in over/under. They are coming off a 4-3 road victory over the Athletics and have four consecutive wins. Over is 5-3 in their last 8 games, and they are playing the Marlins and the Yankees next.

The Angels have a .220 batting average this season, a .281 OBP, and a .400 Slugging percentage. LA’s pitching staff has a 5.04 ERA and 1.49 WHIP. Nolan Schanuel leads the Angels with 43 hits, and he is the team’s best hitter with a .277 batting average. Taylor Ward leads the team with 27 RBI and a team-high 13 home runs.

Kyle Hendricks (R) will take the mound for the Angels, and he has a 1-5 record, 5.18 ERA, and 1.22 WHIP. He has been weaker on the road with a 6.38 ERA across five road starts, and he has given up 3+ runs in five of his last six starts. Kyle Hendricks is 1-0 with an ERA of 1.98 and 9 strikeouts in 2 appearances against the Oakland Athletics in his career.

Why the Athletics will win

  • The Angels have lost nine of their last 10 road games against American League opponents.
  • The Athletics have won each of their last five night games against AL West opponents following a home loss.
  • The Angels have failed to cover the run line in nine of their last 10 road games against American League opponents.
  • The Athletics have covered the run line in each of their last five night games against AL West opponents following a home loss.
  • The Angels have trailed after 3 innings in seven of their last eight road games against American League opponents.
  • The Angels have trailed after 5 innings in four of their last five road games against American League opponents that held a losing record.
  • The Angels have lost the first inning in each of their last four road games against American League opponents that held a losing record.

Why the Los Angeles Angels will win

  • The Athletics have lost each of their last seven games after playing the previous day.
  • The Angels have won each of their last four games as underdogs.
  • The Athletics have failed to cover the run line each of their last eight home games against teams that held a losing record.
  • The Angels have covered the run line in each of their last four games.
  • The Angels have led after 5 innings in each of their last four games.
  • The Angels have led after 3 innings in each of their last four games.

Total Runs Facts

  • Each of the Athletics’ last five games as favorites have gone UNDER the total runs line.
  • Five of the Angels’ last six night games against AL West opponents have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Angels’ last six games.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in 14 of the Athletics’ last 16 home games against AL West opponents.

Matchup/League Facts

  • The Athletics rank 30th in the league for walks allowed this season (191).
  • The Athletics rank 29th in the league for hits allowed this season (441).
  • The Angels rank 30th in the league for hits this season (334).
  • The Angels rank 30th in the league for on-base percentage this season (.281).

Los Angeles Angels vs Athletics Prediction

The Athletics are 8-3 in their last 11 overall meetings against the Angels, and are 5-2 in their last 7 meetings in Oakland. Under is 3-1 in their last 4 meetings.

In this Los Angeles Angels vs Athletics Prediction, the Athletics are coming as -165 home favorites. The Athletics are rightfully favored, as they have the pitching advantage and the better bullpen, but they are up against a red-hot Angels squad that is coming off a series sweep against the Dodgers. Kyle Hendricks has been terrible this season, and the Angels won’t be winning forever. I like this as a bounce-back spot for the Athletics, as I certainly trust Hoglund more than Hendricks, and when the bullpens come in, the Angels are dead last in the MLB with a 6.92 bullpen ERA and 1.73 WHIP. Take the Athletics on the moneyline.

Nikos Lagouretos's Pick: Athletics ML

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