Chicago Cubs vs Miami Marlins Prediction 5/20/25 MLB Picks

The Chicago Cubs and Miami Marlins meet Tuesday in MLB action at loanDepot park. Here’s a Chicago Cubs vs Miami Marlins Prediction. This article will include a Chicago Cubs vs Miami Marlins Pick.

Chicago Cubs Betting Preview

The Chicago Cubs are 28-20 on the year and play the Reds, Rockies, and Reds next. The Chicago Cubs are batting .256 on the season, have a .332 OBP, and a .442 slugging percentage. The Chicago Cubs pitching staff has a 4.02 ERA and a 1.29 WHIP. Pete Crow-Armstrong leads the Chicago Cubs with 53 hits and 38 RBI, while Nico Hoerner and Kyle Tucker have combined for 99 hits and 53 RBI. 

Jameson Taillon gets the ball for the Chicago Cubs, and he is 2-3 with a 4.53 ERA and 42 strikeouts this season. Taillon is 3-1 with a 1.63 ERA and 22 strikeouts in his career against the Miami Marlins.

Miami Marlins Betting Preview

The Miami Marlins are 19-27 on the year and play the Angels, Padres, and Giants next. The Miami Marlins are batting .249 on the season, have a .313 OBP, and a .391 slugging percentage. The Miami Marlins’ pitching staff has a 5.37 ERA and a 1.47 WHIP. Kyle Stowers leads the Miami Marlins with 47 hits and 30 RBI, while Xavier Edwards and Eric Wagaman have combined for 82 hits and 23 RBI.

Ryan Weathers gets the ball for the Miami Marlins, and he is 1-0 with a 1.80 ERA and 5 strikeouts this season. Weathers is 2-2 with a 6.75 ERA and 15 strikeouts in his career against the Chicago Cubs.

Why the Miami Marlins will win

• The underdogs have won four of the Marlins’ last five games.
• The Cubs have lost four of their last six games as road favorites after playing the previous day.
• The Marlins have covered the run line in seven of their last eight night games against NL Central opponents that held a winning record.
• The Cubs have failed to cover the run line in five of their last six night games against NL East opponents that held a losing record.
• The Cubs have lost the first inning in three of their last four games as favorites.
• The Cubs have trailed after 5 innings in six of their last eight games at LoanDepot Park against National League opponents that held a losing record.

Why the Chicago Cubs will win

• The Cubs have won each of their last 11 games against National League opponents following a road loss.
• The Marlins have lost four of their last five games following a home win.
• The Cubs have covered the run line in seven of their last eight games against National League opponents following a road loss.
• The Marlins have failed to cover the run line in four of their last five night games against the Cubs at LoanDepot Park following a home win.
• The Cubs have led after 5 innings in three of their last four road games against NL East opponents that held a losing record.

Miami Marlins Player Prop Facts

• Jesus Sanchez has hit a home run in each of the Marlins’ last two games against the Cubs at LoanDepot Park.
• Jesus Sanchez has recorded at least one RBI in each of the Marlins’ last three games against NL opponents at LoanDepot Park.
• Otto Lopez has scored a run in seven of his last eight Tuesday appearances with the Marlins as underdogs.
• Jesus Sanchez has recorded at least one Single in each of the Marlins’ last six Tuesday night games against opponents that held a winning record.
• Otto Lopez has recorded at least one hit in 12 of his last 13 appearances at LoanDepot Park against opponents that held a winning record.

Chicago Cubs Player Prop Facts

• Justin Turner has recorded a Double in each of his last three appearances at LoanDepot Park against opponents that held a losing record.
• Nico Hoerner has scored at least one run in seven of the Cubs’ last eight games as favorites.
• Carson Kelly has recorded at least one Single in each of his six previous appearances with the Cubs as road favorites.
• Ian Happ has recorded an RBI in each of his last four road appearances against NL East opponents that held a losing record.
• Ian Happ has recorded at least one hit in each of his last 12 appearances with the Cubs as road favorites against NL opponents.
• Dansby Swanson has hit a home run in four of the Cubs’ last seven road games against NL opponents that held a losing record.
• Kyle Tucker ranks T6th in the league in Steals (13) this season.

Chicago Cubs vs Miami Marlins Prediction

The Cubs have obviously been the better team this season and should be favored, but this line is a bit thick. The Marlins continue to compete and have quietly won four of their last five games. Taillon has been hittable all season, and he’s allowed 16 hits and 10 earned runs in his last 16 innings. In 25.2 road innings, Taillon has a 5.96 ERA and a .276 allowed batting average. Weathers has just five innings under his belt this season, but those frames came against the Cubs, and he allowed two hits and one run while striking out five. We’re getting the home team at plus money against a pitcher who hasn’t been great. Give me the fish.